Role of UDP-Glucuronosyltransferase 1A1 in the Metabolism and Pharmacokinetics of Silymarin Flavonolignans in Patients with HCV and NAFLD - Xie, Ying; Miranda, Sonia; Hoskins, Janelle; Hawke, Roy (Molecules (Basel, Switzerland), 2017)
Keywords: Adult; Alleles; Female; Flavonolignans - administration & dosage; Flavonolignans - metabolism; Flavonolignans - pharmacokinetics; Genotype; Glucuronosyltransferase - genetics; HCV; Hepatitis C - blood; Hepatitis C - drug therapy; Hepatitis C - genetics; Hepatitis C virus; Humans; liver disease; Liver diseases; Male; Metabolism; Middle Aged; NAFLD; Non-alcoholic Fatty Liver Disease - blood; Non-alcoholic Fatty Liver Disease - drug therapy; Non-alcoholic Fatty Liver Disease - genetics; Pharmacogenomic Testing; pharmacokinetics; polymorphism; Polymorphism, Genetic; silybin A; silymarin; Silymarin - administration & dosage; Silymarin - metabolism; Silymarin - pharmacokinetics; UGT1A1; NAFLD; silymarin; UGT1A1; liver disease; pharmacokinetics; HCV; polymorphism; silybin A