An experimental model of contusion injury in humans

• Published in: PloS one Vol. 17; no. 11; p. e0277765
• Main Authors: Barnes, Matthew J, Lomiwes, Dominic, Parry, David A D, Mackintosh, Stephen
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.11.2022; Public Library of Science (PLoS)
• Subjects: Animals; Biology and Life Sciences; Contusions; Creatine; Creatine Kinase; Edema; Electric contacts; Humans; Impact loads; Injuries; Interleukin; Interleukin 6; Kinases; Load; Magnetic resonance; Magnetic resonance imaging; Male; Medicine and Health Sciences; Models, Theoretical; Muscle contraction; Muscle, Skeletal - physiology; Muscles; Pain; Physiological responses; Physiology; Polyvinyl chloride; Pressure; Quadriceps Muscle; Recovery (Medical); Research and Analysis Methods; Skeletal muscle; Sports related injuries; Trauma

Contusion injuries are common in sport, but our knowledge of the responses to injury primarily come from animal studies and research using eccentric exercise. Therefore, the aim of this study was to develop a model of contusion injury in human participants and, additionally, investigate and compare...