DNA Repair Profiling Reveals Nonrandom Outcomes at Cas9-Mediated Breaks
The repair outcomes at site-specific DNA double-strand breaks (DSBs) generated by the RNA-guided DNA endonuclease Cas9 determine how gene function is altered. Despite the widespread adoption of CRISPR-Cas9 technology to induce DSBs for genome engineering, the resulting repair products have not been...
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Published in | Molecular cell Vol. 63; no. 4; pp. 633 - 646 |
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Main Authors | , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Elsevier Inc
18.08.2016
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Subjects | |
Online Access | Get full text |
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