Clinical significance and immune infiltration analyses of a novel coagulation-related signature in ovarian cancer

• Published in: Cancer cell international Vol. 23; no. 1; pp. 1 - 232
• Main Authors: Yang, Jiani, Wang, Chao, Zhang, Yue, Cheng, Shanshan, Wu, Meixuan, Gu, Sijia, Xu, Shilin, Wu, Yongsong, Sheng, Jindan, Voon, Dominic Chih-Cheng, Wang, Yu
• Format: Journal Article
• Language: English
• Published: London BioMed Central 06.10.2023; BMC
• Subjects: Algorithms; Anticoagulants; Antigens; Cancer therapies; CD38 antigen; Chemotherapy; Clinical significance; Coagulation; Datasets; DNA microarrays; Genes; Genomes; Genomics; Immune microenvironment; Immunotherapy; Infiltration; Malignancy; Medical prognosis; Metastases; Microenvironments; Nomograms; Ovarian cancer; Patients; Prognosis; Prognosis signature; Software; Thrombosis; Transcriptomes; Tumors

Ovarian cancer (OV) is the most lethal gynecological malignancies worldwide. The coagulation cascade could induce tumor cell infiltration and contribute to OV progression. However, coagulation-related gene (CRG) signature for OV prognosis hasn’t been determined yet. In this study, we evaluated the p...