Management of chronic Hepatitis C at a primary health clinic in the high-burden context of Karachi, Pakistan

• Published in: PloS one Vol. 12; no. 4; p. e0175562
• Main Authors: Capileno, Yuely A., Van den Bergh, Rafael, Donchunk, Dmytro, Hinderaker, Sven Gudmund, Hamid, Saeed, Auat, Rosa, Khalid, Gul Ghuttai, Fatima, Razia, Yaqoob, Aashifa, Van Overloop, Catherine
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 27.04.2017; Public Library of Science (PLoS)
• Subjects: Adult; Aged; Algorithms; Biology and life sciences; Blood platelets; Child; Child, Preschool; Chronic infection; Clinical outcomes; Cohort Studies; Communities; Cost of Illness; Diagnostic systems; Feasibility studies; Female; Genotype & phenotype; Genotypes; Health care; Hemoglobin; Hepatitis; Hepatitis C; Hepatitis C virus; Hepatitis C, Chronic - economics; Hepatitis C, Chronic - therapy; Hepatology; Humans; Infections; Interferon; Liver; Lung diseases; Male; Medicine and health sciences; Middle Aged; Pakistan; Patients; People and Places; Population; Primary care; Primary Health Care; Public health; Retrospective Studies; Ribavirin; Risk factors; Treatment Outcome; Tuberculosis; Urban areas; Urban populations; Pakistan; Islamabad Pakistan; Belgium; France; Karachi Pakistan

The burden of hepatitis C (HCV) infection in Pakistan is among the highest in the world, with a reported national HCV prevalence of 6.7% in 2014. In specific populations, such as in urban communities in Karachi, the prevalence is suspected to be higher. Interferon-free treatment for chronic HCV infe...