Diabetes mellitus and white matter hyperintensity

• Published in: Geriatrics & gerontology international Vol. 15; no. S1; pp. 34 - 42
• Main Authors: Tamura, Yoshiaki, Araki, Atsushi
• Format: Journal Article
• Language: English
• Published: Japan Blackwell Publishing Ltd 01.12.2015
• Subjects: Aged; Aged, 80 and over; Aging - physiology; Brain; Brain Diseases - diagnosis; Brain Diseases - epidemiology; Comorbidity; Cross-Sectional Studies; deep white matter hyperintensity; Diabetes; diabetes mellitus; Diabetes Mellitus - diagnosis; Diabetes Mellitus - epidemiology; Diffusion Magnetic Resonance Imaging - methods; Disease Progression; Female; Geriatric Assessment - methods; geriatric syndrome; Gerontology; Humans; Hypertension; Hypertension - physiopathology; Incidence; Insulin Resistance - physiology; Leukoaraiosis - pathology; Leukoaraiosis - physiopathology; Male; Neurology; paraventricular leukoaraiosis; Prospective Studies; Risk Assessment; Risk factors; White Matter - pathology; White Matter - physiopathology; white matter hyperintensity; geriatric syndrome; diabetes mellitus; paraventricular leukoaraiosis; deep white matter hyperintensity; white matter hyperintensity

White matter hyperintensity (WMH) is a brain lesion detected as a high‐intensity area in magnetic resonance imaging T2 and fluid‐attenuated inversion recovery images, and it has been suggested that WMH reflects damage to small vessels in periventricular and subcortical areas. Although WMH has been l...