Comparison of non-invasive assessment of liver fibrosis in patients with alpha1-antitrypsin deficiency using magnetic resonance elastography (MRE), acoustic radiation force impulse (ARFI) Quantification, and 2D-shear wave elastography (2D-SWE)

• Published in: PloS one Vol. 13; no. 4; p. e0196486
• Main Authors: Reiter, Rolf, Wetzel, Martin, Hamesch, Karim, Strnad, Pavel, Asbach, Patrick, Haas, Matthias, Siegmund, Britta, Trautwein, Christian, Hamm, Bernd, Klatt, Dieter, Braun, Jürgen, Sack, Ingolf, Tzschätzsch, Heiko
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 26.04.2018; Public Library of Science (PLoS)
• Subjects: Acoustic resonance; Acoustics; Adult; Aged; alpha 1-Antitrypsin - blood; alpha 1-Antitrypsin - genetics; alpha 1-Antitrypsin Deficiency - complications; alpha 1-Antitrypsin Deficiency - diagnosis; alpha 1-Antitrypsin Deficiency - genetics; Bioengineering; Biology and Life Sciences; Body Mass Index; Case-Control Studies; Cirrhosis; College campuses; Correlation; Elasticity Imaging Techniques - methods; Engineering schools; Female; Fibrosis; Franklin, Benjamin (1706-1790); Gastroenterology; Genotype; Hepatocellular carcinoma; Hospitals; Humans; Identification methods; Intensive care; Liver; Liver - diagnostic imaging; Liver cancer; Liver cirrhosis; Liver Cirrhosis - complications; Liver Cirrhosis - diagnostic imaging; Liver Cirrhosis - pathology; Liver diseases; Magnetic resonance; Male; Medical diagnosis; Medicine and Health Sciences; Metabolic disorders; Methods; Middle Aged; Motivation; Patients; Physical Sciences; Prospective Studies; Radiation; Research and Analysis Methods; Resonance; Rheumatology; Shear; Systematic review; Ultrasonic imaging; Chicago Illinois; Aachen Germany; United States > US; Illinois; Germany

Although it has been known for decades that patients with alpha1-antitrypsin deficiency (AATD) have an increased risk of cirrhosis and hepatocellular carcinoma, limited data exist on non-invasive imaging-based methods for assessing liver fibrosis such as magnetic resonance elastography (MRE) and aco...