Health Related Quality of Life and Neurocognitive Outcomes in the First Year after Pediatric Acute Liver Failure

• Published in: The Journal of pediatrics Vol. 196; pp. 129 - 138.e3
• Main Authors: Sorensen, Lisa G., Neighbors, Katie, Hardison, Regina M., Loomes, Kathleen M., Varni, James W., Ng, Vicky L., Squires, Robert H., Alonso, Estella M., Bukauskas, Kathryn, Schulte, Madeline, Narkewicz, Michael R., Hite, Michelle, Rand, Elizabeth B., Piccoli, David, Kawchak, Deborah, Seidman, Christa, Romero, Rene, Karpen, Saul, de la Cruz-Tracy, Liezl, Hunt, Kelsey, Subbarao, Girish C., Klipsch, Ann, Munson, Sarah, Kelly, Susan, Rosenthal, Philip J., Fleck, Shannon, Leonis, Mike A., Bucuvalas, John, Horning, Tracie, Baez, Norberto Rodriguez, Montanye, Shirley, Cowie, Margaret, Horslen, Simon P., Murray, Karen, Young, Melissa, Nielson, Heather, Klein, Jani, Rudnick, David A., Shepherd, Ross W., Harris, Kathy, Karpen, Saul J., De La Torre, Alejandro, Dell Olio, Dominic, Kelly, Deirdre, Lloyd, Carla, Lobritto, Steven J., Bakhsh, Sumerah, Jonas, Maureen, Elifoson, Scott A., Raza, Roshan, Schwarz, Kathleen B., Karnsakul, Wikrom W., Alford, Mary Kay, Dhawan, Anil, Fitzpatrick, Emer, Kerkar, Nanda N., Haydel, Brandy, Narayanappa, Sreevidya, Lopez, M. James, Shieck, Victoria
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2018
• Subjects: Adolescent; Attention; Child; Child, Preschool; Cognition; cognition disorders; Cognitive Dysfunction - diagnosis; cognitive fatigue; Cross-Sectional Studies; Depression - complications; Executive Function; executive functioning; Fatigue; Female; Humans; Infant; Infant, Newborn; Intelligence Tests; Liver Failure, Acute - psychology; Liver Failure, Acute - therapy; Longitudinal Studies; Male; Mental Status and Dementia Tests; Motor Skills; pediatric liver disease; pediatric liver transplantation; Prospective Studies; Quality of Life; Stress Disorders, Post-Traumatic - complications; Treatment Outcome; Young Adult; APAP; cognitive fatigue; WPPSI-IV; CPT-II; PALFSG; VMI-6; PALF; PTSD; BRIEF; pediatric liver disease; K-CPT; ABAS-II; PedsQL MFS; WISC-IV; HRQoL; executive functioning; pediatric liver transplantation; CDI-2; HE; PedsQL; cognition disorders

To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). A longitudinal prospective study was conducted. At 6 and 12 months after PALF presentation, surveys of HRQoL were completed for 2- to 19-year-olds and executive fun...