Investigation of the role of SREBP-1c in the pathogenesis of HCV-related steatosis - McPherson, Stuart; Jonsson, Julie R.; Barrie, Helen D.; O’Rourke, Peter; Clouston, Andrew D.; Powell, Elizabeth E. (Journal of hepatology, 2008)
Keywords: Adult; Carrier Proteins - genetics; de novo lipogenesis; Fatty acid synthase; Fatty Acid Synthases - genetics; Fatty Liver - etiology; Fatty Liver - genetics; Fatty Liver - virology; Female; Gastroenterology and Hepatology; Gene Expression; Glycerol-3-phosphate acyltransferase; Glycerol-3-Phosphate O-Acyltransferase - genetics; Hepatitis C, Chronic - genetics; Hepatitis C, Chronic - pathology; Humans; Immunohistochemistry; Insulin resistance; Insulin Resistance - genetics; Lipogenesis - genetics; Male; Microsomal triglyceride transfer protein; RNA, Messenger - metabolism; Sterol Regulatory Element Binding Protein 1 - genetics; Sterol Regulatory Element Binding Protein 1 - metabolism; ACC; NAFLD; SREBP; Glycerol-3-phosphate acyltransferase; Microsomal triglyceride transfer protein; de novo lipogenesis; NASH; HuPO; ChREBP; NDL; FAS; AMPK; Insulin resistance; HCV; HOMA; qPCR; Fatty acid synthase; HBV; GPAT; GAPDH; BMI; non-alcoholic fatty liver disease; hepatitis B virus; AMP-activated protein kinase; semi-quantitative real-time polymerase chain reaction; hepatitis C virus; human acidic ribosomal protein; glyceraldehyde-3-phosphate dehydrogenase; non-diseased liver; sterol regulatory element binding protein; body mass index; glycerol-3-phosphate acyltransferase; acetyl CoA carboxylase; carbohydrate-responsive element binding protein; fatty acid synthase; homeostasis model of assessment; non-alcoholic steatohepatitis