Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1 - Li, Chia-Wei; Lim, Seung-Oe; Chung, Ezra M.; Kim, Yong-Soo; Park, Andrew H.; Yao, Jun; Cha, Jong-Ho; Xia, Weiya; Chan, Li-Chuan; Kim, Taewan; Chang, Shih-Shin; Lee, Heng-Huan; et al. (Cancer cell, 2018)
Keywords: Animals; Antibodies, Monoclonal - pharmacology; antibody-drug conjugate; B3GNT3; Cell Line, Tumor; Female; glycosylation; Humans; immune checkpoint blockade; immunosuppression; immunotherapy; Lymphocytes, Tumor-Infiltrating - drug effects; Lymphocytes, Tumor-Infiltrating - immunology; Mice, Inbred BALB C; N-Acetylglucosaminyltransferases - drug effects; N-Acetylglucosaminyltransferases - metabolism; PD-1; PD-L1; Programmed Cell Death 1 Receptor - immunology; receptor internalization; TNBC; Triple Negative Breast Neoplasms - drug therapy; Triple Negative Breast Neoplasms - immunology; Triple Negative Breast Neoplasms - metabolism; antibody-drug conjugate; receptor internalization; immunotherapy; PD-L1; B3GNT3; glycosylation; immunosuppression; TNBC; PD-1; immune checkpoint blockade