Supervised reconstruction of biological networks with local models

• Published in: Bioinformatics Vol. 23; no. 13; pp. i57 - i65
• Main Authors: Bleakley, Kevin, Biau, Gérard, Vert, Jean-Philippe
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.07.2007; Oxford Publishing Limited (England); Oxford University Press (OUP)
• Subjects: Algorithms; Artificial Intelligence; Bioinformatics; Computer Science; Computer Simulation; Life Sciences; Models, Biological; Pattern Recognition, Automated; Pattern Recognition, Automated - methods; Protein Interaction Mapping; Protein Interaction Mapping - methods; Proteome; Proteome - metabolism; Quantitative Methods; Signal Transduction; Signal Transduction - physiology

Motivation: Inference and reconstruction of biological networks from heterogeneous data is currently an active research subject with several important applications in systems biology. The problem has been attacked from many different points of view with varying degrees of success. In particular, pre...