Folate reference interval estimation in the Dutch general population

• Published in: Practical laboratory medicine Vol. 16; p. e00127
• Main Authors: Vos, Michel J., Joost van Pelt, L., Kok, Maarten B., Dijck-Brouwer, D.A. Janneke, Heiner-Fokkema, M. Rebecca, Dikkeschei, Lambert D., Kootstra-Ros, Jenny E.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2019; Elsevier
• Subjects: Folate; Folic acid; Homocysteine; One-carbon metabolism; Reference interval; One-carbon metabolism; Reference interval; Homocysteine; Folate; Folic acid

Folate functions as an enzyme co-factor within the one-carbon metabolic pathway, providing key metabolites required for DNA synthesis and methylation. Hence, insufficient intake of folate can negatively affect health. As correct interpretation of folate status is dependent on a well-established refe...