Targeting neuroinflammation in Alzheimer's disease: from mechanisms to clinical applications

• Published in: Neural regeneration research Vol. 18; no. 4; pp. 708 - 715
• Main Authors: Si, Zi-Zhen, Zou, Chen-Jun, Mei, Xi, Li, Xiao-Fang, Luo, Hu, Shen, Yao, Hu, Jun, Li, Xing-Xing, Wu, Lun, Liu, Yu
• Format: Journal Article
• Language: English
• Published: Mumbai Wolters Kluwer India Pvt. Ltd 01.04.2023; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: Alzheimer's disease; alzheimer’s disease; astrocytes; immune signaling; inflammatory cytokines; microglia; neuroinflammation; neurotoxicity; therapeutic strategies; Pathogenesis; Review

Alzheimer's disease is characterized by sustained neuroinflammation leading to memory loss and cognitive decline. The past decade has witnessed tremendous efforts in Alzheimer's disease research; however, no effective treatment is available to prevent disease progression. An increasing bod...