Eyeglasses-based tear biosensing system: Non-invasive detection of alcohol, vitamins and glucose

• Published in: Biosensors & bioelectronics Vol. 137; pp. 161 - 170
• Main Authors: Sempionatto, Juliane R., Brazaca, Laís Canniatti, García-Carmona, Laura, Bolat, Gulcin, Campbell, Alan S., Martin, Aida, Tang, Guangda, Shah, Rushabh, Mishra, Rupesh K., Kim, Jayoung, Zucolotto, Valtencir, Escarpa, Alberto, Wang, Joseph
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 15.07.2019
• Subjects: Alcohol; alcohol drinking; alcohol oxidase; alcohols; Alcohols - chemistry; Alcohols - isolation & purification; biomarkers; Biosensing Techniques; biosensors; Electrochemical sensor; electrochemistry; Eyeglasses; eyes; Glucose; Glucose - chemistry; Glucose - isolation & purification; Humans; monitoring; Monitoring, Physiologic; nutrients; Tears; Tears - chemistry; Vitamins; Vitamins - chemistry; Vitamins - isolation & purification; Wearable Electronic Devices; Wearable sensor; Alcohol; Glucose; Wearable sensor; Electrochemical sensor; Tears; Vitamins

We report on a wearable tear bioelectronic platform, integrating a microfluidic electrochemical detector into an eyeglasses nose-bridge pad, for non-invasive monitoring of key tear biomarkers. The alcohol-oxidase (AOx) biosensing fluidic system allowed real-time tear collection and direct alcohol me...