Fully-coupled fluid-structure interaction simulation of the aortic and mitral valves in a realistic 3D left ventricle model

• Published in: PloS one Vol. 12; no. 9; p. e0184729
• Main Authors: Mao, Wenbin, Caballero, Andrés, McKay, Raymond, Primiano, Charles, Sun, Wei
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 08.09.2017; Public Library of Science (PLoS)
• Subjects: Angles (geometry); Aorta; Aortic Valve - physiology; Biology and Life Sciences; Biomechanics; Biomedical engineering; Cardiology; Clinical decision making; Computational fluid dynamics; Computational physics; Computer simulation; Decision making; Echocardiography; Engineering; Finite Element Analysis; Finite element method; Fluid dynamics; Fluid flow; Fluid-structure interaction; Heart; Heart diseases; Heart valves; Hemodynamics; Hemodynamics - physiology; Humans; Hydrodynamics; Iron; Kinematics; Laboratories; Mathematical models; Medical imaging; Medicine and Health Sciences; Methods; Mitral Valve - physiology; Models, Biological; Physical Sciences; Physiology; Simulation; Smooth particle hydrodynamics; Studies; Surgery; Thoracic surgery; Three dimensional models; Ventricle; Atlanta Georgia; United States > US; Connecticut

In this study, we present a fully-coupled fluid-structure interaction (FSI) framework that combines smoothed particle hydrodynamics (SPH) and nonlinear finite element (FE) method to investigate the coupled aortic and mitral valves structural response and the bulk intraventricular hemodynamics in a r...