Microsatellite instability in hepatocellular carcinoma in non-cirrhotic liver in patients older than 60 years

• Published in: Hepatology research Vol. 39; no. 3; pp. 266 - 273
• Main Authors: Togni, Roberto, Bagla, Nipin, Muiesan, Paolo, Miquel, Rosa, O'Grady, John, Heaton, Nigel, Knisely, Alex S, Portmann, Bernard, Quaglia, Alberto
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.03.2009
• Subjects: carcinoma; hepatocellular; liver; microsatellite instability

Aim:  Hepatocellular carcinoma (HCC) in otherwise normal liver is rare, its pathogenesis remains obscure and the literature on the subject is scarce. We investigated microsatellite instability (MSI) in eight elderly patients (median age 70.7, range 63–76 years) without a clinical history of liver di...