Synergistic effect of selected carboxylic acids and phenolic compounds detected by the FRAP method
Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances – antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was det...
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| Published in | Food Chemistry: X Vol. 23; p. 101573 |
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| Main Authors | , , |
| Format | Journal Article |
| Language | English |
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30.10.2024
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| Abstract | Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances – antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices.
•Synergistic effect on AC up to 8.9-fold for food compounds.•Increase in AC of real mixtures by up to 5.5 mM Trolox (ie +85% vs. hypothetical).•Compounds with low AC showed higher synergistic effects and vice versa.•Synergists improve the AC of real food. |
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| AbstractList | Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances - antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices.Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances - antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices. Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances - antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices. Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances – antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices. •Synergistic effect on AC up to 8.9-fold for food compounds.•Increase in AC of real mixtures by up to 5.5 mM Trolox (ie +85% vs. hypothetical).•Compounds with low AC showed higher synergistic effects and vice versa.•Synergists improve the AC of real food. Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances – antioxidants and potential synergists, whereby two substances were mixed in the same concentration ratio of 1:1. The antioxidant capacity (AC) of the mixtures was determined using the FRAP method. The AC measured was compared with a theoretical AC value (as only additive effect) to calculate the synergistic or antagonistic effect. Out of 78 possible combinations, a synergistic effect (SE) was detected in 72. For the 10 combinations, the SE was more than twice that of the pure substances. The largest synergistic effect was exhibited by vanillin and 4-hydroxybenzoic acid with increases even above 200% compared to the pure substances. Some of the phenolic substances that were subject to measurement can be used for the fortification of fruit juices. • Synergistic effect on AC up to 8.9-fold for food compounds. • Increase in AC of real mixtures by up to 5.5 mM Trolox (ie +85% vs. hypothetical). • Compounds with low AC showed higher synergistic effects and vice versa. • Synergists improve the AC of real food. |
| ArticleNumber | 101573 |
| Author | Soural, Ivo Balík, Josef Švestková, Petra |
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| Keywords | Antioxidants Polyphenols Synergistic effect Carboxylic acids Methoxyphenols FRAP (ferric reducing antioxidant power) |
| Language | English |
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| References | Híc, Soural, Balík, Kulichová, Vrchotová, Tříska (bb0045) 2017; 56 Wang, Meckling, Marcone, Kakuda, Tsao (bb0150) 2011; 59 Shi, Qua, Kakudab, Xue, Jiang, Koided, Shimb (bb0095) 2007; 20 Birben, Sahiner, Sackesen, Erzurum, Kalayci (bb0015) 2012; 5 Vicol (bb0145) 2022; 7 Dolas Ashadevi, Gotmare (bb0020) 2015; 6 Olszowy-Tomczyk (bb0080) 2020; 19 Ulanowska, Olas (bb0140) 2021; 22 Nikolaidis, Margaritelis (bb0070) 2023; 34 Skroza, Šimat, Vrdoljak, Jolić, Skelin, Čagalj, Frleta, Generalić Mekinić (bb0100) 2022; 11 Švestková, Soural, Balík, Bieniasz (bb0125) 2019 Motooka, Usami, Nakahashi, Koutari, Nakaya, Shimizu, Tsuji, Marumoto, Miyazawa (bb0060) 2015; 64 Munteanu, Apetrei (bb0065) 2021; 22 Hajimehdipoor, Shahrestani, Shekarchi (bb0040) 2014; 1 Soural, Švestková, Híc, Balík (bb0120) 2022; 51 Flieger, Flieger, Baj, Maciejewski (bb0030) 2021; 14 Ferreira, Lopez (bb0025) 2019; 9 Peyrat-Maillard, Cuvelier, Berset (bb0085) 2003; 80 Guo, Yang, Wei, Li, Xu, Jiang (bb0035) 2003; 23 Sonam, Guleria (bb0110) 2017; 2 Nowicka, Wojdyło, Teleszko (bb0075) 2017; 54 Katalinic (bb0050) 2015; 38 Benzie, Strain (bb0010) 1996; 239 Soural, Balík, Švestková, Híc, Šnurkovič (bb0115) 2020; 35156 Swada, Keeley, Ghane, Engeseth (bb0130) 2016; 199 Son, Moon, Lee (bb0105) 2001; 73 Thaipong, Boonprakob, Crosby, Cisneros-Zevallos, Byrne (bb0135) 2006; 19 Prior, Wu, Schaich (bb0090) 2005; 53 Martinović, Mihailovic, Maskovic, Solujić, Stojković, Muratspahić (bb0055) 2010; 48 Nowicka (10.1016/j.fochx.2024.101573_bb0075) 2017; 54 Soural (10.1016/j.fochx.2024.101573_bb0115) 2020; 35156 Prior (10.1016/j.fochx.2024.101573_bb0090) 2005; 53 Hajimehdipoor (10.1016/j.fochx.2024.101573_bb0040) 2014; 1 Ulanowska (10.1016/j.fochx.2024.101573_bb0140) 2021; 22 Dolas Ashadevi (10.1016/j.fochx.2024.101573_bb0020) 2015; 6 Flieger (10.1016/j.fochx.2024.101573_bb0030) 2021; 14 Švestková (10.1016/j.fochx.2024.101573_bb0125) 2019 Ferreira (10.1016/j.fochx.2024.101573_bb0025) 2019; 9 Katalinic (10.1016/j.fochx.2024.101573_bb0050) 2015; 38 Shi (10.1016/j.fochx.2024.101573_bb0095) 2007; 20 Benzie (10.1016/j.fochx.2024.101573_bb0010) 1996; 239 Olszowy-Tomczyk (10.1016/j.fochx.2024.101573_bb0080) 2020; 19 Son (10.1016/j.fochx.2024.101573_bb0105) 2001; 73 Peyrat-Maillard (10.1016/j.fochx.2024.101573_bb0085) 2003; 80 Swada (10.1016/j.fochx.2024.101573_bb0130) 2016; 199 Wang (10.1016/j.fochx.2024.101573_bb0150) 2011; 59 Skroza (10.1016/j.fochx.2024.101573_bb0100) 2022; 11 Híc (10.1016/j.fochx.2024.101573_bb0045) 2017; 56 Martinović (10.1016/j.fochx.2024.101573_bb0055) 2010; 48 Thaipong (10.1016/j.fochx.2024.101573_bb0135) 2006; 19 Nikolaidis (10.1016/j.fochx.2024.101573_bb0070) 2023; 34 Sonam (10.1016/j.fochx.2024.101573_bb0110) 2017; 2 Motooka (10.1016/j.fochx.2024.101573_bb0060) 2015; 64 Guo (10.1016/j.fochx.2024.101573_bb0035) 2003; 23 Soural (10.1016/j.fochx.2024.101573_bb0120) 2022; 51 Vicol (10.1016/j.fochx.2024.101573_bb0145) 2022; 7 Munteanu (10.1016/j.fochx.2024.101573_bb0065) 2021; 22 Birben (10.1016/j.fochx.2024.101573_bb0015) 2012; 5 |
| References_xml | – start-page: 659 year: 2019 end-page: 664 ident: bb0125 article-title: The effect of substituents on aromatic ring on antioxidant capacity of phenolic substances publication-title: MendelNet 2019: Proceedings of 26th international PhD students conference. 1. Vyd. Brno: Mendel university in Brno, s. – volume: 19 start-page: 669 year: 2006 end-page: 675 ident: bb0135 article-title: Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts publication-title: Journal of Food Composition and Analysis – volume: 2 start-page: 1086 year: 2017 ident: bb0110 article-title: Synergistic antioxidant activity of natural products publication-title: Annals Pharmacology Pharmaceutics – volume: 35156 year: 2020 ident: bb0115 article-title: Fruit drink with the addition of antioxidants publication-title: Industrial Property Office, Czech Republic, Utility Models No – volume: 5 start-page: 9 year: 2012 end-page: 19 ident: bb0015 article-title: Oxidative stress and antioxidant defense publication-title: World Allergy Organization Journal – volume: 14 start-page: 4135 year: 2021 ident: bb0030 article-title: Antioxidants: Classification, natural sources, activity/capacity measurements, and usefulness for the synthesis of nanoparticles publication-title: Materials (Basel) – volume: 54 start-page: 114 year: 2017 end-page: 129 ident: bb0075 article-title: Effect of mixing different kinds of fruit juice with sour cherry puree on nutritional properties publication-title: Journal of Food Science and Technology – volume: 1 start-page: 35 year: 2014 end-page: 40 ident: bb0040 article-title: Investigating the synergistic antioxidant effects of some flavonoid and phenolic compounds publication-title: Research Journal of Pharmacognosy – volume: 6 start-page: 25 year: 2015 end-page: 30 ident: bb0020 article-title: The health benefits and risks of antioxidants publication-title: Pharmacophore – volume: 80 start-page: 1007 year: 2003 end-page: 1012 ident: bb0085 article-title: Antioxidant activity of phenolic compounds in 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced oxidation: Synergistic and antagonistic effects publication-title: Journal of the American Oil Chemists’ Society – volume: 53 start-page: 4290 year: 2005 end-page: 4302 ident: bb0090 article-title: Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements publication-title: Journal of Agricultural and Food Chemistry – volume: 22 start-page: 3380 year: 2021 ident: bb0065 article-title: Analytical methods used in determining antioxidant activity: A review publication-title: International Journal of Molecular Sciences – volume: 48 start-page: 3125 year: 2010 end-page: 3130 ident: bb0055 article-title: Antioxidant activity of selected plant species: Potential new sources of natural antioxidants publication-title: Food and Chemical Toxicology. an International Journal published for the British Industrial Biological Research Association – volume: 34 start-page: 503 year: 2023 end-page: 504 ident: bb0070 article-title: Free radicals and antioxidants: Appealing to magic publication-title: Trends in Endocrinology Metabolism – volume: 11 start-page: 1784 year: 2022 ident: bb0100 article-title: Investigation of antioxidant synergisms and antagonisms among phenolic acids in the model matrices using FRAP and ORAC methods publication-title: Antioxidants – volume: 23 start-page: 1719 year: 2003 end-page: 1726 ident: bb0035 article-title: Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay publication-title: Nutrition Research – volume: 59 start-page: 960 year: 2011 end-page: 968 ident: bb0150 article-title: Synergistic, additive, and antagonistic effects of food mixtures on total antioxidant capacities publication-title: Journal of Agricultural and Food Chemistry – volume: 22 start-page: 3671 year: 2021 ident: bb0140 article-title: Biological properties and prospects for the application of eugenol—a review publication-title: International Journal of Molecular Sciences – volume: 9 start-page: 818 year: 2019 ident: bb0025 article-title: The actual and potential aroma of winemaking grapes publication-title: Biomolecules – volume: 20 start-page: 60 year: 2007 end-page: 608 ident: bb0095 article-title: Investigation of the antioxidant and synergistic activity of lycopene and other natural antioxidants using LAME and AMVN model systems publication-title: Journal of Food Composition and Analysis – volume: 64 start-page: 577 year: 2015 end-page: 584 ident: bb0060 article-title: Characteristic odor components of essential oils from Eurya japonica publication-title: Journal of Oleo Science – volume: 19 start-page: 63 year: 2020 end-page: 103 ident: bb0080 article-title: Synergistic, antagonistic and additive antioxidant effects in the binary mixtures publication-title: Phytochemistry Reviews – volume: 239 start-page: 70 year: 1996 end-page: 76 ident: bb0010 article-title: The ferric reducing ability of plasma (FRAP) as a measure of “anti-oxidant power”: The FRAP assay publication-title: Analytical Biochemistry – volume: 7 start-page: 56 year: 2022 ident: bb0145 article-title: Study of synergic and anti-synergic interactions of some grape antioxidants with organic acids publication-title: Ecological and environmental chemistry – volume: 56 start-page: 129 year: 2017 end-page: 137 ident: bb0045 article-title: Antioxidant capacities of extracts in relation to toasting oak and acacia wood publication-title: Journal of Food and Nutrition Research – volume: 73 start-page: 23 year: 2001 end-page: 30 ident: bb0105 article-title: Inhibitory effects of various antibrowning agents on apple slices publication-title: Food Chemistry – volume: 51 start-page: 84 year: 2022 end-page: 92 ident: bb0120 article-title: Different values obtained by the FRAP method for the determination of slowly and rapidly reacting phenols publication-title: Acta Alimentaria – volume: 199 start-page: 87 year: 2016 end-page: 95 ident: bb0130 article-title: Synergistic potential of papaya and strawberry nectar blends focused on specific nutrients and antioxidants using alternative thermal and non-thermal processing techniques publication-title: Food Chemistry – volume: 38 start-page: 13 year: 2015 end-page: 18 ident: bb0050 article-title: Investigation of the potential synergistic effect of resveratrol with other phenolic compounds: A case of binary phenolic mixtures publication-title: Jornal of Food Composition Analysis – volume: 19 start-page: 63 year: 2020 ident: 10.1016/j.fochx.2024.101573_bb0080 article-title: Synergistic, antagonistic and additive antioxidant effects in the binary mixtures publication-title: Phytochemistry Reviews doi: 10.1007/s11101-019-09658-4 – volume: 73 start-page: 23 year: 2001 ident: 10.1016/j.fochx.2024.101573_bb0105 article-title: Inhibitory effects of various antibrowning agents on apple slices publication-title: Food Chemistry doi: 10.1016/S0308-8146(00)00274-0 – volume: 20 start-page: 60 year: 2007 ident: 10.1016/j.fochx.2024.101573_bb0095 article-title: Investigation of the antioxidant and synergistic activity of lycopene and other natural antioxidants using LAME and AMVN model systems publication-title: Journal of Food Composition and Analysis doi: 10.1016/j.jfca.2007.03.004 – volume: 7 start-page: 56 issue: 1 year: 2022 ident: 10.1016/j.fochx.2024.101573_bb0145 article-title: Study of synergic and anti-synergic interactions of some grape antioxidants with organic acids publication-title: Ecological and environmental chemistry – volume: 6 start-page: 25 issue: 1 year: 2015 ident: 10.1016/j.fochx.2024.101573_bb0020 article-title: The health benefits and risks of antioxidants publication-title: Pharmacophore – volume: 80 start-page: 1007 year: 2003 ident: 10.1016/j.fochx.2024.101573_bb0085 article-title: Antioxidant activity of phenolic compounds in 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH)-induced oxidation: Synergistic and antagonistic effects publication-title: Journal of the American Oil Chemists’ Society doi: 10.1007/s11746-003-0812-z – volume: 48 start-page: 3125 year: 2010 ident: 10.1016/j.fochx.2024.101573_bb0055 article-title: Antioxidant activity of selected plant species: Potential new sources of natural antioxidants publication-title: Food and Chemical Toxicology. an International Journal published for the British Industrial Biological Research Association doi: 10.1016/j.fct.2010.08.007 – volume: 54 start-page: 114 year: 2017 ident: 10.1016/j.fochx.2024.101573_bb0075 article-title: Effect of mixing different kinds of fruit juice with sour cherry puree on nutritional properties publication-title: Journal of Food Science and Technology doi: 10.1007/s13197-016-2442-2 – volume: 22 start-page: 3380 issue: 7 year: 2021 ident: 10.1016/j.fochx.2024.101573_bb0065 article-title: Analytical methods used in determining antioxidant activity: A review publication-title: International Journal of Molecular Sciences doi: 10.3390/ijms22073380 – volume: 199 start-page: 87 year: 2016 ident: 10.1016/j.fochx.2024.101573_bb0130 article-title: Synergistic potential of papaya and strawberry nectar blends focused on specific nutrients and antioxidants using alternative thermal and non-thermal processing techniques publication-title: Food Chemistry doi: 10.1016/j.foodchem.2015.11.087 – volume: 35156 year: 2020 ident: 10.1016/j.fochx.2024.101573_bb0115 article-title: Fruit drink with the addition of antioxidants publication-title: Industrial Property Office, Czech Republic, Utility Models No – volume: 1 start-page: 35 issue: 3 year: 2014 ident: 10.1016/j.fochx.2024.101573_bb0040 article-title: Investigating the synergistic antioxidant effects of some flavonoid and phenolic compounds publication-title: Research Journal of Pharmacognosy – volume: 11 start-page: 1784 issue: 9 year: 2022 ident: 10.1016/j.fochx.2024.101573_bb0100 article-title: Investigation of antioxidant synergisms and antagonisms among phenolic acids in the model matrices using FRAP and ORAC methods publication-title: Antioxidants doi: 10.3390/antiox11091784 – volume: 19 start-page: 669 issue: 6–7 year: 2006 ident: 10.1016/j.fochx.2024.101573_bb0135 article-title: Comparison of ABTS, DPPH, FRAP, and ORAC assays for estimating antioxidant activity from guava fruit extracts publication-title: Journal of Food Composition and Analysis doi: 10.1016/j.jfca.2006.01.003 – volume: 64 start-page: 577 issue: 5 year: 2015 ident: 10.1016/j.fochx.2024.101573_bb0060 article-title: Characteristic odor components of essential oils from Eurya japonica publication-title: Journal of Oleo Science doi: 10.5650/jos.ess14225 – volume: 23 start-page: 1719 issue: 12 year: 2003 ident: 10.1016/j.fochx.2024.101573_bb0035 article-title: Antioxidant activities of peel, pulp and seed fractions of common fruits as determined by FRAP assay publication-title: Nutrition Research doi: 10.1016/j.nutres.2003.08.005 – volume: 22 start-page: 3671 year: 2021 ident: 10.1016/j.fochx.2024.101573_bb0140 article-title: Biological properties and prospects for the application of eugenol—a review publication-title: International Journal of Molecular Sciences doi: 10.3390/ijms22073671 – volume: 239 start-page: 70 issue: 1 year: 1996 ident: 10.1016/j.fochx.2024.101573_bb0010 article-title: The ferric reducing ability of plasma (FRAP) as a measure of “anti-oxidant power”: The FRAP assay publication-title: Analytical Biochemistry doi: 10.1006/abio.1996.0292 – volume: 51 start-page: 84 issue: 1 year: 2022 ident: 10.1016/j.fochx.2024.101573_bb0120 article-title: Different values obtained by the FRAP method for the determination of slowly and rapidly reacting phenols publication-title: Acta Alimentaria doi: 10.1556/066.2021.00168 – volume: 2 start-page: 1086 issue: 8 year: 2017 ident: 10.1016/j.fochx.2024.101573_bb0110 article-title: Synergistic antioxidant activity of natural products publication-title: Annals Pharmacology Pharmaceutics – volume: 56 start-page: 129 issue: 2 year: 2017 ident: 10.1016/j.fochx.2024.101573_bb0045 article-title: Antioxidant capacities of extracts in relation to toasting oak and acacia wood publication-title: Journal of Food and Nutrition Research – volume: 9 start-page: 818 issue: 12 year: 2019 ident: 10.1016/j.fochx.2024.101573_bb0025 article-title: The actual and potential aroma of winemaking grapes publication-title: Biomolecules doi: 10.3390/biom9120818 – volume: 38 start-page: 13 year: 2015 ident: 10.1016/j.fochx.2024.101573_bb0050 article-title: Investigation of the potential synergistic effect of resveratrol with other phenolic compounds: A case of binary phenolic mixtures publication-title: Jornal of Food Composition Analysis doi: 10.1016/j.jfca.2014.06.013 – volume: 59 start-page: 960 issue: 3 year: 2011 ident: 10.1016/j.fochx.2024.101573_bb0150 article-title: Synergistic, additive, and antagonistic effects of food mixtures on total antioxidant capacities publication-title: Journal of Agricultural and Food Chemistry doi: 10.1021/jf1040977 – start-page: 659 year: 2019 ident: 10.1016/j.fochx.2024.101573_bb0125 article-title: The effect of substituents on aromatic ring on antioxidant capacity of phenolic substances – volume: 14 start-page: 4135 issue: 15 year: 2021 ident: 10.1016/j.fochx.2024.101573_bb0030 article-title: Antioxidants: Classification, natural sources, activity/capacity measurements, and usefulness for the synthesis of nanoparticles publication-title: Materials (Basel) doi: 10.3390/ma14154135 – volume: 5 start-page: 9 issue: 1 year: 2012 ident: 10.1016/j.fochx.2024.101573_bb0015 article-title: Oxidative stress and antioxidant defense publication-title: World Allergy Organization Journal doi: 10.1097/WOX.0b013e3182439613 – volume: 34 start-page: 503 issue: 9 year: 2023 ident: 10.1016/j.fochx.2024.101573_bb0070 article-title: Free radicals and antioxidants: Appealing to magic publication-title: Trends in Endocrinology Metabolism doi: 10.1016/j.tem.2023.06.001 – volume: 53 start-page: 4290 issue: 10 year: 2005 ident: 10.1016/j.fochx.2024.101573_bb0090 article-title: Standardized methods for the determination of antioxidant capacity and phenolics in foods and dietary supplements publication-title: Journal of Agricultural and Food Chemistry doi: 10.1021/jf0502698 |
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| Snippet | Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances – antioxidants and... Antioxidants in nutrition are a widely discussed topic. In this study, a synergistic effect was observed for 13 selected substances - antioxidants and... |
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| SubjectTerms | Antioxidants Carboxylic acids FRAP (ferric reducing antioxidant power) Methoxyphenols Polyphenols Synergistic effect |
| Title | Synergistic effect of selected carboxylic acids and phenolic compounds detected by the FRAP method |
| URI | https://dx.doi.org/10.1016/j.fochx.2024.101573 https://www.ncbi.nlm.nih.gov/pubmed/39050678 https://www.proquest.com/docview/3084770642 https://pubmed.ncbi.nlm.nih.gov/PMC11268200 https://doaj.org/article/48906251b76047119fb87457211bd804 |
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