Left ventricular global longitudinal strain in identifying subclinical myocardial dysfunction among patients hospitalized with COVID-19

• Published in: International journal of cardiology. Heart & vasculature Vol. 32; p. 100719
• Main Authors: Shmueli, Hezzy, Shah, Maulin, Ebinger, Joseph E., Nguyen, Long-Co, Chernomordik, Fernando, Flint, Nir, Botting, Patrick, Siegel, Robert J.
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.02.2021; Elsevier
• Subjects: COVID-19; Echocardiography; Global longitudinal strain; Original Paper; CRP; T2DM; Echocardiography; HTN; TTE; RV; BNP; LVEF; ECG; SARS; Global longitudinal strain; LV; LV-GLS; VTI; TAPSE; LVOT; IL-6; COVID-19; LDH; LA; AV; ICU; CMRI; COPD; BNP, B-type natriuretic peptide; LVEF, left ventricular ejection fraction; HTN, hypertension; COPD, chronic obstructive pulmonary disease; VTI, velocity-time integral; AV, atrioventricular; LV-GLS, left ventricular global longitudinal strain; CMRI, cardiac magnetic resonance imaging; IL-6, interleukin-6; ECG, electrocardiogram; T2DM, type-2 diabetes mellitus; ICU, intensive care unit; LV, left ventricle; TTE, transthoracic echocardiogram; LA, left atrium; LDH, lactate dehydrogenase; LVOT, left ventricular outflow tract; SARS, severe acute respiratory syndrome; TAPSE, tricuspid annular plane systolic excursion; RV, right ventricle; COVID-19, coronavirus disease 2019; CRP, C-reactive protein

•Acute cardiac injury (elevated Troponin) ranges from 8 to 28% in COVID-19 patients.•Standard overt cardiac dysfunction in TTE among COVID-19 patients is uncommon.•However, signs of subclinical myocardial dysfunction by GLS is prevalent. The incidence of acute cardiac injury in COVID-19 patients is...