Spatial Patterning of Tissue Volume Loss in Schizophrenia Reflects Brain Network Architecture

• Published in: Biological psychiatry (1969) Vol. 87; no. 8; pp. 727 - 735
• Main Authors: Shafiei, Golia, Markello, Ross D., Makowski, Carolina, Talpalaru, Alexandra, Kirschner, Matthias, Devenyi, Gabriel A., Guma, Elisa, Hagmann, Patric, Cashman, Neil R., Lepage, Martin, Chakravarty, M. Mallar, Dagher, Alain, Mišić, Bratislav
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.04.2020
• Subjects: Adolescent; Adult; Anterior cingulate; Brain - diagnostic imaging; Connectome; Disease epicenter; Female; Gray Matter - diagnostic imaging; Humans; Intrinsic networks; Magnetic Resonance Imaging; Middle Aged; Psychiatric/Mental Health; Schizophrenia; Schizophrenia - diagnostic imaging; Ventral attention network; Young Adult; Schizophrenia; Anterior cingulate; Intrinsic networks; Ventral attention network; Connectome; Disease epicenter

There is growing recognition that connectome architecture shapes cortical and subcortical gray matter atrophy across a spectrum of neurological and psychiatric diseases. Whether connectivity contributes to tissue volume loss in schizophrenia in the same manner remains unknown. Here, we relate tissue...