Factors Impacting Early Mortality in Tuberculosis/HIV Patients: Differences between Subjects Naïve to and Previously Started on HAART

• Published in: PloS one Vol. 7; no. 9; p. e45704
• Main Authors: Schmaltz, Carolina Arana Stanis, Santoro-Lopes, Guilherme, Lourenço, Maria Cristina, Morgado, Mariza Gonçalves, Velasque, Luciane de Souza, Rolla, Valéria Cavalcanti
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 25.09.2012; Public Library of Science (PLoS)
• Subjects: Acquired immune deficiency syndrome; Adult; AIDS; Antiretroviral drugs; Antiretroviral Therapy, Highly Active - methods; Antitubercular Agents - therapeutic use; Biology; CD4 antigen; CD4-Positive T-Lymphocytes - cytology; Cell culture; Cell number; Cohort Studies; Diagnosis; Female; Follow-Up Studies; Highly active antiretroviral therapy; HIV; HIV Infections - complications; HIV Infections - mortality; Human immunodeficiency virus; Humans; Lymphocytes; Male; Medical diagnosis; Medicine; Middle Aged; Mortality; Multivariate Analysis; Patients; Proportional Hazards Models; Prospective Studies; Therapy; Treatment Outcome; Tuberculosis; Tuberculosis - complications; Tuberculosis - mortality; Brazil; Rio de Janeiro Brazil

Mortality among patients with tuberculosis (TB)/HIV is highest during the first few months of antituberculous therapy. The objective of this study was to assess the factors associated with early mortality among TB/HIV patients and whether these factors are similar for HAART naïve and those with prio...