Gut microbiome dysbiosis is associated with lumbar degenerative spondylolisthesis in symptomatic patients

• Published in: JOR-spine Vol. 7; no. 4; pp. e70005 - n/a
• Main Authors: Aboushaala, Khaled, Chee, Ana V., Adnan, Darbaz, Toro, Sheila J., Singh, Harmanjeet, Savoia, Andrew, Dhillon, Ekamjeet S., Yuh, Catherine, Dourdourekas, Jake, Patel, Ishani K., Vucicevic, Rajko, Espinoza‐Orias, Alejandro A., Martin, John T., Oh, Chundo, Keshavarzian, Ali, Albert, Hanne B., Karppinen, Jaro, Kocak, Mehmet, Wong, Arnold Y. L., Goldberg, Edward J., Phillips, Frank M., Colman, Matthew W., Williams, Frances M. K., Borgia, Jeffrey A., Naqib, Ankur, Green, Stefan J., Forsyth, Christopher B., An, Howard S., Samartzis, Dino
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.12.2024; Wiley
• Subjects: Antibiotics; Arthritis; Back pain; Bacteria; Classification; degeneration; Degenerative disc disease; Diabetes; disc; dysbiosis; Etiology; facets; Feces; Gut microbiota; imaging; Inflammation; Magnetic resonance imaging; microbiome; Microbiota; Pathology; Patients; spondylolisthesis; Vertebrae; spondylolisthesis; disc; imaging; microbiome; degeneration; dysbiosis; facets

Background Lumbar degenerative spondylolisthesis (LDS), characterized as degeneration of the intervertebral disc and structural changes of the facet joints, is a condition with varying degrees of instability that may lead to pain, canal stenosis, and subsequent surgical intervention. However, the et...