The Role of PPARγ in Advanced Glycation End Products-Induced Inflammatory Response in Human Chondrocytes - Ma, Chi; Zhang, Ying; Li, Yu-qing; Chen, Cheng; Cai, Wei; Zeng, Yue-lin (PloS one, 2015)
Keywords: Adult; Advanced glycosylation end products; Age; Arthritis; Biocompatibility; Biomedical materials; Cartilage, Articular - cytology; Cells, Cultured; Chondrocytes; Chondrocytes - drug effects; Chondrocytes - metabolism; Collagenase 3; Cytosol; Down-regulation; Female; Gene expression; Glycation End Products, Advanced - pharmacology; Glycosylation; Homeostasis; Human behavior; Humans; Immunoglobulins; Inflammation; Inflammation - chemically induced; Inflammation - metabolism; Inflammatory response; Inhibitors; Interleukin 1; Interleukin-1 - metabolism; JNK protein; Kinases; Male; MAP kinase; Matrix Metalloproteinase 13 - metabolism; NF-κB protein; Orthopedics; Osteoarthritis; Penicillin; Peroxisome proliferator-activated receptors; Pharmacology; Pioglitazone; PPAR gamma - agonists; PPAR gamma - metabolism; Proteins; Receptor mechanisms; Receptors; Signal transduction; Signaling; Thiazolidinediones - metabolism; Thiazolidinediones - pharmacology; Tumor Necrosis Factor-alpha - metabolism; Tumor necrosis factor-TNF; Tumor necrosis factor-α; Western blotting