Use of gum arabic to improve the fabrication of chitosan–gelatin-based nanofibers for tissue engineering

• Published in: Carbohydrate Polymers Vol. 115; pp. 525 - 532
• Main Authors: Tsai, Ruei-Yi, Kuo, Ting-Yun, Hung, Shih-Chieh, Lin, Che-Min, Hsien, Tzu-Yang, Wang, Da-Ming, Hsieh, Hsyue-Jen
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 22.01.2015; Elsevier BV
• Subjects: Acetic Acid; Acetic Acid - chemistry; Cell Adhesion; Cell Proliferation; Cells, Cultured; Chitosan; Chitosan - chemistry; Cross-Linking Reagents; Cross-Linking Reagents - chemistry; crosslinking; Cytocompatibility; Electrospinning; Gelatin; Gelatin - chemistry; Glutaral; Glutaral - chemistry; glutaraldehyde; Gum Arabic; Gum Arabic - chemistry; Humans; Mesenchymal Stem Cells; Mesenchymal Stromal Cells - cytology; Mesenchymal Stromal Cells - physiology; methodology; Nanofibers; Nanofibers - chemistry; Polyvinyl Alcohol; Polyvinyl Alcohol - chemistry; Porosity; solvents; stem cells; Tensile Strength; Tissue Engineering; Viscosity; Viscosity; Electrospinning; Chitosan; Gum arabic; Cytocompatibility; Gelatin

•Use of gum arabic could produce a solution with high chitosan–gelatin content (16wt%).•No corrosive or expensive solvents were used.•The solution was electrospun into chitosan–gelatin-rich nanofibers.•The nanofibers were cytocompatible and thus suitable for use in tissue engineering.•A novel method...