Meta-analysis of genetic association studies

• Published in: Trends in genetics Vol. 20; no. 9; pp. 439 - 444
• Main Authors: Munafò, Marcus R., Flint, Jonathan
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.09.2004; Elsevier Science
• Subjects: Animals; Biological and medical sciences; Fundamental and applied biological sciences. Psychology; Genes - genetics; Genetic Techniques; Genetics; Genetics of eukaryotes. Biological and molecular evolution; Models, Genetic; Molecular and cellular biology; Multivariate Analysis; Personality - genetics; Genetics; Genetic determinism; Metaanalysis

Meta-analysis, a statistical tool for combining results across studies, is becoming popular as a method for resolving discrepancies in genetic association studies. Persistent difficulties in obtaining robust, replicable results in genetic association studies are almost certainly because genetic effe...