Health Related Quality of Life and Neurocognitive Outcomes in the First Year after Pediatric Acute Liver Failure

To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). A longitudinal prospective study was conducted. At 6 and 12 months after PALF presentation, surveys of HRQoL were completed for 2- to 19-year-olds and executive fun...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of pediatrics Vol. 196; pp. 129 - 138.e3
Main Authors Sorensen, Lisa G., Neighbors, Katie, Hardison, Regina M., Loomes, Kathleen M., Varni, James W., Ng, Vicky L., Squires, Robert H., Alonso, Estella M., Bukauskas, Kathryn, Schulte, Madeline, Narkewicz, Michael R., Hite, Michelle, Rand, Elizabeth B., Piccoli, David, Kawchak, Deborah, Seidman, Christa, Romero, Rene, Karpen, Saul, de la Cruz-Tracy, Liezl, Hunt, Kelsey, Subbarao, Girish C., Klipsch, Ann, Munson, Sarah, Kelly, Susan, Rosenthal, Philip J., Fleck, Shannon, Leonis, Mike A., Bucuvalas, John, Horning, Tracie, Baez, Norberto Rodriguez, Montanye, Shirley, Cowie, Margaret, Horslen, Simon P., Murray, Karen, Young, Melissa, Nielson, Heather, Klein, Jani, Rudnick, David A., Shepherd, Ross W., Harris, Kathy, Karpen, Saul J., De La Torre, Alejandro, Dell Olio, Dominic, Kelly, Deirdre, Lloyd, Carla, Lobritto, Steven J., Bakhsh, Sumerah, Jonas, Maureen, Elifoson, Scott A., Raza, Roshan, Schwarz, Kathleen B., Karnsakul, Wikrom W., Alford, Mary Kay, Dhawan, Anil, Fitzpatrick, Emer, Kerkar, Nanda N., Haydel, Brandy, Narayanappa, Sreevidya, Lopez, M. James, Shieck, Victoria
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.05.2018
Subjects
Adolescent
Attention
Child
Child, Preschool
Cognition
cognition disorders
Cognitive Dysfunction - diagnosis
cognitive fatigue
Cross-Sectional Studies
Depression - complications
Executive Function
executive functioning
Fatigue
Female
Humans
Infant
Infant, Newborn
Intelligence Tests
Liver Failure, Acute - psychology
Liver Failure, Acute - therapy
Longitudinal Studies
Male
Mental Status and Dementia Tests
Motor Skills
pediatric liver disease
pediatric liver transplantation
Prospective Studies
Quality of Life
Stress Disorders, Post-Traumatic - complications
Treatment Outcome
Young Adult
APAP
cognitive fatigue
WPPSI-IV
CPT-II
PALFSG
VMI-6
PALF
PTSD
BRIEF
pediatric liver disease
K-CPT
ABAS-II
PedsQL MFS
WISC-IV
HRQoL
executive functioning
pediatric liver transplantation
CDI-2
HE
PedsQL
cognition disorders
Online AccessGet full text

Cover

Abstract To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). A longitudinal prospective study was conducted. At 6 and 12 months after PALF presentation, surveys of HRQoL were completed for 2- to 19-year-olds and executive functioning for ages 2-16 years. At 12 months, patients 3-16 years of age completed neurocognitive testing. HRQoL scores were compared with a healthy, matched sample. Neurocognitive scores were compared with norms; executive functioning scores were examined categorically. A total of 52 parent-report HRQoL surveys were completed at 6 months, 48 at 12 months; 25 patients completed neurocognitive testing. The median age at 6 months was 7.9 years (range 3.5-15.0), and final diagnosis was indeterminate for 46.2% (n = 24). Self and parent-report on Pediatric Quality of Life Inventory Generic and Multidimensional Fatigue scales fell below the healthy sample at 6 months and 12 months (almost all P < .001). Children reported lower mean scores on cognitive fatigue at 12 months (60.91 ± 22.99) compared with 6 months (73.61 ± 27.49, P = .006) . The distribution of Behavior Rating Inventory of Executive Function scores was shifted downward on parent-report (preschool) for all indices at 6 months (n = 14, P ≤ .003); Global Executive Composite and Emergent Metacognition at 12 months (n = 10, P = .03). Visual Motor Integration (VMI-6) Copying (mean = 90.3 ± 13.8, P = .0002) and VMI-6 Motor Coordination (mean = 85.1 ± 15.2 P = .0002) fell below norms, but full scale IQ (Wechsler Scales) and Attention (Conners' Continuous Performance Test) did not. Survivors of PALF appear to show deficits in motor skills, executive functioning, HRQoL, and evidence for worsening cognitive fatigue from 6 to 12 months following PALF presentation.
AbstractList To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). A longitudinal prospective study was conducted. At 6 and 12 months after PALF presentation, surveys of HRQoL were completed for 2- to 19-year-olds and executive functioning for ages 2-16 years. At 12 months, patients 3-16 years of age completed neurocognitive testing. HRQoL scores were compared with a healthy, matched sample. Neurocognitive scores were compared with norms; executive functioning scores were examined categorically. A total of 52 parent-report HRQoL surveys were completed at 6 months, 48 at 12 months; 25 patients completed neurocognitive testing. The median age at 6 months was 7.9 years (range 3.5-15.0), and final diagnosis was indeterminate for 46.2% (n = 24). Self and parent-report on Pediatric Quality of Life Inventory Generic and Multidimensional Fatigue scales fell below the healthy sample at 6 months and 12 months (almost all P < .001). Children reported lower mean scores on cognitive fatigue at 12 months (60.91 ± 22.99) compared with 6 months (73.61 ± 27.49, P = .006) . The distribution of Behavior Rating Inventory of Executive Function scores was shifted downward on parent-report (preschool) for all indices at 6 months (n = 14, P ≤ .003); Global Executive Composite and Emergent Metacognition at 12 months (n = 10, P = .03). Visual Motor Integration (VMI-6) Copying (mean = 90.3 ± 13.8, P = .0002) and VMI-6 Motor Coordination (mean = 85.1 ± 15.2 P = .0002) fell below norms, but full scale IQ (Wechsler Scales) and Attention (Conners' Continuous Performance Test) did not. Survivors of PALF appear to show deficits in motor skills, executive functioning, HRQoL, and evidence for worsening cognitive fatigue from 6 to 12 months following PALF presentation.
OBJECTIVETo determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF).STUDY DESIGNA longitudinal prospective study was conducted. At 6 and 12 months after PALF presentation, surveys of HRQoL were completed for 2- to 19-year-olds and executive functioning for ages 2-16 years. At 12 months, patients 3-16 years of age completed neurocognitive testing. HRQoL scores were compared with a healthy, matched sample. Neurocognitive scores were compared with norms; executive functioning scores were examined categorically.RESULTSA total of 52 parent-report HRQoL surveys were completed at 6 months, 48 at 12 months; 25 patients completed neurocognitive testing. The median age at 6 months was 7.9 years (range 3.5-15.0), and final diagnosis was indeterminate for 46.2% (n = 24). Self and parent-report on Pediatric Quality of Life Inventory Generic and Multidimensional Fatigue scales fell below the healthy sample at 6 months and 12 months (almost all P < .001). Children reported lower mean scores on cognitive fatigue at 12 months (60.91 ± 22.99) compared with 6 months (73.61 ± 27.49, P = .006) . The distribution of Behavior Rating Inventory of Executive Function scores was shifted downward on parent-report (preschool) for all indices at 6 months (n = 14, P ≤ .003); Global Executive Composite and Emergent Metacognition at 12 months (n = 10, P = .03). Visual Motor Integration (VMI-6) Copying (mean = 90.3 ± 13.8, P = .0002) and VMI-6 Motor Coordination (mean = 85.1 ± 15.2 P = .0002) fell below norms, but full scale IQ (Wechsler Scales) and Attention (Conners' Continuous Performance Test) did not.CONCLUSIONSSurvivors of PALF appear to show deficits in motor skills, executive functioning, HRQoL, and evidence for worsening cognitive fatigue from 6 to 12 months following PALF presentation.
Author Loomes, Kathleen M.
Montanye, Shirley
Ng, Vicky L.
Fleck, Shannon
Alford, Mary Kay
Kawchak, Deborah
Bucuvalas, John
Karpen, Saul J.
Karpen, Saul
Subbarao, Girish C.
Lopez, M. James
Kelly, Susan
Harris, Kathy
Jonas, Maureen
Horning, Tracie
Squires, Robert H.
Cowie, Margaret
Dhawan, Anil
Bakhsh, Sumerah
Romero, Rene
Klipsch, Ann
Rosenthal, Philip J.
Lloyd, Carla
Shepherd, Ross W.
Rudnick, David A.
Leonis, Mike A.
Hite, Michelle
Lobritto, Steven J.
Karnsakul, Wikrom W.
Kerkar, Nanda N.
Shieck, Victoria
Alonso, Estella M.
Schwarz, Kathleen B.
Haydel, Brandy
Murray, Karen
Kelly, Deirdre
Nielson, Heather
Baez, Norberto Rodriguez
Narayanappa, Sreevidya
Young, Melissa
Narkewicz, Michael R.
Fitzpatrick, Emer
Varni, James W.
Rand, Elizabeth B.
Seidman, Christa
Hunt, Kelsey
Schulte, Madeline
Dell Olio, Dominic
Horslen, Simon P.
Hardison, Regina M.
Elifoson, Scott A.
Klein, Jani
Sorensen, Lisa G.
Piccoli, David
De La Torre, Alejandro
Neighbors, Katie
de la Cruz-Tracy, Liezl
Bukauskas, Kathryn
Munson, Sarah
Raza, Roshan
AuthorAffiliation 1 Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; Child & Adolescent Psychiatry
5 Texas A&M University, College Station, TX, USA; Pediatrics
6 Hospital for Sick Children, University of Toronto, ON, Canada; Division of Paediatric Gastroenterology, Hepatology and Nutrition
4 University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Pediatrics
2 Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; Pediatrics
3 University of Pittsburgh, Pittsburgh, PA, USA; Epidemiology
7 University of Pittsburgh, Pittsburgh, PA, USA; Pediatrics
AuthorAffiliation_xml – name: 4 University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania; Division of Gastroenterology, Hepatology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, PA, USA; Pediatrics
– name: 7 University of Pittsburgh, Pittsburgh, PA, USA; Pediatrics
– name: 3 University of Pittsburgh, Pittsburgh, PA, USA; Epidemiology
– name: 6 Hospital for Sick Children, University of Toronto, ON, Canada; Division of Paediatric Gastroenterology, Hepatology and Nutrition
– name: 5 Texas A&M University, College Station, TX, USA; Pediatrics
– name: 1 Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; Child & Adolescent Psychiatry
– name: 2 Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, USA; Pediatrics
Author_xml – sequence: 1
  givenname: Lisa G.
  surname: Sorensen
  fullname: Sorensen, Lisa G.
  organization: Department of Child & Adolescent Psychiatry, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
– sequence: 2
  givenname: Katie
  surname: Neighbors
  fullname: Neighbors, Katie
  organization: Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
– sequence: 3
  givenname: Regina M.
  surname: Hardison
  fullname: Hardison, Regina M.
  organization: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA
– sequence: 4
  givenname: Kathleen M.
  surname: Loomes
  fullname: Loomes, Kathleen M.
  organization: Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, The Children's Hospital of Philadelphia, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
– sequence: 5
  givenname: James W.
  surname: Varni
  fullname: Varni, James W.
  organization: Department of Pediatrics and Department of Landscape Architecture and Urban Planning, Texas A&M University, College Station, TX
– sequence: 6
  givenname: Vicky L.
  surname: Ng
  fullname: Ng, Vicky L.
  organization: Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada
– sequence: 7
  givenname: Robert H.
  surname: Squires
  fullname: Squires, Robert H.
  organization: Department of Pediatrics, University of Pittsburgh, Pittsburgh, PA
– sequence: 8
  givenname: Estella M.
  surname: Alonso
  fullname: Alonso, Estella M.
  organization: Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
– sequence: 9
  givenname: Kathryn
  surname: Bukauskas
  fullname: Bukauskas, Kathryn
  organization: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
– sequence: 10
  givenname: Madeline
  surname: Schulte
  fullname: Schulte, Madeline
  organization: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
– sequence: 11
  givenname: Michael R.
  surname: Narkewicz
  fullname: Narkewicz, Michael R.
  organization: Children's Hospital Colorado, Aurora, CO
– sequence: 12
  givenname: Michelle
  surname: Hite
  fullname: Hite, Michelle
  organization: Children's Hospital Colorado, Aurora, CO
– sequence: 13
  givenname: Elizabeth B.
  surname: Rand
  fullname: Rand, Elizabeth B.
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 14
  givenname: David
  surname: Piccoli
  fullname: Piccoli, David
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 15
  givenname: Deborah
  surname: Kawchak
  fullname: Kawchak, Deborah
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 16
  givenname: Christa
  surname: Seidman
  fullname: Seidman, Christa
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 17
  givenname: Rene
  surname: Romero
  fullname: Romero, Rene
  organization: Emory University, Atlanta, GA
– sequence: 18
  givenname: Saul
  surname: Karpen
  fullname: Karpen, Saul
  organization: Emory University, Atlanta, GA
– sequence: 19
  givenname: Liezl
  surname: de la Cruz-Tracy
  fullname: de la Cruz-Tracy, Liezl
  organization: Emory University, Atlanta, GA
– sequence: 20
  givenname: Kelsey
  surname: Hunt
  fullname: Hunt, Kelsey
  organization: Hospital for Sick Children, Toronto, Ontario, Canada
– sequence: 21
  givenname: Girish C.
  surname: Subbarao
  fullname: Subbarao, Girish C.
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 22
  givenname: Ann
  surname: Klipsch
  fullname: Klipsch, Ann
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 23
  givenname: Sarah
  surname: Munson
  fullname: Munson, Sarah
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 24
  givenname: Susan
  surname: Kelly
  fullname: Kelly, Susan
  organization: University of California San Francisco, San Francisco, CA
– sequence: 25
  givenname: Philip J.
  surname: Rosenthal
  fullname: Rosenthal, Philip J.
  organization: University of California San Francisco, San Francisco, CA
– sequence: 26
  givenname: Shannon
  surname: Fleck
  fullname: Fleck, Shannon
  organization: University of California San Francisco, San Francisco, CA
– sequence: 27
  givenname: Mike A.
  surname: Leonis
  fullname: Leonis, Mike A.
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 28
  givenname: John
  surname: Bucuvalas
  fullname: Bucuvalas, John
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 29
  givenname: Tracie
  surname: Horning
  fullname: Horning, Tracie
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 30
  givenname: Norberto Rodriguez
  surname: Baez
  fullname: Baez, Norberto Rodriguez
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 31
  givenname: Shirley
  surname: Montanye
  fullname: Montanye, Shirley
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 32
  givenname: Margaret
  surname: Cowie
  fullname: Cowie, Margaret
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 33
  givenname: Simon P.
  surname: Horslen
  fullname: Horslen, Simon P.
  organization: University of Washington, Seattle, WA
– sequence: 34
  givenname: Karen
  surname: Murray
  fullname: Murray, Karen
  organization: University of Washington, Seattle, WA
– sequence: 35
  givenname: Melissa
  surname: Young
  fullname: Young, Melissa
  organization: University of Washington, Seattle, WA
– sequence: 36
  givenname: Heather
  surname: Nielson
  fullname: Nielson, Heather
  organization: University of Washington, Seattle, WA
– sequence: 37
  givenname: Jani
  surname: Klein
  fullname: Klein, Jani
  organization: University of Washington, Seattle, WA
– sequence: 38
  givenname: David A.
  surname: Rudnick
  fullname: Rudnick, David A.
  organization: Washington University, St. Louis, MO
– sequence: 39
  givenname: Ross W.
  surname: Shepherd
  fullname: Shepherd, Ross W.
  organization: Washington University, St. Louis, MO
– sequence: 40
  givenname: Kathy
  surname: Harris
  fullname: Harris, Kathy
  organization: Washington University, St. Louis, MO
– sequence: 41
  givenname: Saul J.
  surname: Karpen
  fullname: Karpen, Saul J.
  organization: Baylor College of Medicine, Houston, TX
– sequence: 42
  givenname: Alejandro
  surname: De La Torre
  fullname: De La Torre, Alejandro
  organization: Baylor College of Medicine, Houston, TX
– sequence: 43
  givenname: Dominic
  surname: Dell Olio
  fullname: Dell Olio, Dominic
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 44
  givenname: Deirdre
  surname: Kelly
  fullname: Kelly, Deirdre
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 45
  givenname: Carla
  surname: Lloyd
  fullname: Lloyd, Carla
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 46
  givenname: Steven J.
  surname: Lobritto
  fullname: Lobritto, Steven J.
  organization: Columbia University, New York, NY
– sequence: 47
  givenname: Sumerah
  surname: Bakhsh
  fullname: Bakhsh, Sumerah
  organization: Columbia University, New York, NY
– sequence: 48
  givenname: Maureen
  surname: Jonas
  fullname: Jonas, Maureen
  organization: Harvard Medical School, Boston, MA
– sequence: 49
  givenname: Scott A.
  surname: Elifoson
  fullname: Elifoson, Scott A.
  organization: Harvard Medical School, Boston, MA
– sequence: 50
  givenname: Roshan
  surname: Raza
  fullname: Raza, Roshan
  organization: Harvard Medical School, Boston, MA
– sequence: 51
  givenname: Kathleen B.
  surname: Schwarz
  fullname: Schwarz, Kathleen B.
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 52
  givenname: Wikrom W.
  surname: Karnsakul
  fullname: Karnsakul, Wikrom W.
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 53
  givenname: Mary Kay
  surname: Alford
  fullname: Alford, Mary Kay
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 54
  givenname: Anil
  surname: Dhawan
  fullname: Dhawan, Anil
  organization: King's College Hospital, London, United Kingdom
– sequence: 55
  givenname: Emer
  surname: Fitzpatrick
  fullname: Fitzpatrick, Emer
  organization: King's College Hospital, London, United Kingdom
– sequence: 56
  givenname: Nanda N.
  surname: Kerkar
  fullname: Kerkar, Nanda N.
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 57
  givenname: Brandy
  surname: Haydel
  fullname: Haydel, Brandy
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 58
  givenname: Sreevidya
  surname: Narayanappa
  fullname: Narayanappa, Sreevidya
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 59
  givenname: M. James
  surname: Lopez
  fullname: Lopez, M. James
  organization: University of Michigan, Ann Arbor, MI
– sequence: 60
  givenname: Victoria
  surname: Shieck
  fullname: Shieck, Victoria
  organization: University of Michigan, Ann Arbor, MI
BackLink https://www.ncbi.nlm.nih.gov/pubmed/29551316$$D View this record in MEDLINE/PubMed
BookMark eNp9UU1vEzEQtVARTQu_AAn5yGW3Y3u_fACpqgitFFFAcOBkOfa4cbRZB9sbqf8el5QKLpxGmnkfo_fOyMkUJiTkNYOaAesutvV2jzbVHNhQA6tBwDOyYCD7qhuEOCELAM4r0fTdKTlLaQsAsgF4QU65bFsmWLcg-2vUY97QrzjqjJZ-mfXo8z0Njq68Q6onSz_hHIMJd5PP_oD0ds4m7DBRP9G8Qbr0MWX6A3Wk2mWM9DNar3P0hl6aOWMROpTtUvtxjviSPHd6TPjqcZ6T78sP366uq9Xtx5ury1VlWt7mCkUnmWW2N-3gULStFOuer52AgUsO0kmrGXO8b-x66LTVwNCJfrDGtlw6Ls7J-6Pufl7v0BqcctSj2ke_0_FeBe3Vv5fJb9RdOKjiJJpGFIG3jwIx_JwxZbXzyeA46gnDnFSJvW1K2LIvUHGEmhhSiuiebBioh67UVv3u6oE0KGCqdFVYb_7-8Inzp5wCeHcEYMnp4DGqZDxOpsQb0WRlg_-vwS_ddKnc
CitedBy_id crossref_primary_10_1111_petr_14240
crossref_primary_10_1590_s0004_2803_202100000_40
crossref_primary_10_1007_s10880_022_09919_z
crossref_primary_10_1016_j_jpeds_2021_12_033
crossref_primary_10_3390_children8070571
crossref_primary_10_1002_lt_26500
crossref_primary_10_1097_MPG_0000000000002380
crossref_primary_10_1590_fm_2022_35138_0
crossref_primary_10_1111_petr_14686
crossref_primary_10_1590_fm_2022_35138
crossref_primary_10_1590_1519_6984_248778
crossref_primary_10_1097_MPG_0000000000003345
Cites_doi 10.3758/BF03193146
10.1097/PCC.0b013e3182712997
10.1002/lt.24406
10.1007/s11136-010-9823-1
10.1002/cncr.10428
10.1111/j.1600-6143.2010.03363.x
10.1111/j.1399-3046.2004.00126.x
10.1007/s11920-004-0048-2
10.1017/S0012162299001164
10.1097/00005650-200108000-00006
10.1002/pbc.24776
10.1080/13825585.2010.517826
10.1002/lt.21641
10.1055/s-2008-1073115
10.1097/MPG.0b013e31825f4c3e
10.1002/sim.4780090710
10.1097/MPG.0000000000000757
10.4103/0028-3886.72172
10.1111/j.1399-3046.2010.01453.x
10.1097/PCC.0b013e31826012b4
10.1016/j.jpeds.2009.08.048
10.1007/s11011-012-9361-3
10.1367/1539-4409(2003)003<0329:TPAAPP>2.0.CO;2
10.1097/MPG.0000000000000575
ContentType Journal Article
Contributor Montanye, Shirley
Leonis, Mike A
Fleck, Shannon
Alford, Mary Kay
Rudnick, David A
Kawchak, Deborah
Bucuvalas, John
Karpen, Saul
Kelly, Susan
Schwarz, Kathleen B
Harris, Kathy
Karpen, Saul J
Jonas, Maureen
Horning, Tracie
Cowie, Margaret
Dhawan, Anil
Bakhsh, Sumerah
Romero, Rene
Lopez, M James
Klipsch, Ann
Subbarao, Girish C
Lloyd, Carla
Horslen, Simon P
Rand, Elizabeth B
Hite, Michelle
Kerkar, Nanda N
Narkewicz, Michael R
Shieck, Victoria
Haydel, Brandy
Murray, Karen
Kelly, Deirdre
Nielson, Heather
Baez, Norberto Rodriguez
Narayanappa, Sreevidya
Young, Melissa
Fitzpatrick, Emer
Seidman, Christa
Hunt, Kelsey
Lobritto, Steven J
Schulte, Madeline
Rosenthal, Philip J
Dell Olio, Dominic
Karnsakul, Wikrom W
Shepherd, Ross W
Klein, Jani
Piccoli, David
Elifoson, Scott A
De La Torre, Alejandro
de la Cruz-Tracy, Liezl
Bukauskas, Kathryn
Munson, Sarah
Raza, Roshan
Contributor_xml – sequence: 1
  givenname: Kathryn
  surname: Bukauskas
  fullname: Bukauskas, Kathryn
  organization: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
– sequence: 2
  givenname: Madeline
  surname: Schulte
  fullname: Schulte, Madeline
  organization: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA
– sequence: 3
  givenname: Michael R
  surname: Narkewicz
  fullname: Narkewicz, Michael R
  organization: Children's Hospital Colorado, Aurora, CO
– sequence: 4
  givenname: Michelle
  surname: Hite
  fullname: Hite, Michelle
  organization: Children's Hospital Colorado, Aurora, CO
– sequence: 5
  givenname: Elizabeth B
  surname: Rand
  fullname: Rand, Elizabeth B
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 6
  givenname: David
  surname: Piccoli
  fullname: Piccoli, David
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 7
  givenname: Deborah
  surname: Kawchak
  fullname: Kawchak, Deborah
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 8
  givenname: Christa
  surname: Seidman
  fullname: Seidman, Christa
  organization: Children's Hospital of Philadelphia, Philadelphia, PA
– sequence: 9
  givenname: Rene
  surname: Romero
  fullname: Romero, Rene
  organization: Emory University, Atlanta, GA
– sequence: 10
  givenname: Saul
  surname: Karpen
  fullname: Karpen, Saul
  organization: Emory University, Atlanta, GA
– sequence: 11
  givenname: Liezl
  surname: de la Cruz-Tracy
  fullname: de la Cruz-Tracy, Liezl
  organization: Emory University, Atlanta, GA
– sequence: 12
  givenname: Kelsey
  surname: Hunt
  fullname: Hunt, Kelsey
  organization: Hospital for Sick Children, Toronto, Ontario, Canada
– sequence: 13
  givenname: Girish C
  surname: Subbarao
  fullname: Subbarao, Girish C
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 14
  givenname: Ann
  surname: Klipsch
  fullname: Klipsch, Ann
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 15
  givenname: Sarah
  surname: Munson
  fullname: Munson, Sarah
  organization: Indiana University Riley Hospital, Indianapolis, IN
– sequence: 16
  givenname: Susan
  surname: Kelly
  fullname: Kelly, Susan
  organization: University of California San Francisco, San Francisco, CA
– sequence: 17
  givenname: Philip J
  surname: Rosenthal
  fullname: Rosenthal, Philip J
  organization: University of California San Francisco, San Francisco, CA
– sequence: 18
  givenname: Shannon
  surname: Fleck
  fullname: Fleck, Shannon
  organization: University of California San Francisco, San Francisco, CA
– sequence: 19
  givenname: Mike A
  surname: Leonis
  fullname: Leonis, Mike A
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 20
  givenname: John
  surname: Bucuvalas
  fullname: Bucuvalas, John
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 21
  givenname: Tracie
  surname: Horning
  fullname: Horning, Tracie
  organization: University of Cincinnati, Cincinnati, OH
– sequence: 22
  givenname: Norberto Rodriguez
  surname: Baez
  fullname: Baez, Norberto Rodriguez
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 23
  givenname: Shirley
  surname: Montanye
  fullname: Montanye, Shirley
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 24
  givenname: Margaret
  surname: Cowie
  fullname: Cowie, Margaret
  organization: University of Texas Southwestern, Dallas, TX
– sequence: 25
  givenname: Simon P
  surname: Horslen
  fullname: Horslen, Simon P
  organization: University of Washington, Seattle, WA
– sequence: 26
  givenname: Karen
  surname: Murray
  fullname: Murray, Karen
  organization: University of Washington, Seattle, WA
– sequence: 27
  givenname: Melissa
  surname: Young
  fullname: Young, Melissa
  organization: University of Washington, Seattle, WA
– sequence: 28
  givenname: Heather
  surname: Nielson
  fullname: Nielson, Heather
  organization: University of Washington, Seattle, WA
– sequence: 29
  givenname: Jani
  surname: Klein
  fullname: Klein, Jani
  organization: University of Washington, Seattle, WA
– sequence: 30
  givenname: David A
  surname: Rudnick
  fullname: Rudnick, David A
  organization: Washington University, St. Louis, MO
– sequence: 31
  givenname: Ross W
  surname: Shepherd
  fullname: Shepherd, Ross W
  organization: Washington University, St. Louis, MO
– sequence: 32
  givenname: Kathy
  surname: Harris
  fullname: Harris, Kathy
  organization: Washington University, St. Louis, MO
– sequence: 33
  givenname: Saul J
  surname: Karpen
  fullname: Karpen, Saul J
  organization: Baylor College of Medicine, Houston, TX
– sequence: 34
  givenname: Alejandro
  surname: De La Torre
  fullname: De La Torre, Alejandro
  organization: Baylor College of Medicine, Houston, TX
– sequence: 35
  givenname: Dominic
  surname: Dell Olio
  fullname: Dell Olio, Dominic
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 36
  givenname: Deirdre
  surname: Kelly
  fullname: Kelly, Deirdre
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 37
  givenname: Carla
  surname: Lloyd
  fullname: Lloyd, Carla
  organization: Birmingham Children's Hospital, Birmingham, United Kingdom
– sequence: 38
  givenname: Steven J
  surname: Lobritto
  fullname: Lobritto, Steven J
  organization: Columbia University, New York, NY
– sequence: 39
  givenname: Sumerah
  surname: Bakhsh
  fullname: Bakhsh, Sumerah
  organization: Columbia University, New York, NY
– sequence: 40
  givenname: Maureen
  surname: Jonas
  fullname: Jonas, Maureen
  organization: Harvard Medical School, Boston, MA
– sequence: 41
  givenname: Scott A
  surname: Elifoson
  fullname: Elifoson, Scott A
  organization: Harvard Medical School, Boston, MA
– sequence: 42
  givenname: Roshan
  surname: Raza
  fullname: Raza, Roshan
  organization: Harvard Medical School, Boston, MA
– sequence: 43
  givenname: Kathleen B
  surname: Schwarz
  fullname: Schwarz, Kathleen B
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 44
  givenname: Wikrom W
  surname: Karnsakul
  fullname: Karnsakul, Wikrom W
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 45
  givenname: Mary Kay
  surname: Alford
  fullname: Alford, Mary Kay
  organization: Johns Hopkins University, Baltimore, MD
– sequence: 46
  givenname: Anil
  surname: Dhawan
  fullname: Dhawan, Anil
  organization: King's College Hospital, London, United Kingdom
– sequence: 47
  givenname: Emer
  surname: Fitzpatrick
  fullname: Fitzpatrick, Emer
  organization: King's College Hospital, London, United Kingdom
– sequence: 48
  givenname: Nanda N
  surname: Kerkar
  fullname: Kerkar, Nanda N
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 49
  givenname: Brandy
  surname: Haydel
  fullname: Haydel, Brandy
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 50
  givenname: Sreevidya
  surname: Narayanappa
  fullname: Narayanappa, Sreevidya
  organization: Mt. Sinai School of Medicine, New York, NY
– sequence: 51
  givenname: M James
  surname: Lopez
  fullname: Lopez, M James
  organization: University of Michigan, Ann Arbor, MI
– sequence: 52
  givenname: Victoria
  surname: Shieck
  fullname: Shieck, Victoria
  organization: University of Michigan, Ann Arbor, MI
Copyright 2018 Elsevier Inc.
Copyright © 2018 Elsevier Inc. All rights reserved.
Copyright_xml – notice: 2018 Elsevier Inc.
– notice: Copyright © 2018 Elsevier Inc. All rights reserved.
CorporateAuthor Pediatric Acute Liver Failure Study Group
CorporateAuthor_xml – name: Pediatric Acute Liver Failure Study Group
DBID CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
7X8
5PM
DOI 10.1016/j.jpeds.2018.01.030
DatabaseName Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
MEDLINE - Academic
PubMed Central (Full Participant titles)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
MEDLINE - Academic
DatabaseTitleList MEDLINE
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 1097-6833
EndPage 138.e3
ExternalDocumentID 10_1016_j_jpeds_2018_01_030
29551316
S0022347618300544
Genre Journal Article
Research Support, N.I.H., Extramural
GrantInformation_xml – fundername: National Institute of Diabetes and Digestive and Kidney Diseases
  grantid: U01 DK072146
  funderid: https://doi.org/10.13039/100000062
– fundername: NIDDK NIH HHS
  grantid: U01 DK072146
GroupedDBID ---
--K
--M
-ET
-RU
.1-
.55
.FO
.GJ
.XZ
.~1
0R~
123
1B1
1CY
1P~
1RT
1~.
1~5
354
3O-
4.4
41~
457
4G.
53G
5RE
5VS
7-5
85S
8P~
9JM
AACTN
AAEDT
AAEDW
AAEJM
AAIAV
AAIKC
AAIKJ
AAKOC
AALRI
AAMNW
AAOAW
AAQFI
AAQQT
AAQXK
AAWTL
AAXUO
AAYJJ
ABBQC
ABFNM
ABFRF
ABIVO
ABJNI
ABLJU
ABLVK
ABMAC
ABMZM
ABOCM
ABPPZ
ABXDB
ABYKQ
ACDAQ
ACGFO
ACGFS
ACNCT
ACRLP
ACRZS
ADBBV
ADEZE
ADMUD
AEBSH
AEFWE
AEKER
AENEX
AEVXI
AFDAS
AFFNX
AFKWA
AFRHN
AFTJW
AFXIZ
AGHFR
AGNAY
AGUBO
AGYEJ
AHHHB
AHPSJ
AI.
AIEXJ
AIKHN
AITUG
AJBFU
AJJEV
AJOXV
AJRQY
AJUYK
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ANZVX
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
BNPGV
C45
C5W
CAG
COF
CS3
DU5
EBS
EFJIC
EFLBG
EJD
EX3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
G8K
GBLVA
HEF
HMK
HMO
HVGLF
HZ~
IHE
J1W
K-O
KOM
L7B
LCYCR
M27
M32
M41
MO0
N4W
N9A
NEJ
NQ-
O-L
O9-
OAUVE
OB2
OBH
OH-
OHH
OHT
OT-
OVD
P-8
P-9
P2P
PC.
PQQKQ
Q38
R2-
RIG
ROL
RPZ
SAE
SDF
SEL
SES
SEW
SJN
SPCBC
SSH
SSZ
T5K
TEORI
TWZ
UGJ
UHB
UHS
UKR
UV1
VH1
VVN
WH7
WOW
WUQ
X7M
XCE
XFW
XOL
YCJ
YFH
YOC
YOJ
YQJ
YZZ
Z5R
ZA5
ZGI
ZQV
ZXP
ZY1
~G-
~KM
AAXKI
AFCTW
AFJKZ
AKRWK
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
ABDPE
ACRPL
ADNMO
CITATION
7X8
5PM
ID FETCH-LOGICAL-c525t-e3691d1d7c58fe35593b72bf30829209f9da11f274db86ada01ef378dcd529f23
IEDL.DBID .~1
ISSN 0022-3476
IngestDate Tue Sep 17 21:13:59 EDT 2024
Fri Oct 25 21:45:51 EDT 2024
Fri Dec 06 06:33:29 EST 2024
Wed Oct 16 00:50:59 EDT 2024
Fri Feb 23 02:29:26 EST 2024
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords APAP
cognitive fatigue
WPPSI-IV
CPT-II
PALFSG
VMI-6
PALF
PTSD
BRIEF
pediatric liver disease
K-CPT
ABAS-II
PedsQL MFS
WISC-IV
HRQoL
executive functioning
pediatric liver transplantation
CDI-2
HE
PedsQL
cognition disorders
Language English
License Copyright © 2018 Elsevier Inc. All rights reserved.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c525t-e3691d1d7c58fe35593b72bf30829209f9da11f274db86ada01ef378dcd529f23
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
List of additional members of the Pediatric Acute Liver Failure Study Group is available at www.jpeds.com (Appendix)
OpenAccessLink https://europepmc.org/articles/pmc5933443?pdf=render
PMID 29551316
PQID 2015409797
PQPubID 23479
ParticipantIDs pubmedcentral_primary_oai_pubmedcentral_nih_gov_5933443
proquest_miscellaneous_2015409797
crossref_primary_10_1016_j_jpeds_2018_01_030
pubmed_primary_29551316
elsevier_sciencedirect_doi_10_1016_j_jpeds_2018_01_030
PublicationCentury 2000
PublicationDate 2018-05-01
PublicationDateYYYYMMDD 2018-05-01
PublicationDate_xml – month: 05
  year: 2018
  text: 2018-05-01
  day: 01
PublicationDecade 2010
PublicationPlace United States
PublicationPlace_xml – name: United States
PublicationTitle The Journal of pediatrics
PublicationTitleAlternate J Pediatr
PublicationYear 2018
Publisher Elsevier Inc
Publisher_xml – name: Elsevier Inc
References Alonso, Limbers, Neighbors, Martz, Bucuvalas, Webb (bib0030) 2010; 156
Panepinto, Torres, Bendo, McCavit, Dinu, Sherman-Bien (bib0060) 2014; 61
Cole, Bucuvalas, Hornung, Krug, Ryckman, Atherton (bib0170) 2004; 8
Bemeur, Butterworth (bib0010) 2013; 28
Steinberg, Brymer, Decker, Pynoos (bib0120) 2004; 6
Almaas, Jensen, Loennecken, Tveter, Sanengen, Scholz (bib0180) 2015; 60
Holtzer, Shuman, Mahoney, Lipton, Verghese (bib0035) 2011; 18
Varni, Limbers, Sorensen, Neighbors, Martz, Bucuvalas (bib0065) 2011; 20
Gioia, Isquith, Guy, Kenworthy (bib0070) 2000
Guy, Isquith, Gioia (bib0080) 2004
Kovacs, Staff (bib0115) 2011
Sorensen, Neighbors, Zhang, Limbers, Varni, Ng (bib0040) 2015; 60
Beery, Buktenica, Beery (bib0100) 2010
Faul, Erdfelder, Lang, Buchner (bib0135) 2007; 39
Colville, Pierce (bib0160) 2013; 14
Dhawan (bib0015) 2008; 14
Wechsler (bib0090) 2003
Limbers, Neighbors, Martz, Bucuvalas, Webb, Varni (bib0155) 2011; 15
Squires (bib0020) 2008; 28
Varni, Seid, Kurtin (bib0045) 2001; 39
Feldman, Neighbors, Mukherjee, Rak, Varni, Alonso (bib0175) 2016; 22
Harrison, Oakland (bib0095) 2003
Gioia, Espy, Isquith (bib0075) 2005
Varni, Burwinkle, Katz, Meeske, Dickinson (bib0055) 2002; 94
Cunha, Mota, Teixeira-Pinto, Carvalho, Estrada, Marques (bib0165) 2013; 14
Conners (bib0110) 2004
Hochberg, Benjamini (bib0130) 1990; 9
Sorensen, Neighbors, Martz, Zelko, Bucuvalas, Alonso (bib0150) 2011; 11
Varni, Burwinkle, Seid, Skarr (bib0050) 2003; 3
Conners (bib0105) 2004
Meekin, Glasgow, McCusker, Rooney (bib0145) 1999; 41
Srivastava, Yadav, Borkar, Yadav, Yachha, Thomas (bib0025) 2012; 55
Wechsler (bib0085) 2012
Cohen (bib0125) 1988
Hegde, Sinha, Rao, Taly, Vasudev (bib0140) 2010; 58
Wechsler (10.1016/j.jpeds.2018.01.030_bib0085) 2012
Conners (10.1016/j.jpeds.2018.01.030_bib0105) 2004
Feldman (10.1016/j.jpeds.2018.01.030_bib0175) 2016; 22
Holtzer (10.1016/j.jpeds.2018.01.030_bib0035) 2011; 18
Varni (10.1016/j.jpeds.2018.01.030_bib0045) 2001; 39
Hochberg (10.1016/j.jpeds.2018.01.030_bib0130) 1990; 9
Colville (10.1016/j.jpeds.2018.01.030_bib0160) 2013; 14
Guy (10.1016/j.jpeds.2018.01.030_bib0080) 2004
Almaas (10.1016/j.jpeds.2018.01.030_bib0180) 2015; 60
Harrison (10.1016/j.jpeds.2018.01.030_bib0095) 2003
Cohen (10.1016/j.jpeds.2018.01.030_bib0125) 1988
Limbers (10.1016/j.jpeds.2018.01.030_bib0155) 2011; 15
Alonso (10.1016/j.jpeds.2018.01.030_bib0030) 2010; 156
Bemeur (10.1016/j.jpeds.2018.01.030_bib0010) 2013; 28
Meekin (10.1016/j.jpeds.2018.01.030_bib0145) 1999; 41
Dhawan (10.1016/j.jpeds.2018.01.030_bib0015) 2008; 14
Squires (10.1016/j.jpeds.2018.01.030_bib0020) 2008; 28
Wechsler (10.1016/j.jpeds.2018.01.030_bib0090) 2003
Cunha (10.1016/j.jpeds.2018.01.030_bib0165) 2013; 14
Varni (10.1016/j.jpeds.2018.01.030_bib0055) 2002; 94
Sorensen (10.1016/j.jpeds.2018.01.030_bib0040) 2015; 60
Gioia (10.1016/j.jpeds.2018.01.030_bib0075) 2005
Steinberg (10.1016/j.jpeds.2018.01.030_bib0120) 2004; 6
Hegde (10.1016/j.jpeds.2018.01.030_bib0140) 2010; 58
Kovacs (10.1016/j.jpeds.2018.01.030_bib0115) 2011
Sorensen (10.1016/j.jpeds.2018.01.030_bib0150) 2011; 11
Varni (10.1016/j.jpeds.2018.01.030_bib0050) 2003; 3
Srivastava (10.1016/j.jpeds.2018.01.030_bib0025) 2012; 55
Beery (10.1016/j.jpeds.2018.01.030_bib0100) 2010
Panepinto (10.1016/j.jpeds.2018.01.030_bib0060) 2014; 61
Varni (10.1016/j.jpeds.2018.01.030_bib0065) 2011; 20
Gioia (10.1016/j.jpeds.2018.01.030_bib0070) 2000
Faul (10.1016/j.jpeds.2018.01.030_bib0135) 2007; 39
Cole (10.1016/j.jpeds.2018.01.030_bib0170) 2004; 8
Conners (10.1016/j.jpeds.2018.01.030_bib0110) 2004
References_xml – year: 2012
  ident: bib0085
  article-title: Wechsler preschool and primary scale of intelligence — fourth edition technical and interpretative manual
  contributor:
    fullname: Wechsler
– volume: 156
  start-page: 270
  year: 2010
  end-page: 276
  ident: bib0030
  article-title: Cross-sectional analysis of health-related quality of life in pediatric liver transplant recipients
  publication-title: J Pediatr
  contributor:
    fullname: Webb
– volume: 61
  start-page: 171
  year: 2014
  end-page: 177
  ident: bib0060
  article-title: PedsQL Multidimensional Fatigue Scale in sickle cell disease: feasibility, reliability, and validity
  publication-title: Pediatr Blood Cancer
  contributor:
    fullname: Sherman-Bien
– volume: 15
  start-page: 245
  year: 2011
  end-page: 253
  ident: bib0155
  article-title: Health-related quality of life in pediatric liver transplant recipients compared with other chronic disease groups
  publication-title: Pediatr Transplant
  contributor:
    fullname: Varni
– year: 2003
  ident: bib0090
  article-title: Wechsler intelligence scale for children — fourth edition (WISC-IV).
  contributor:
    fullname: Wechsler
– volume: 39
  start-page: 175
  year: 2007
  end-page: 191
  ident: bib0135
  article-title: G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences
  publication-title: Behav Res Methods
  contributor:
    fullname: Buchner
– volume: 9
  start-page: 811
  year: 1990
  end-page: 818
  ident: bib0130
  article-title: More powerful procedures for multiple significance testing
  publication-title: Stat Med
  contributor:
    fullname: Benjamini
– volume: 28
  start-page: 145
  year: 2013
  end-page: 150
  ident: bib0010
  article-title: Liver-brain proinflammatory signaling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema
  publication-title: Metab Brain Dis
  contributor:
    fullname: Butterworth
– year: 2005
  ident: bib0075
  article-title: Behavior rating inventory of executive function — preschool version (BRIEF-P)
  contributor:
    fullname: Isquith
– volume: 55
  start-page: 580
  year: 2012
  end-page: 586
  ident: bib0025
  article-title: Serial evaluation of children with ALF with advanced MRI, serum proinflammatory cytokines, thiamine, and cognition assessment
  publication-title: J Pediatr Gastroenterol Nutr
  contributor:
    fullname: Thomas
– year: 2003
  ident: bib0095
  article-title: Adaptive behavior assessment system — second edition (ABAS-II)
  contributor:
    fullname: Oakland
– year: 2010
  ident: bib0100
  article-title: Beery-buktenica developmental test of visual-motor integration, sixth edition (Beery VMI)
  contributor:
    fullname: Beery
– volume: 94
  start-page: 2090
  year: 2002
  end-page: 2106
  ident: bib0055
  article-title: The PedsQL
  publication-title: Cancer
  contributor:
    fullname: Dickinson
– volume: 14
  start-page: e8
  year: 2013
  end-page: 15
  ident: bib0165
  article-title: Factors associated with health-related quality of life changes in survivors to pediatric intensive care
  publication-title: Pediatr Crit Care Med
  contributor:
    fullname: Marques
– volume: 3
  start-page: 329
  year: 2003
  end-page: 341
  ident: bib0050
  article-title: The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity
  publication-title: Ambul Pediatr
  contributor:
    fullname: Skarr
– volume: 41
  start-page: 549
  year: 1999
  end-page: 553
  ident: bib0145
  article-title: A long-term follow-up of cognitive, emotional, and behavioural sequelae to Reye syndrome
  publication-title: Dev Med Child Neurol
  contributor:
    fullname: Rooney
– volume: 28
  start-page: 153
  year: 2008
  end-page: 166
  ident: bib0020
  article-title: Acute liver failure in children
  publication-title: Semin Liver Dis
  contributor:
    fullname: Squires
– volume: 18
  start-page: 108
  year: 2011
  end-page: 128
  ident: bib0035
  article-title: Cognitive fatigue defined in the context of attention networks
  publication-title: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
  contributor:
    fullname: Verghese
– volume: 14
  start-page: e85
  year: 2013
  end-page: e92
  ident: bib0160
  article-title: Children's self-reported quality of life after intensive care treatment
  publication-title: Pediatr Crit Care Med
  contributor:
    fullname: Pierce
– volume: 6
  start-page: 96
  year: 2004
  end-page: 100
  ident: bib0120
  article-title: The University of California at Los Angeles post-traumatic stress disorder reaction index
  publication-title: Curr Psychiatry Rep
  contributor:
    fullname: Pynoos
– volume: 11
  start-page: 303
  year: 2011
  end-page: 311
  ident: bib0150
  article-title: Cognitive and academic outcomes after pediatric liver transplantation: Functional Outcomes Group (FOG) results
  publication-title: Am J Transplant
  contributor:
    fullname: Alonso
– volume: 39
  start-page: 800
  year: 2001
  end-page: 812
  ident: bib0045
  article-title: PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations
  publication-title: Med Care
  contributor:
    fullname: Kurtin
– year: 2004
  ident: bib0080
  article-title: Behavior rating inventory of executive function-self report version (BRIEF-SR)
  contributor:
    fullname: Gioia
– volume: 20
  start-page: 913
  year: 2011
  end-page: 921
  ident: bib0065
  article-title: PedsQL Cognitive Functioning Scale in pediatric liver transplant recipients: feasibility, reliability, and validity
  publication-title: Qual Life Res
  contributor:
    fullname: Bucuvalas
– year: 2011
  ident: bib0115
  article-title: Children's depression inventory 2nd edition (CDI-2)
  contributor:
    fullname: Staff
– volume: 14
  start-page: S80
  year: 2008
  end-page: S84
  ident: bib0015
  article-title: Etiology and prognosis of acute liver failure in children
  publication-title: Liver Transpl
  contributor:
    fullname: Dhawan
– year: 2004
  ident: bib0105
  article-title: Conners' continuous performance test II version 5
  contributor:
    fullname: Conners
– volume: 60
  start-page: 75
  year: 2015
  end-page: 83
  ident: bib0040
  article-title: Neuropsychological functioning and health-related quality of life: pediatric acute liver failure study group results
  publication-title: J Pediatr Gastroenterol Nutr
  contributor:
    fullname: Ng
– year: 2004
  ident: bib0110
  article-title: Conners' kiddie continuous performance test (K-CPT)
  contributor:
    fullname: Conners
– volume: 60
  start-page: 723
  year: 2015
  end-page: 728
  ident: bib0180
  article-title: Impaired motor competence in children with transplanted liver
  publication-title: J Pediatr Gastroenterol Nutr
  contributor:
    fullname: Scholz
– volume: 8
  start-page: 222
  year: 2004
  end-page: 227
  ident: bib0170
  article-title: Impact of liver transplantation on HRQoL in children less than 5 years old
  publication-title: Pediatr Transplant
  contributor:
    fullname: Atherton
– volume: 58
  start-page: 708
  year: 2010
  end-page: 713
  ident: bib0140
  article-title: Cognitive profile and structural findings in Wilson's disease: a neuropsychological and MRI-based study
  publication-title: Neurol India
  contributor:
    fullname: Vasudev
– volume: 22
  start-page: 495
  year: 2016
  end-page: 504
  ident: bib0175
  article-title: Impaired physical function following pediatric LT
  publication-title: Liver Transpl
  contributor:
    fullname: Alonso
– year: 2000
  ident: bib0070
  article-title: Behavior rating inventory of executive function
  contributor:
    fullname: Kenworthy
– year: 1988
  ident: bib0125
  article-title: Statistical power analysis for the behavioral sciences
  contributor:
    fullname: Cohen
– year: 2010
  ident: 10.1016/j.jpeds.2018.01.030_bib0100
  contributor:
    fullname: Beery
– volume: 39
  start-page: 175
  year: 2007
  ident: 10.1016/j.jpeds.2018.01.030_bib0135
  article-title: G*Power 3: a flexible statistical power analysis program for the social, behavioral, and biomedical sciences
  publication-title: Behav Res Methods
  doi: 10.3758/BF03193146
  contributor:
    fullname: Faul
– volume: 14
  start-page: e85
  year: 2013
  ident: 10.1016/j.jpeds.2018.01.030_bib0160
  article-title: Children's self-reported quality of life after intensive care treatment
  publication-title: Pediatr Crit Care Med
  doi: 10.1097/PCC.0b013e3182712997
  contributor:
    fullname: Colville
– volume: 22
  start-page: 495
  year: 2016
  ident: 10.1016/j.jpeds.2018.01.030_bib0175
  article-title: Impaired physical function following pediatric LT
  publication-title: Liver Transpl
  doi: 10.1002/lt.24406
  contributor:
    fullname: Feldman
– volume: 20
  start-page: 913
  year: 2011
  ident: 10.1016/j.jpeds.2018.01.030_bib0065
  article-title: PedsQL Cognitive Functioning Scale in pediatric liver transplant recipients: feasibility, reliability, and validity
  publication-title: Qual Life Res
  doi: 10.1007/s11136-010-9823-1
  contributor:
    fullname: Varni
– volume: 94
  start-page: 2090
  year: 2002
  ident: 10.1016/j.jpeds.2018.01.030_bib0055
  article-title: The PedsQLTM in pediatric cancer: reliability and validity of the Pediatric Quality of Life InventoryTM Generic Core Scales, Multidimensional Fatigue Scale, and Cancer Module
  publication-title: Cancer
  doi: 10.1002/cncr.10428
  contributor:
    fullname: Varni
– volume: 11
  start-page: 303
  year: 2011
  ident: 10.1016/j.jpeds.2018.01.030_bib0150
  article-title: Cognitive and academic outcomes after pediatric liver transplantation: Functional Outcomes Group (FOG) results
  publication-title: Am J Transplant
  doi: 10.1111/j.1600-6143.2010.03363.x
  contributor:
    fullname: Sorensen
– volume: 8
  start-page: 222
  year: 2004
  ident: 10.1016/j.jpeds.2018.01.030_bib0170
  article-title: Impact of liver transplantation on HRQoL in children less than 5 years old
  publication-title: Pediatr Transplant
  doi: 10.1111/j.1399-3046.2004.00126.x
  contributor:
    fullname: Cole
– volume: 6
  start-page: 96
  year: 2004
  ident: 10.1016/j.jpeds.2018.01.030_bib0120
  article-title: The University of California at Los Angeles post-traumatic stress disorder reaction index
  publication-title: Curr Psychiatry Rep
  doi: 10.1007/s11920-004-0048-2
  contributor:
    fullname: Steinberg
– year: 2004
  ident: 10.1016/j.jpeds.2018.01.030_bib0105
  contributor:
    fullname: Conners
– volume: 41
  start-page: 549
  year: 1999
  ident: 10.1016/j.jpeds.2018.01.030_bib0145
  article-title: A long-term follow-up of cognitive, emotional, and behavioural sequelae to Reye syndrome
  publication-title: Dev Med Child Neurol
  doi: 10.1017/S0012162299001164
  contributor:
    fullname: Meekin
– volume: 39
  start-page: 800
  year: 2001
  ident: 10.1016/j.jpeds.2018.01.030_bib0045
  article-title: PedsQL 4.0: reliability and validity of the Pediatric Quality of Life Inventory version 4.0 generic core scales in healthy and patient populations
  publication-title: Med Care
  doi: 10.1097/00005650-200108000-00006
  contributor:
    fullname: Varni
– volume: 61
  start-page: 171
  year: 2014
  ident: 10.1016/j.jpeds.2018.01.030_bib0060
  article-title: PedsQL Multidimensional Fatigue Scale in sickle cell disease: feasibility, reliability, and validity
  publication-title: Pediatr Blood Cancer
  doi: 10.1002/pbc.24776
  contributor:
    fullname: Panepinto
– volume: 18
  start-page: 108
  year: 2011
  ident: 10.1016/j.jpeds.2018.01.030_bib0035
  article-title: Cognitive fatigue defined in the context of attention networks
  publication-title: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
  doi: 10.1080/13825585.2010.517826
  contributor:
    fullname: Holtzer
– year: 2012
  ident: 10.1016/j.jpeds.2018.01.030_bib0085
  contributor:
    fullname: Wechsler
– year: 1988
  ident: 10.1016/j.jpeds.2018.01.030_bib0125
  contributor:
    fullname: Cohen
– year: 2003
  ident: 10.1016/j.jpeds.2018.01.030_bib0095
  contributor:
    fullname: Harrison
– volume: 14
  start-page: S80
  issue: Suppl 2
  year: 2008
  ident: 10.1016/j.jpeds.2018.01.030_bib0015
  article-title: Etiology and prognosis of acute liver failure in children
  publication-title: Liver Transpl
  doi: 10.1002/lt.21641
  contributor:
    fullname: Dhawan
– volume: 28
  start-page: 153
  year: 2008
  ident: 10.1016/j.jpeds.2018.01.030_bib0020
  article-title: Acute liver failure in children
  publication-title: Semin Liver Dis
  doi: 10.1055/s-2008-1073115
  contributor:
    fullname: Squires
– year: 2004
  ident: 10.1016/j.jpeds.2018.01.030_bib0110
  contributor:
    fullname: Conners
– volume: 55
  start-page: 580
  year: 2012
  ident: 10.1016/j.jpeds.2018.01.030_bib0025
  article-title: Serial evaluation of children with ALF with advanced MRI, serum proinflammatory cytokines, thiamine, and cognition assessment
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0b013e31825f4c3e
  contributor:
    fullname: Srivastava
– year: 2003
  ident: 10.1016/j.jpeds.2018.01.030_bib0090
  contributor:
    fullname: Wechsler
– year: 2011
  ident: 10.1016/j.jpeds.2018.01.030_bib0115
  contributor:
    fullname: Kovacs
– volume: 9
  start-page: 811
  year: 1990
  ident: 10.1016/j.jpeds.2018.01.030_bib0130
  article-title: More powerful procedures for multiple significance testing
  publication-title: Stat Med
  doi: 10.1002/sim.4780090710
  contributor:
    fullname: Hochberg
– volume: 60
  start-page: 723
  year: 2015
  ident: 10.1016/j.jpeds.2018.01.030_bib0180
  article-title: Impaired motor competence in children with transplanted liver
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0000000000000757
  contributor:
    fullname: Almaas
– year: 2000
  ident: 10.1016/j.jpeds.2018.01.030_bib0070
  contributor:
    fullname: Gioia
– volume: 58
  start-page: 708
  year: 2010
  ident: 10.1016/j.jpeds.2018.01.030_bib0140
  article-title: Cognitive profile and structural findings in Wilson's disease: a neuropsychological and MRI-based study
  publication-title: Neurol India
  doi: 10.4103/0028-3886.72172
  contributor:
    fullname: Hegde
– volume: 15
  start-page: 245
  year: 2011
  ident: 10.1016/j.jpeds.2018.01.030_bib0155
  article-title: Health-related quality of life in pediatric liver transplant recipients compared with other chronic disease groups
  publication-title: Pediatr Transplant
  doi: 10.1111/j.1399-3046.2010.01453.x
  contributor:
    fullname: Limbers
– year: 2005
  ident: 10.1016/j.jpeds.2018.01.030_bib0075
  contributor:
    fullname: Gioia
– volume: 14
  start-page: e8
  year: 2013
  ident: 10.1016/j.jpeds.2018.01.030_bib0165
  article-title: Factors associated with health-related quality of life changes in survivors to pediatric intensive care
  publication-title: Pediatr Crit Care Med
  doi: 10.1097/PCC.0b013e31826012b4
  contributor:
    fullname: Cunha
– volume: 156
  start-page: 270
  year: 2010
  ident: 10.1016/j.jpeds.2018.01.030_bib0030
  article-title: Cross-sectional analysis of health-related quality of life in pediatric liver transplant recipients
  publication-title: J Pediatr
  doi: 10.1016/j.jpeds.2009.08.048
  contributor:
    fullname: Alonso
– volume: 28
  start-page: 145
  year: 2013
  ident: 10.1016/j.jpeds.2018.01.030_bib0010
  article-title: Liver-brain proinflammatory signaling in acute liver failure: role in the pathogenesis of hepatic encephalopathy and brain edema
  publication-title: Metab Brain Dis
  doi: 10.1007/s11011-012-9361-3
  contributor:
    fullname: Bemeur
– volume: 3
  start-page: 329
  year: 2003
  ident: 10.1016/j.jpeds.2018.01.030_bib0050
  article-title: The PedsQL 4.0 as a pediatric population health measure: feasibility, reliability, and validity
  publication-title: Ambul Pediatr
  doi: 10.1367/1539-4409(2003)003<0329:TPAAPP>2.0.CO;2
  contributor:
    fullname: Varni
– volume: 60
  start-page: 75
  year: 2015
  ident: 10.1016/j.jpeds.2018.01.030_bib0040
  article-title: Neuropsychological functioning and health-related quality of life: pediatric acute liver failure study group results
  publication-title: J Pediatr Gastroenterol Nutr
  doi: 10.1097/MPG.0000000000000575
  contributor:
    fullname: Sorensen
– year: 2004
  ident: 10.1016/j.jpeds.2018.01.030_bib0080
  contributor:
    fullname: Guy
SSID ssj0009400
Score 2.3762033
Snippet To determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF). A longitudinal...
OBJECTIVETo determine health-related quality of life (HRQoL) and neurocognitive impairment in survivors of pediatric acute liver failure (PALF).STUDY DESIGNA...
SourceID pubmedcentral
proquest
crossref
pubmed
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 129
SubjectTerms Adolescent
Attention
Child
Child, Preschool
Cognition
cognition disorders
Cognitive Dysfunction - diagnosis
cognitive fatigue
Cross-Sectional Studies
Depression - complications
Executive Function
executive functioning
Fatigue
Female
Humans
Infant
Infant, Newborn
Intelligence Tests
Liver Failure, Acute - psychology
Liver Failure, Acute - therapy
Longitudinal Studies
Male
Mental Status and Dementia Tests
Motor Skills
pediatric liver disease
pediatric liver transplantation
Prospective Studies
Quality of Life
Stress Disorders, Post-Traumatic - complications
Treatment Outcome
Young Adult
Title Health Related Quality of Life and Neurocognitive Outcomes in the First Year after Pediatric Acute Liver Failure
URI https://dx.doi.org/10.1016/j.jpeds.2018.01.030
https://www.ncbi.nlm.nih.gov/pubmed/29551316
https://search.proquest.com/docview/2015409797
https://pubmed.ncbi.nlm.nih.gov/PMC5933443
Volume 196
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwELWqIiEuqECBLVAZiWND4684Pq4qVttCy4VK5WQ5sS3SQ3bVZg-98NuZcT5gW8SBY5JJZM2zx-P4-Q0hH3RdOae5z3QtfSaD5pkzgmWlL4R3tVBFhT_0zy-K5aU8u1JXO-RkPAuDtMoh9vcxPUXr4c7x4M3jddPgGV-Y2iQsw0uUXJeoCSpVjlUMPv78TfPAwt-TYjhYj8pDieN1vQ4eNbtZmbQ7kQr999npYfZ5n0T5x6y02CNPh3SSzvsWPyM7oX1OHp8PG-YvyLo_ZkQT5y142ktm3NFVpF-aGKhrPU36HBONiH7ddOCMcEublkJ2SBcNJIj0O4wImgqK06m6B53Xmy7Ah2A40IVrkOG-Ty4Xn76dLLOhyEJWK666LIjCMM-8rlUZA2QfRlSaVxFlbAzPTTTeMRZh8eqrsnDe5SxEoUtfe8VN5OIl2W1XbXhNqIlCAu5VXkQmIzeVkSaWzpXaKS8dn5Gj0bl23Wtp2JFkdm0TFhaxsDmzgMWMFCMAdqtLWIj2_37x_QiXhcGCOyCuDatNMlIo8GX0jLzq4Ztawg3WumHFjOgtYCcDFOLeftI2P5IgN_hMSCkO_rfBb8gTvOp5lG_JbnezCe8g1-mqw9SZD8mj-enn5cUvvr__5Q
link.rule.ids 230,314,780,784,885,4502,24116,27924,27925,45585,45679
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Nb9QwEB2VIgEXBAXKQgFX6pHQ9VccH6uK1QK77aWVyslyYltND9lVyR648NsZOx90AXHgGjuRNc8ej-M3bwCOVFVaq5jLVCVcJrximdWcZoXLubMVl3kZf-gvz_L5pfh8Ja924HTIhYm0yt73dz49eev-yXFvzeN1XcccX9zaBB7Diyi5LsQ9uC8kRr84qT_8-MXziJW_R8lw7D5IDyWS183auyjaTYsk3hm50H_fnv4MP39nUd7ZlmZP4HEfT5KTbshPYcc3e_Bg2d-YP4N1l2dEEunNO9JpZnwnq0AWdfDENo4kgY6RR0TONy1aw38jdUMwPCSzGiNE8hWXBEkVxclY3oOcVJvW44dwPZCZrSPF_Tlczj5enM6zvspCVkkm28zzXFNHnapkETyGH5qXipUh6thoNtVBO0tpwNOrK4vcOjulPnBVuMpJpgPjL2C3WTX-JRAduEDgy2keqAhMl1roUFhbKCudsGwC7wfjmnUnpmEGltmNSViYiIWZUoNYTCAfADBbc8Kgu__3i4cDXAZXS7wCsY1fbVInGRW-tJrAfgffOBKmY7Ebmk9AbQE7dohK3NstTX2dFLnRZlwI_up_B_wOHs4vlguz-HT25TU8ii0dqfIAdtvbjX-DgU9bvk0T-yezJwGR
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Health+Related+Quality+of+Life+and+Neurocognitive+Outcomes+in+the+First+Year+after+Pediatric+Acute+Liver+Failure&rft.jtitle=The+Journal+of+pediatrics&rft.au=Sorensen%2C+Lisa+G.&rft.au=Neighbors%2C+Katie&rft.au=Hardison%2C+Regina+M.&rft.au=Loomes%2C+Kathleen+M.&rft.date=2018-05-01&rft.issn=0022-3476&rft.volume=196&rft.spage=129&rft.epage=138.e3&rft_id=info:doi/10.1016%2Fj.jpeds.2018.01.030&rft.externalDBID=n%2Fa&rft.externalDocID=10_1016_j_jpeds_2018_01_030
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0022-3476&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0022-3476&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0022-3476&client=summon