Unexpected effect of probiotics by Lactococcus lactis subsp. lactis against colitis induced by dextran sulfate sodium in mice

• Published in: Journal of Infection and Chemotherapy Vol. 26; no. 6; pp. 549 - 553
• Main Authors: Komaki, Shinichirou, Haque, Anwarul, Miyazaki, Haruko, Matsumoto, Tetsuya, Nakamura, Shigeki
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.06.2020; Elsevier BV
• Subjects: Animals; Colitis, Ulcerative; Colitis, Ulcerative - chemically induced; Colitis, Ulcerative - microbiology; Colitis, Ulcerative - pathology; Colon; Colon - immunology; Colon - pathology; Cytokines; Cytokines - blood; Dextran Sulfate; Dextran sulfate sodium-induced colitis; Disease Models, Animal; Female; Lactococcus lactis; Mice; Mice, Inbred C57BL; Probiotics; Probiotics - administration & dosage; Probiotics - adverse effects; Survival Analysis; Lactococcus lactis; Probiotics; Dextran sulfate sodium-induced colitis

Ulcerative colitis (UC) is a representative intestinal chronic inflammatory disease whose incidence is rapidly increasing worldwide. It was previously shown that some specific probiotics help to guard against UC. In this study, we analyzed the effect of Lactococcus lactis subsp. lactis JCM5805 (L. l...