Ethnic differences in osteocalcin γ-carboxylation, plasma phylloquinone (vitamin K1) and apolipoprotein E genotype

• Published in: European journal of clinical nutrition Vol. 59; no. 1; pp. 72 - 81
• Main Authors: Beavan, S.R, Prentice, A, Stirling, D.M, Dibba, B, Yan, L, Harrington, D.J, Shearer, M.J
• Format: Journal Article
• Language: English
• Published: Basingstoke Nature Publishing 2005; Nature Publishing Group
• Subjects: Adult; Aged; Antifibrinolytic Agents - blood; apolipoproteins; Apolipoproteins E - genetics; Biological and medical sciences; Blood; blood serum; carboxylation; China - ethnology; Clinical nutrition; Comparative analysis; Cross-Sectional Studies; Diseases of the osteoarticular system; England - ethnology; Epidemiology; Ethnicity; Female; Gambia - ethnology; Genotype; Humans; Medical sciences; menopause; Middle Aged; Minority & ethnic groups; nationalities and ethnic groups; nutritional status; osteocalcin; Osteocalcin - blood; Osteocalcin - metabolism; osteoporosis; Osteoporosis, Postmenopausal - epidemiology; Osteoporosis, Postmenopausal - ethnology; Osteoporosis, Postmenopausal - metabolism; Osteoporosis. Osteomalacia. Paget disease; phylloquinone; Plasma; Postmenopause - ethnology; Postmenopause - metabolism; Premenopause - ethnology; Premenopause - metabolism; Proteins; Risk Factors; Vitamin K 1 - administration & dosage; Vitamin K 1 - blood; Vitamins; Women; China; England; Gambia; Human; Osteocalcin; apoE genotype; ethnic; Nutrition; Diseases of the osteoarticular system; Genotype; E-Vitamins; γ-carboxylation; Ethnic group; Blood plasma; Osteoporosis; Apolipoprotein E; Carboxylation; Female; Phylloquinone; Public health; Comparative study; Vitamin K

Objective: To investigate plasma osteocalcin gamma-carboxylation and its relationship to plasma phylloquinone concentration and apolipoprotein E (apoE) genotype in women from three ethnic groups with differing osteoporotic fracture risk. Design and subjects: Fasted blood samples were collected from...