Evidence for altered brain reactivity to norepinephrine in Veterans with a history of traumatic stress

• Published in: Neurobiology of stress Vol. 8; pp. 103 - 111
• Main Authors: Hendrickson, Rebecca C., Raskind, Murray A., Millard, Steven P., Sikkema, Carl, Terry, Garth E., Pagulayan, Kathleen F., Li, Ge, Peskind, Elaine R.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.02.2018; Elsevier
• Subjects: Cerebrospinal fluid (CSF); Noradrenergic system; Original; Posttraumatic stress disorder (PTSD); Prazosin; Trauma; Veterans; Prazosin; Cerebrospinal fluid (CSF); Posttraumatic stress disorder (PTSD); Veterans; Trauma; Noradrenergic system

Increases in the quantity or impact of noradrenergic signaling have been implicated in the pathophysiology of posttraumatic stress disorder (PTSD). This increased signaling may result from increased norepinephrine (NE) release, from altered brain responses to NE, or from a combination of both factor...