(In)Consistencies in Responses to Sodium Bicarbonate Supplementation: A Randomised, Repeated Measures, Counterbalanced and Double-Blind Study

• Published in: PloS one Vol. 10; no. 11; p. e0143086
• Main Authors: Froio de Araujo Dias, Gabriela, da Eira Silva, Vinicius, de Salles Painelli, Vitor, Sale, Craig, Giannini Artioli, Guilherme, Gualano, Bruno, Saunders, Bryan
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 17.11.2015; Public Library of Science (PLoS)
• Subjects: Acid-Base Equilibrium; Adult; Amino acids; Bicarbonates; Bicycling; Blood; Body mass; Carbonates; Consistency; Cycles; Data collection; Dietary Supplements; Double-Blind Method; Double-blind studies; Exercise; Exercise Tolerance - drug effects; Humans; Hydrogen ions; Ingestion; Laboratories; Lactic acid; Lactic Acid - blood; Male; Males; Meta-analysis; Metabolism; Nutrition; pH effects; Physical education; Sodium; Sodium bicarbonate; Sodium Bicarbonate - administration & dosage; Studies; Supplements; Treatment Outcome; Within-subjects design; Brazil

Intervention studies do not account for high within-individual variation potentially compromising the magnitude of an effect. Repeat administration of a treatment allows quantification of individual responses and determination of the consistency of responses. We determined the consistency of metabol...