MR Elastography of the Liver and the Spleen Using a Piezoelectric Driver, Single-Shot Wave-Field Acquisition, and Multifrequency Dual Parameter Reconstruction

• Published in: Magnetic resonance in medicine Vol. 71; no. 1; pp. 267 - 277
• Main Authors: Hirsch, Sebastian, Guo, Jing, Reiter, Rolf, Papazoglou, Sebastian, Kroencke, Thomas, Braun, Juergen, Sack, Ingolf
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.01.2014; Wiley Subscription Services, Inc
• Subjects: 3D multifrequency MRE; Adult; Algorithms; Ascites; complex shear modulus; Elastic Modulus; Elasticity Imaging Techniques - instrumentation; Elasticity Imaging Techniques - methods; Equipment Design; Equipment Failure Analysis; Female; Humans; Hypertension, Portal - physiopathology; Image Enhancement - instrumentation; Image Enhancement - methods; Image Interpretation, Computer-Assisted - instrumentation; Image Interpretation, Computer-Assisted - methods; least-squares inversion; liver; Liver - physiopathology; loss tangent; Male; Micro-Electrical-Mechanical Systems - instrumentation; Middle Aged; piezoelectric driver; portal hypertension; Reproducibility of Results; Sensitivity and Specificity; shear waves; Spleen - physiopathology; Viscosity; complex shear modulus; least-squares inversion; portal hypertension; liver; 3D multifrequency MRE; loss tangent; shear waves; piezoelectric driver

Purpose Viscoelastic properties of the liver are sensitive to fibrosis. This study proposes several modifications to existing magnetic resonance elastography (MRE) techniques to improve the accuracy of abdominal MRE. Methods The proposed method comprises the following steps: (i) wave generation by a...