Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting

AbstractEmerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening...

Full description

Saved in:
Bibliographic Details
Published inJournal of Prevention of Alzheimer's Disease, The Vol. 7; no. 3; pp. 171 - 178
Main Authors Sabbagh, Marwan N, Boada, M, Borson, S, Doraiswamy, P.M, Dubois, B, Ingram, J, Iwata, A, Porsteinsson, A.P, Possin, K.L, Rabinovici, G.D, Vellas, B, Chao, S, Vergallo, A, Hampel, H
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 01.06.2020
SERDI éd
Subjects
Online AccessGet full text

Cover

Loading…
Abstract AbstractEmerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user' behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, selfassessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.
AbstractList Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user’s behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, self-assessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.
Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user’ behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, selfassessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.
Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user's behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, self-assessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user's behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, self-assessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.
AbstractEmerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the ubiquity of consumer electronics, such as smartphones and tablets, can be harnessed to support large-scale self-assessed cognitive screening with benefit to healthcare systems and consumers. A wide variety of apps, wearables, and new digital technologies are either available or in development for the detection of mild cognitive impairment (MCI), a risk factor for dementia. Two categories of novel methodologies may be considered: passive technologies (which monitor a user' behavior without active user input) and interactive assessments (which require active user input). Such examinations can be self-administered, supervised by a caregiver, or conducted by an informant at home or outside of a clinical setting. These direct-to-consumer tools have the potential to sidestep barriers associated with cognitive evaluation in primary care, thus improving access to cognitive assessments. Although direct-to-consumer cognitive assessment is associated with its own barriers, including test validation, user experience, and technological concerns, it is conceivable that these issues can be addressed so that a large-scale, selfassessed cognitive evaluation that would represent an initial cognitive screen may be feasible in the future.
Author Vellas, B
Ingram, J
Doraiswamy, P.M
Possin, K.L
Dubois, B
Hampel, H
Borson, S
Chao, S
Sabbagh, Marwan N
Rabinovici, G.D
Vergallo, A
Boada, M
Iwata, A
Porsteinsson, A.P
Author_xml – sequence: 1
  fullname: Sabbagh, Marwan N
– sequence: 2
  fullname: Boada, M
– sequence: 3
  fullname: Borson, S
– sequence: 4
  fullname: Doraiswamy, P.M
– sequence: 5
  fullname: Dubois, B
– sequence: 6
  fullname: Ingram, J
– sequence: 7
  fullname: Iwata, A
– sequence: 8
  fullname: Porsteinsson, A.P
– sequence: 9
  fullname: Possin, K.L
– sequence: 10
  fullname: Rabinovici, G.D
– sequence: 11
  fullname: Vellas, B
– sequence: 12
  fullname: Chao, S
– sequence: 13
  fullname: Vergallo, A
– sequence: 14
  fullname: Hampel, H
BackLink https://www.ncbi.nlm.nih.gov/pubmed/32463070$$D View this record in MEDLINE/PubMed
https://hal.science/hal-04549431$$DView record in HAL
BookMark eNp1ks9v0zAcxSM0xMbYkSvycTukfP0jTnpBqrpBK3XiMDhbrvNN8UjsYruV-t_jkDEkpB0sW9bnPcvvfd8WZ847LIr3FGZUsIZ_fNzrdsaAwYyxV8UFE0yWwKQ8y2dWi7JqoD4vrmK0W6hAAuU1e1OccyYkhxouitWdDv2J3GJCk6x3xHfk3vYtWfqds8kekayHvbZhQJfI9f1yfUOsI9qRRSpXfkDygClZt3tXvO50H_Hqab8svn---7ZclZuvX9bLxaY0FZOp1LA1VFYoDaOUdkK2lM01b5uO6znUdQdVw2vcMi6Az1tKjexMzatGdF3bIPDL4mby_aF7tQ920OGkvLZqtdio8Q5EJeaC0yPN7PXE7oP_dcCY1GCjwb7XDv0hKiagzs_ROcvohyf0sB2wfXb-m1QGygkwwccYsHtGKKg_ZaixDDWWodhoyP_jjU16jDgFbfsXVbNJFbO722FQj_4QXA70RcGnSYA586PNAtNbZ43uf-IJ4z-1ikyBehinYhyK_HUQefHf1zKtZw
CitedBy_id crossref_primary_10_1001_jamanetworkopen_2023_33786
crossref_primary_10_1159_000541627
crossref_primary_10_14283_jpad_2024_68
crossref_primary_10_2196_56433
crossref_primary_10_14283_jpad_2024_99
crossref_primary_10_2196_54299
crossref_primary_10_3389_fnhum_2024_1304221
crossref_primary_10_3389_fpsyg_2023_1197567
crossref_primary_10_1109_ACCESS_2024_3442431
crossref_primary_10_1109_MIM_2021_9513645
crossref_primary_10_18632_aging_204533
crossref_primary_10_1002_alz_14377
crossref_primary_10_3233_JAD_200936
crossref_primary_10_3389_fdgth_2024_1265846
crossref_primary_10_3389_fnagi_2023_1134096
crossref_primary_10_1186_s12905_024_03251_4
crossref_primary_10_3389_frdem_2023_1135451
crossref_primary_10_1080_13803395_2025_2464633
crossref_primary_10_3310_XLUJ6074
crossref_primary_10_2196_42416
crossref_primary_10_2196_45658
Cites_doi 10.1016/j.jalz.2018.02.018
10.1017/S1041610205001687
10.3233/JAD-150265
10.3233/JAD-2010-1354
10.3233/JAD-150520
10.1016/j.eurpsy.2011.04.006
10.1001/jama.288.12.1475
10.1038/s41582-018-0079-7
10.1016/j.jalz.2019.01.007
10.1177/1533317512470484
10.1159/000445831
10.1016/j.jalz.2013.01.013
10.1111/joim.12190
10.2196/12785
10.1097/YCO.0000000000000397
10.1186/s13195-017-0269-3
10.1016/j.jalz.2011.05.2410
10.1016/j.dadm.2015.10.005
10.1016/j.trci.2018.09.008
ContentType Journal Article
Copyright THE AUTHORS. Published by Elsevier Masson SAS on behalf of SERDI Publisher.
The Author(s) 2020
Attribution
Copyright_xml – notice: THE AUTHORS. Published by Elsevier Masson SAS on behalf of SERDI Publisher.
– notice: The Author(s) 2020
– notice: Attribution
DBID C6C
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
7X8
1XC
VOOES
DOI 10.14283/jpad.2020.22
DatabaseName SpringerOpen Free (Free internet resource, activated by CARLI)
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
MEDLINE - Academic
Hyper Article en Ligne (HAL)
Hyper Article en Ligne (HAL) (Open Access)
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
MEDLINE - Academic
DatabaseTitleList

MEDLINE - Academic

MEDLINE
Database_xml – sequence: 1
  dbid: C6C
  name: SpringerOpen Free (Free internet resource, activated by CARLI)
  url: http://www.springeropen.com/
  sourceTypes: Publisher
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2426-0266
EndPage 178
ExternalDocumentID oai_HAL_hal_04549431v1
32463070
10_14283_jpad_2020_22
1_s2_0_S2274580724004400
Genre Research Support, Non-U.S. Gov't
Journal Article
Review
GrantInformation_xml – fundername: NIA NIH HHS
  grantid: U01 AG016976
– fundername: NIA NIH HHS
  grantid: U24 AG072122
GroupedDBID ABFSG
ACSTC
ACVFH
ADCNI
AEUPX
AEZWR
AFHIU
AFPUW
AHWEU
AIGII
AIXLP
AKBMS
AKYEP
-EM
406
AACDK
AAHNG
AAJBT
AALRI
AASML
AATNV
AAUYE
AAXUO
ABAKF
ABDZT
ABECU
ABFTV
ABKCH
ABMQK
ABTEG
ABTKH
ACAOD
ACHSB
ACOKC
ACPIV
ACZOJ
ADKNI
ADURQ
ADYFF
AEFQL
AEMSY
AESKC
AFQWF
AGDGC
AGJBK
AGMZJ
AGQEE
AGRTI
AIAKS
AIGIU
AILAN
AITGF
AJZVZ
ALMA_UNASSIGNED_HOLDINGS
AMKLP
AMXSW
AMYLF
AXYYD
BGNMA
C6C
DPUIP
EBLON
EBS
EJD
FDB
FIGPU
FINBP
FNLPD
FSGXE
GGCAI
IKXTQ
IWAJR
J-C
JZLTJ
KOV
LLZTM
M41
M4Y
NPVJJ
NQJWS
NU0
O9J
PT4
ROL
RSV
SJN
SJYHP
SNE
SNPRN
SOHCF
SOJ
SRMVM
SSLCW
STPWE
UOJIU
UTJUX
VEKWB
VFIZW
ZMTXR
AAYXX
CITATION
.1-
.FO
0R~
AAFWJ
AAYWO
AFOHR
AFPKN
AFRHN
AHPBZ
AJUYK
APXCP
ATHPR
AYFIA
CGR
CUY
CVF
ECM
EIF
GROUPED_DOAJ
NPM
RPM
Z5R
7X8
1XC
VOOES
ID FETCH-LOGICAL-c526t-a0bc165e6c2111f46d129a3d8f3a9077f05837eb234039d11c6fc73584ffd8e03
IEDL.DBID C6C
ISSN 2274-5807
2426-0266
IngestDate Wed Jun 11 06:20:48 EDT 2025
Fri Jul 11 11:33:20 EDT 2025
Mon Jul 21 05:40:28 EDT 2025
Tue Jul 01 02:20:33 EDT 2025
Thu Apr 24 22:56:15 EDT 2025
Fri Feb 21 02:45:37 EST 2025
Fri Aug 22 09:50:56 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Keywords mild cognitive impairment
cognitive screening
digital consumer
Alzheimer's disease
Alzheimer’s disease
Language English
License Attribution: http://creativecommons.org/licenses/by
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c526t-a0bc165e6c2111f46d129a3d8f3a9077f05837eb234039d11c6fc73584ffd8e03
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ORCID 0000-0003-0894-8982
0000-0002-7678-5065
OpenAccessLink https://doi.org/10.14283/jpad.2020.22
PMID 32463070
PQID 2407583192
PQPubID 23479
PageCount 8
ParticipantIDs hal_primary_oai_HAL_hal_04549431v1
proquest_miscellaneous_2407583192
pubmed_primary_32463070
crossref_primary_10_14283_jpad_2020_22
crossref_citationtrail_10_14283_jpad_2020_22
springer_journals_10_14283_jpad_2020_22
elsevier_clinicalkeyesjournals_1_s2_0_S2274580724004400
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 20200600
PublicationDateYYYYMMDD 2020-06-01
PublicationDate_xml – month: 6
  year: 2020
  text: 20200600
PublicationDecade 2020
PublicationPlace Cham
PublicationPlace_xml – name: Cham
– name: Switzerland
PublicationTitle Journal of Prevention of Alzheimer's Disease, The
PublicationTitleAbbrev J Prev Alzheimers Dis
PublicationTitleAlternate J Prev Alzheimers Dis
PublicationYear 2020
Publisher Springer International Publishing
SERDI éd
Publisher_xml – name: Springer International Publishing
– name: SERDI éd
References Petersen, Caracciolo, Brayne, Gauthier, Jelic, Fratiglioni (CR1) 2014; 275
Nosheny, Camacho, Insel (CR15) 2018; 4
de Leonni Stanonik, Licata, Walton, Lounsbury, Hutson, Dougherty (CR9) 2005; 17
Sano, Zhu, Kaye (CR12) 2019; 15
CR39
CR14
Henriksen, O’Bryant, Hampel (CR33) 2014; 10
CR36
Jack, Bennett, Blennow (CR2) 2018; 14
Zeitzer, David, Friedman (CR22) 2013; 21
CR35
CR34
CR10
Naismith, Mowszowski (CR19) 2018; 31
Fraser, Meltzer, Rudzicz (CR31) 2016; 49
Zola, Manzanares, Clopton, Lah, Levey (CR18) 2013; 28
Bahureksa, Najafi, Saleh (CR20) 2017; 63
Tarnanas, Tsolaki, Wiederhold, Wiederhold, Tsolaki (CR29) 2015; 1
CR30
Lyketsos, Carrillo, Ryan (CR4) 2011; 7
Hampel, O’Bryant, Molinuevo (CR32) 2018; 14
David, Mulin, Friedman (CR7) 2012; 20
CR3
Dodge, Zhu, Mattek, Austin, Kornfeld, Kaye (CR23) 2015
CR8
Dougherty, Cannon, Nicholas (CR38) 2010; 20
CR28
Piau, Wild, Mattek, Kaye (CR11) 2019; 21
CR26
Mackin, Insel, Truran (CR16) 2018; 10
CR25
Kuhlmei, Walther, Becker, Muller, Nikolaus (CR6) 2013; 28
Scharre, Chang, Nagaraja, Vrettos, Bornstein (CR37) 2017; 9
Jekel, Damian, Storf, Hausner, Frolich (CR24) 2016; 52
Li, Yu, Meng, Lu, Kwok, Cheng (CR27) 2018
Lyketsos, Lopez, Jones, Fitzpatrick, Breitner, DeKosky (CR5) 2002; 288
Weiner, Nosheny, Camacho (CR13) 2018; 14
Fernandez, Manes, Politi (CR17) 2016; 50
Mulin, Zeitzer, Friedman (CR21) 2011; 25
Bahureksa (10.14283/jpad.2020.22_bib20) 2017; 63
Mulin (10.14283/jpad.2020.22_bib21) 2011; 25
Zeitzer (10.14283/jpad.2020.22_bib22) 2013; 21
Li (10.14283/jpad.2020.22_bib27) 2018
de Leonni Stanonik (10.14283/jpad.2020.22_bib9) 2005; 17
Hampel (10.14283/jpad.2020.22_bib32) 2018; 14
Naismith (10.14283/jpad.2020.22_bib19) 2018; 31
Tarnanas (10.14283/jpad.2020.22_bib29) 2015; 1
Fernandez (10.14283/jpad.2020.22_bib17) 2016; 50
Dodge (10.14283/jpad.2020.22_bib23) 2015
Dougherty (10.14283/jpad.2020.22_bib38) 2010; 20
10.14283/jpad.2020.22_bib28
Jekel (10.14283/jpad.2020.22_bib24) 2016; 52
Nosheny (10.14283/jpad.2020.22_bib15) 2018; 4
Mackin (10.14283/jpad.2020.22_bib16) 2018; 10
David (10.14283/jpad.2020.22_bib7) 2012; 20
Jack (10.14283/jpad.2020.22_bib2) 2018; 14
Sano (10.14283/jpad.2020.22_bib12) 2019; 15
Zola (10.14283/jpad.2020.22_bib18) 2013; 28
Fraser (10.14283/jpad.2020.22_bib31) 2016; 49
Petersen (10.14283/jpad.2020.22_bib1) 2014; 275
Lyketsos (10.14283/jpad.2020.22_bib5) 2002; 288
Piau (10.14283/jpad.2020.22_bib11) 2019; 21
Winterlight Labs (10.14283/jpad.2020.22_bib30)
Kuhlmei (10.14283/jpad.2020.22_bib6) 2013; 28
Lyketsos (10.14283/jpad.2020.22_bib4) 2011; 7
Scharre (10.14283/jpad.2020.22_bib37) 2017; 9
Weiner (10.14283/jpad.2020.22_bib13) 2018; 14
Henriksen (10.14283/jpad.2020.22_bib33) 2014; 10
References_xml – volume: 1
  start-page: 521
  year: 2015
  end-page: 532
  ident: CR29
  article-title: Five year biomarker progression variability for Alzheimer’s disease dementia prediction: Can a complex instrumental activities of daily living marker fill in the gaps?
  publication-title: Alzheimers Dement Amst Neth
– volume: 10
  start-page: 573.582
  year: 2018
  ident: CR16
  article-title: Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry
  publication-title: Alzheimers Dement Amst Neth
– volume: 14
  start-page: 535
  year: 2018
  end-page: 562
  ident: CR2
  article-title: NIA-AA Research Framework: Toward a biological definition of Alzheimer’s disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2018.02.018
– start-page: 10
  year: 2015
  ident: CR23
  article-title: Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials
  publication-title: PLoS ONE
– volume: 52
  start-page: 509.517
  year: 2016
  ident: CR24
  article-title: Development of a Proxy-Free Objective Assessment Tool of Instrumental Activities of Daily Living in Mild Cognitive Impairment Using Smart Home Technologies
  publication-title: J Alzheimers Dis JAD
– volume: 17
  start-page: 669
  year: 2005
  end-page: 678
  ident: CR9
  article-title: The Self Test: a screening tool for dementia requiring minimal supervision
  publication-title: Int Psychogeriatr
  doi: 10.1017/S1041610205001687
– volume: 50
  start-page: 827
  year: 2016
  end-page: 838
  ident: CR17
  article-title: Patients with Mild Alzheimer’s Disease Fail When Using Their Working Memory: Evidence from the Eye Tracking Technique
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-150265
– volume: 20
  start-page: 185
  year: 2010
  end-page: 195
  ident: CR38
  article-title: The computerized self test (CST): an interactive, internet accessible cognitive screening test for dementia
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-2010-1354
– ident: CR14
– volume: 49
  start-page: 407
  year: 2016
  end-page: 422
  ident: CR31
  article-title: Linguistic Features Identify Alzheimer’s Disease in Narrative Speech
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-150520
– ident: CR39
– ident: CR30
– volume: 25
  start-page: 85.91
  year: 2011
  ident: CR21
  article-title: Relationship between apathy and sleep disturbance in mild and moderate Alzheimer’s disease: an actigraphic study
  publication-title: J Alzheimers Dis JAD
– ident: CR10
– volume: 20
  start-page: 806.814
  year: 2012
  ident: CR7
  article-title: Decreased daytime motor activity associated with apathy in Alzheimer disease: an actigraphic study
  publication-title: Am J Geriatr Psychiatry Off J Am Assoc Geriatr Psychiatry
– ident: CR35
– volume: 28
  start-page: 94
  year: 2013
  end-page: 97
  ident: CR6
  article-title: Actigraphic daytime activity is reduced in patients with cognitive impairment and apathy
  publication-title: Eur Psychiatry J Assoc Eur Psychiatr
  doi: 10.1016/j.eurpsy.2011.04.006
– ident: CR8
– ident: CR25
– year: 2018
  ident: CR27
  article-title: TATC: Predicting Alzheimer’s Disease with Actigraphy Data
  publication-title: KDD’ 18 24th ACM SIGKDD Int Conf Knowl Discov Data Min
– volume: 288
  start-page: 1475
  year: 2002
  end-page: 1483
  ident: CR5
  article-title: Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
  publication-title: JAMA
  doi: 10.1001/jama.288.12.1475
– volume: 14
  start-page: 639
  year: 2018
  end-page: 652
  ident: CR32
  article-title: Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic
  publication-title: Nat Rev Neurol
  doi: 10.1038/s41582-018-0079-7
– volume: 15
  start-page: 615
  year: 2019
  end-page: 624
  ident: CR12
  article-title: A randomized clinical trial to evaluate home-based assessment of people over 75 years old
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2019.01.007
– volume: 28
  start-page: 179.184
  year: 2013
  ident: CR18
  article-title: A behavioral task predicts conversion to mild cognitive impairment and Alzheimer’s disease
  publication-title: Am J Alzheimers Dis Other Demen
  doi: 10.1177/1533317512470484
– volume: 63
  start-page: 67.83
  year: 2017
  ident: CR20
  article-title: The Impact of Mild Cognitive Impairment on Gait and Balance: a Systematic Review and Meta-Analysis of Studies using Instrumented Assessment
  publication-title: Gerontology
  doi: 10.1159/000445831
– volume: 10
  start-page: 115
  year: 2014
  end-page: 131
  ident: CR33
  article-title: The future of blood-based biomarkers for Alzheimer’s disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2013.01.013
– volume: 275
  start-page: 214
  year: 2014
  end-page: 228
  ident: CR1
  article-title: Mild cognitive impairment: a concept in evolution
  publication-title: J Intern Med
  doi: 10.1111/joim.12190
– volume: 21
  start-page: 391.397
  year: 2013
  ident: CR22
  article-title: Phenotyping apathy in individuals with Alzheimer disease using functional principal component analysis
  publication-title: Am J Geriatr Psychiatry Off J Am Assoc Geriatr Psychiatry
– volume: 21
  start-page: e12785
  year: 2019
  ident: CR11
  article-title: Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review
  publication-title: J Med Internet Res
  doi: 10.2196/12785
– ident: CR3
– volume: 4
  start-page: 565
  year: 2018
  end-page: 574
  ident: CR15
  article-title: Online study partner-reported cognitive decline in the Brain Health Registry
  publication-title: Alzheimers Dement N Y N
– volume: 14
  start-page: 1063.1076
  year: 2018
  ident: CR13
  article-title: The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies
  publication-title: Alzheimers Dement J Alzheimers Assoc
– volume: 31
  start-page: 153.159
  year: 2018
  ident: CR19
  article-title: Sleep disturbance in mild cognitive impairment: a systematic review of recent findings
  publication-title: Curr Opin Psychiatry
  doi: 10.1097/YCO.0000000000000397
– ident: CR34
– ident: CR36
– volume: 9
  start-page: 44
  year: 2017
  ident: CR37
  article-title: Digitally translated Self-Administered Gerocognitive Examination (eSAGE): relationship with its validated paper version, neuropsychological evaluations, and clinical assessments
  publication-title: Alzheimers Res Ther
  doi: 10.1186/s13195-017-0269-3
– ident: CR28
– ident: CR26
– volume: 7
  start-page: 532
  year: 2011
  end-page: 539
  ident: CR4
  article-title: Neuropsychiatric symptoms in Alzheimer’s disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2011.05.2410
– ident: 10.14283/jpad.2020.22_bib30
– volume: 14
  start-page: 639
  year: 2018
  ident: 10.14283/jpad.2020.22_bib32
  article-title: Blood-based biomarkers for Alzheimer disease: mapping the road to the clinic
  publication-title: Nat Rev Neurol
  doi: 10.1038/s41582-018-0079-7
– volume: 14
  start-page: 535
  year: 2018
  ident: 10.14283/jpad.2020.22_bib2
  article-title: NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2018.02.018
– volume: 7
  start-page: 532
  year: 2011
  ident: 10.14283/jpad.2020.22_bib4
  article-title: Neuropsychiatric symptoms in Alzheimer's disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2011.05.2410
– volume: 14
  start-page: 1063.1076
  year: 2018
  ident: 10.14283/jpad.2020.22_bib13
  article-title: The Brain Health Registry: An internet-based platform for recruitment, assessment, and longitudinal monitoring of participants for neuroscience studies
  publication-title: Alzheimers Dement J Alzheimers Assoc
– ident: 10.14283/jpad.2020.22_bib28
– volume: 49
  start-page: 407
  year: 2016
  ident: 10.14283/jpad.2020.22_bib31
  article-title: Linguistic Features Identify Alzheimer's Disease in Narrative Speech
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-150520
– volume: 50
  start-page: 827
  year: 2016
  ident: 10.14283/jpad.2020.22_bib17
  article-title: Patients with Mild Alzheimer's Disease Fail When Using Their Working Memory: Evidence from the Eye Tracking Technique
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-150265
– volume: 52
  start-page: 509.517
  year: 2016
  ident: 10.14283/jpad.2020.22_bib24
  article-title: Development of a Proxy-Free Objective Assessment Tool of Instrumental Activities of Daily Living in Mild Cognitive Impairment Using Smart Home Technologies
  publication-title: J Alzheimers Dis JAD
– volume: 9
  start-page: 44
  year: 2017
  ident: 10.14283/jpad.2020.22_bib37
  article-title: Digitally translated Self-Administered Gerocognitive Examination (eSAGE): relationship with its validated paper version, neuropsychological evaluations, and clinical assessments
  publication-title: Alzheimers Res Ther
  doi: 10.1186/s13195-017-0269-3
– year: 2018
  ident: 10.14283/jpad.2020.22_bib27
  article-title: TATC: Predicting Alzheimer's Disease with Actigraphy Data
  publication-title: KDD' 18 24th ACM SIGKDD Int Conf Knowl Discov Data Min
– volume: 21
  start-page: e12785
  year: 2019
  ident: 10.14283/jpad.2020.22_bib11
  article-title: Current State of Digital Biomarker Technologies for Real-Life, Home-Based Monitoring of Cognitive Function for Mild Cognitive Impairment to Mild Alzheimer Disease and Implications for Clinical Care: Systematic Review
  publication-title: J Med Internet Res
  doi: 10.2196/12785
– volume: 21
  start-page: 391.397
  year: 2013
  ident: 10.14283/jpad.2020.22_bib22
  article-title: Phenotyping apathy in individuals with Alzheimer disease using functional principal component analysis
  publication-title: Am J Geriatr Psychiatry Off J Am Assoc Geriatr Psychiatry
– volume: 25
  start-page: 85.91
  year: 2011
  ident: 10.14283/jpad.2020.22_bib21
  article-title: Relationship between apathy and sleep disturbance in mild and moderate Alzheimer's disease: an actigraphic study
  publication-title: J Alzheimers Dis JAD
– volume: 10
  start-page: 115
  year: 2014
  ident: 10.14283/jpad.2020.22_bib33
  article-title: The future of blood-based biomarkers for Alzheimer's disease
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2013.01.013
– volume: 31
  start-page: 153.159
  year: 2018
  ident: 10.14283/jpad.2020.22_bib19
  article-title: Sleep disturbance in mild cognitive impairment: a systematic review of recent findings
  publication-title: Curr Opin Psychiatry
  doi: 10.1097/YCO.0000000000000397
– volume: 63
  start-page: 67.83
  year: 2017
  ident: 10.14283/jpad.2020.22_bib20
  article-title: The Impact of Mild Cognitive Impairment on Gait and Balance: a Systematic Review and Meta-Analysis of Studies using Instrumented Assessment
  publication-title: Gerontology
  doi: 10.1159/000445831
– volume: 275
  start-page: 214
  year: 2014
  ident: 10.14283/jpad.2020.22_bib1
  article-title: Mild cognitive impairment: a concept in evolution
  publication-title: J Intern Med
  doi: 10.1111/joim.12190
– volume: 15
  start-page: 615
  year: 2019
  ident: 10.14283/jpad.2020.22_bib12
  article-title: A randomized clinical trial to evaluate home-based assessment of people over 75 years old
  publication-title: Alzheimers Dement J Alzheimers Assoc
  doi: 10.1016/j.jalz.2019.01.007
– volume: 10
  start-page: 573.582
  year: 2018
  ident: 10.14283/jpad.2020.22_bib16
  article-title: Unsupervised online neuropsychological test performance for individuals with mild cognitive impairment and dementia: Results from the Brain Health Registry
  publication-title: Alzheimers Dement Amst Neth
– volume: 1
  start-page: 521
  year: 2015
  ident: 10.14283/jpad.2020.22_bib29
  article-title: Five year biomarker progression variability for Alzheimer's disease dementia prediction: Can a complex instrumental activities of daily living marker fill in the gaps?
  publication-title: Alzheimers Dement Amst Neth
  doi: 10.1016/j.dadm.2015.10.005
– volume: 17
  start-page: 669
  year: 2005
  ident: 10.14283/jpad.2020.22_bib9
  article-title: The Self Test: a screening tool for dementia requiring minimal supervision
  publication-title: Int Psychogeriatr
  doi: 10.1017/S1041610205001687
– volume: 28
  start-page: 179.184
  year: 2013
  ident: 10.14283/jpad.2020.22_bib18
  article-title: A behavioral task predicts conversion to mild cognitive impairment and Alzheimer's disease
  publication-title: Am J Alzheimers Dis Other Demen
  doi: 10.1177/1533317512470484
– volume: 288
  start-page: 1475
  year: 2002
  ident: 10.14283/jpad.2020.22_bib5
  article-title: Prevalence of neuropsychiatric symptoms in dementia and mild cognitive impairment: results from the cardiovascular health study
  publication-title: JAMA
  doi: 10.1001/jama.288.12.1475
– volume: 20
  start-page: 806.814
  year: 2012
  ident: 10.14283/jpad.2020.22_bib7
  article-title: Decreased daytime motor activity associated with apathy in Alzheimer disease: an actigraphic study
  publication-title: Am J Geriatr Psychiatry Off J Am Assoc Geriatr Psychiatry
– start-page: 10
  year: 2015
  ident: 10.14283/jpad.2020.22_bib23
  article-title: Use of High-Frequency In-Home Monitoring Data May Reduce Sample Sizes Needed in Clinical Trials
  publication-title: PLoS ONE
– volume: 4
  start-page: 565
  year: 2018
  ident: 10.14283/jpad.2020.22_bib15
  article-title: Online study partner-reported cognitive decline in the Brain Health Registry
  publication-title: Alzheimers Dement N Y N
  doi: 10.1016/j.trci.2018.09.008
– volume: 28
  start-page: 94
  year: 2013
  ident: 10.14283/jpad.2020.22_bib6
  article-title: Actigraphic daytime activity is reduced in patients with cognitive impairment and apathy
  publication-title: Eur Psychiatry J Assoc Eur Psychiatr
  doi: 10.1016/j.eurpsy.2011.04.006
– volume: 20
  start-page: 185
  year: 2010
  ident: 10.14283/jpad.2020.22_bib38
  article-title: The computerized self test (CST): an interactive, internet accessible cognitive screening test for dementia
  publication-title: J Alzheimers Dis JAD
  doi: 10.3233/JAD-2010-1354
SSID ssib050601372
ssib058688010
ssib053835554
ssib060159214
ssj0001916398
Score 2.3878052
SecondaryResourceType review_article
Snippet AbstractEmerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the...
Emerging digital tools have the potential to enable a new generation of qualitative and quantitative assessment of cognitive performance. Moreover, the...
SourceID hal
proquest
pubmed
crossref
springer
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 171
SubjectTerms Alzheimer Disease - diagnosis
Cognitive Dysfunction - diagnosis
Digital Technology
Direct-To-Consumer Screening and Testing - standards
Early Diagnosis
Geriatrics/Gerontology
Humans
Life Sciences
Mass Screening - instrumentation
Medicine
Medicine & Public Health
Mental Status and Dementia Tests - standards
Mobile Applications
Neurology
Reviews
Santé publique et épidémiologie
Title Early Detection of Mild Cognitive Impairment (MCI) in an At-Home Setting
URI https://www.clinicalkey.es/playcontent/1-s2.0-S2274580724004400
https://link.springer.com/article/10.14283/jpad.2020.22
https://www.ncbi.nlm.nih.gov/pubmed/32463070
https://www.proquest.com/docview/2407583192
https://hal.science/hal-04549431
Volume 7
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1LT9wwEB5RkKpeUKEPQgsyVdWH1NDYjh3vcRVAS9X0QpG4WYlji61QFrGhx_72zmSTBWlB4pAoihzLmfHjm4c_A3xEEFKW3pm4MmkVp8KpGFGIiTNnuDLcpzKQQ7_4pSfn6Y8LddEn0dBemPvxe-IC-_7nuiRCT5EcCpxpNxSXmjpvrvM7VwpCHDkyPYPmylePrTjPLin1cRVXrsREu6Xm5CVs9hiRjRdK3YI132zD86KPgr-CScdKzI582-VRNWwWWDG9qlk-5AKxUxzl0xvy_LEvRX76lU0bVjZs3MZ0Ljo7812682s4Pzn-nU_i_kSE2Cmh27hMKse18tqh3cZDqmtcrktZmyBLtHKzkCg0ONFYlmkiRzXnjrbySAQZIdTGJ_INrDezxu8AM8ElTkthnBcpaqXKRlopX2cm6MoLHcG3QWrW9XThdGrFlSWzgYRsSciWhGyFiODTsvj1gifjsYLZoAI7bP7E6crP-7Ezt9zOhU3smUCDWZkkoyzXFK8IPqDGlrUTL_Zk_NPSO-IRHCEU-ssjOBgUanGgUPSjbPzsdm7JdEXpIKKN4O1C08u6EFVqmvwi-Dyo3t6156Hf2H1yyXfwgp4W6WXvYb29ufV7CGTaar_rxvudGwDvxb_j_298634
linkProvider Springer Nature
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3LbtQwFL2CIgEbxLOE8jAI8ZAIJH7FsxwFqgxMumkrdWcljq0OqjJVJ-X7e28mmSINlVhkEzlWcm9sn2MfHwO8RxBSVd6ZuDayjiV3KkYUYuLMmVSZ1EsRaEK_PNDFsfx5ok4GEQ3thfl7_Z68wL79Pq_I0JMnXzn2tHckkmRS7uU6v55KQYgjJmZw0Nx66qYR5_YpSR-3ceXWmmg_1Ow_hAcDRmTTdVIfwS3fPoa75bAK_gSK3pWYffddr6Nq2TKwcnHWsHzUArEZtvLFBc38sU9lPvvMFi2rWjbtYjoXnR36Xu78FI73fxzlRTyciBA7xXUXV0ntUq28dsjb0iB1g8N1JRoTRIUsNwuJQsKJZFnIREyaNHW0lUcgyAihMT4Rz2CnXbb-OTATXOK04MZ5LjErdTbRSvkmM0HXnusIvoxRs26wC6dTK84s0QYKsqUgWwqy5TyCD5vi52ufjJsKZmMK7Lj5E7srvxrazsqmdsVtYg85EmZlkoxUrhKvCN5hxja1ky92MZ1bukc-ghOEQn_SCN6OCbXYUGj1o2r98nJlibpidBDRRrC7zvSmLkSVmjq_CD6OqbfX7_Ovz3jx3yXfwL3iqJzb-ezg1x7cp7trqdlL2OkuLv0rBDVd_br_pa8Aj5HsRQ
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1LT9wwEB5RKqFeqr4JfbmoKlQikNix41VPq9DVLmUREkXiZiWOrS5C2RUb-vs7k8dyWJB6yMVyomQmtr_PM_MZ4CuCkDx3VoeFToow4VaGiEJ0mFodSx27RHja0J-eqfFlcnIlrzbgR18L02S79yHJtqaBVJqq-mhR-maIk0LY0fUiJ5lPHh1ynH-fIklpYrSZyu43WLBJDHSnq7l212Pr0JM_lBC5jjbXIqXNAjR6Ac875MiGratfwoarXsHWtIuNv4Zxo1XMjl3dZFdVbO7ZdHZTsqzPEGITHPuzW9oPZPvTbPKdzSqWV2xYh3RaOrtwTRL0G7gc_fydjcPunITQSq7qMI8KGyvplEU2F_tElbiI56LUXuTIfVMfSaShSKFFEolBGceWCnwEQg_vS-0i8RY2q3nltoFpbyOrBNfW8QR9VaQDJaUrU-1V4bgK4KC3mrGdiDidZXFjiEyQkQ0Z2ZCRDecBfFt1X7TqGY91THsXmL4kFCcxt-xG1NLEZslNZC440mipo5RyXxO8AthFj62eTmrZ4-GpoTZSFxwgQPobB_Cld6jB4UMxkbxy87ulIUKL1kGcG8C71tOrZyHWVDQlBrDXu97cv89Dn7Hz3z0_w9b58cicTs5-vYdn1Njmn32Azfr2zn1EpFMXn5o_-h8gvfSM
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Early+Detection+of+Mild+Cognitive+Impairment+%28MCI%29+in+an+At-Home+Setting&rft.jtitle=The+Journal+of+Prevention+of+Alzheimer%27s+Disease&rft.au=Sabbagh%2C+Marwan+N.&rft.au=Boada%2C+M.&rft.au=Borson%2C+S.&rft.au=Doraiswamy%2C+P.M.&rft.date=2020-06-01&rft.issn=2274-5807&rft.volume=7&rft.issue=3&rft.spage=171&rft.epage=178&rft_id=info:doi/10.14283%2Fjpad.2020.22&rft.externalDBID=n%2Fa&rft.externalDocID=10_14283_jpad_2020_22
thumbnail_m http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F22745807%2FS2274580724X70235%2Fcov150h.gif