The effect of antifungal combination on transcripts of a subset of drug-resistance genes in clinical isolates of Candida species induced biofilms

• Published in: Saudi pharmaceutical journal Vol. 23; no. 1; pp. 55 - 66
• Main Authors: Ibrahim, Nermin H., Melake, Nahla A., Somily, Ali M., Zakaria, Azza S., Baddour, Manal M., Mahmoud, Amany Z.
• Format: Journal Article
• Language: English
• Published: Saudi Arabia Elsevier B.V 01.01.2015
• Subjects: Antifungal; Biofilm; Candida spp; CDR1; KRE1; Original; SKN1; Candida spp; KRE1; Biofilm; Antifungal; SKN1; CDR1

Biofilm formation is often associated with increased Candida resistance toward antifungal agents. Therefore, the current study aimed to assess the incidence of biofilm formation among Candida isolates and to investigate the effect of high doses of fluconazole {FLC}, voriconazole {VOC} and amphoteric...