Approaches to interval mapping of QTL in a multigeneration pedigree: the example of porcine chromosome 4

• Published in: Animal genetics Vol. 33; no. 1; pp. 26 - 32
• Main Authors: Knott, S. A., Nyström, P. E., Andersson-Eklund, L., Stern, S., Marklund, L., Andersson, L., Haley, C. S.
• Format: Journal Article
• Language: English
• Published: Oxford UK Blackwell Science Ltd 01.02.2002; Wiley Subscription Services, Inc
• Subjects: Alleles; Animals; chromosome 4; Chromosome Mapping - veterinary; Chromosomes; Female; Genotype; Heterozygote; Inbreeding; interval mapping; Least-Squares Analysis; Male; Pedigree; piglets; pigs; production traits; quantitative trait loci; Quantitative Trait, Heritable; Regression Analysis; Stochastic Processes; Sus scrofa; Swine - genetics

Quantitative trait loci (QTLs) have been mapped in many studies of F2 populations derived from crosses between diverse lines. One approach to confirming these effects and improving the mapping resolution is genetic chromosome dissection through a backcrossing programme. Analysis by interval mapping...