Receptor for Advanced Glycation End Products (RAGE) and Mechanisms and Therapeutic Opportunities in Diabetes and Cardiovascular Disease: Insights From Human Subjects and Animal Models

• Published in: Frontiers in cardiovascular medicine Vol. 7; p. 37
• Main Authors: Egaña-Gorroño, Lander, López-Díez, Raquel, Yepuri, Gautham, Ramirez, Lisa S., Reverdatto, Sergey, Gugger, Paul F., Shekhtman, Alexander, Ramasamy, Ravichandran, Schmidt, Ann Marie
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 10.03.2020
• Subjects: cardiovascular disease; Cardiovascular Medicine; diabetes; DIAPH1; obesity; peripheral arterial disease; RAGE; DIAPH1; cardiovascular disease; peripheral arterial disease; RAGE; diabetes; obesity

Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide less benefit for protection from cardiovascular d...