A bacterial type III effector hijacks plant ubiquitin proteases to evade degradation

• Published in: PLoS pathogens Vol. 21; no. 1; p. e1012882
• Main Authors: Yu, Wenjia, Li, Meng, Wang, Wenjun, Zhuang, Haiyan, Luo, Jiamin, Sang, Yuying, Segonzac, Cecile, Macho, Alberto P.
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 22.01.2025; Public Library of Science (PLoS)
• Subjects: Bacterial diseases of plants; Bacterial proteins; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Biology and Life Sciences; Host-Pathogen Interactions; Microbiological research; Physiological aspects; Plant Diseases - microbiology; Plant Immunity; Plant Proteins - metabolism; Proteolysis; Ralstonia solanacearum - metabolism; Ralstonia solanacearum - pathogenicity; Research and Analysis Methods; Type III Secretion Systems - metabolism; Ubiquitin-proteasome system; Ubiquitin-Specific Proteases - metabolism; China

Gram-negative bacterial pathogens inject effector proteins inside plant cells using a type III secretion system. These effectors manipulate plant cellular functions and suppress the plant immune system in order to promote bacterial proliferation. Despite the fact that bacterial effectors are exogeno...