Knee Cartilage Thickness, T1ρ and T2 Relaxation Time Are Related to Articular Cartilage Loading in Healthy Adults

• Published in: PloS one Vol. 12; no. 1; p. e0170002
• Main Authors: Van Rossom, Sam, Smith, Colin Robert, Zevenbergen, Lianne, Thelen, Darryl Gerard, Vanwanseele, Benedicte, Van Assche, Dieter, Jonkers, Ilse
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 01.01.2017; Public Library of Science (PLoS)
• Subjects: Adult; Adults; Arthritis; Biochemical composition; Biology and Life Sciences; Biomechanical Phenomena - physiology; Biomechanics; Cartilage; Cartilage (articular); Cartilage, Articular - anatomy & histology; Cartilage, Articular - diagnostic imaging; Cartilage, Articular - physiology; Collagen; Contact force; Contact pressure; Correlation; Data acquisition; Female; Femur; Gait; Healthy Volunteers; Humans; Impulses; Joint surgery; Kinesiology; Knee; Knee Joint - anatomy & histology; Knee Joint - diagnostic imaging; Knee Joint - physiology; Magnetic resonance imaging; Male; Mechanical engineering; Medicine and Health Sciences; Muscle Relaxation - physiology; NMR; Nuclear magnetic resonance; Organ Size; Physical Sciences; Pressure; Pressure distribution; Range of Motion, Articular; Rehabilitation; Relaxation time; Skin & tissue grafts; Stress analysis; Stress concentration; Time compression; Walking; Weight-Bearing - physiology; Young Adult

Cartilage is responsive to the loading imposed during cyclic routine activities. However, the local relation between cartilage in terms of thickness distribution and biochemical composition and the local contact pressure during walking has not been established. The objective of this study was to eva...