Design of the Vitesse Intracranial Stent Study for Ischemic Therapy (VISSIT) Trial in Symptomatic Intracranial Stenosis

• Published in: Journal of stroke and cerebrovascular diseases Vol. 22; no. 7; pp. 1131 - 1139
• Main Authors: Zaidat, Osama O., Castonguay, Alicia C., Fitzsimmons, Brian-Fred, Woodward, Britton Keith, Wang, Zhigang, Killer-Oberpfalzer, Monika, Wakhloo, Ajay, Gupta, Rishi, Kirshner, Howard, Eliasziw, Misha, Thomas Megerian, J., Shetty, Sujith, Yoklavich Guilhermier, Meg, Barnwell, Stanley, Smith, Wade S., Gress, Daryl R.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2013
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; angioplasty; balloon-mounted stent; Cardiovascular; Clinical Protocols; clinical trial; Constriction, Pathologic - surgery; endovascular; Female; Humans; Intracranial Arteriosclerosis - complications; Intracranial Arteriosclerosis - surgery; intracranial stenosis; intracranial stent; ischemic stroke; Male; Middle Aged; Neurology; PHAROS stent; Research Design; Stents - adverse effects; stroke; Stroke - etiology; Stroke - prevention & control; transient ischemic attack; VISSIT; Vitesse stent; Vitesse stent; clinical trial; VISSIT; endovascular; intracranial stent; PHAROS stent; intracranial stenosis; transient ischemic attack; stroke; balloon-mounted stent; ischemic stroke; angioplasty

Patients with high-grade symptomatic intracranial stenosis (≥70%) have an increased risk of recurrent stroke despite medical treatment with antiplatelet or anticoagulant therapy. Intracranial stenting has been proposed as a viable treatment option for this high-risk patient population; however, eval...