Hepatitis C virus infection causes hypolipidemia regardless of hepatic damage or nutritional state: An epidemiological survey of a large Japanese cohort

• Published in: Hepatology research Vol. 41; no. 6; pp. 530 - 541
• Main Authors: Miyazaki, Teruo, Honda, Akira, Ikegami, Tadashi, Saitoh, Yoshifumi, Hirayama, Takeshi, Hara, Takashi, Doy, Mikio, Matsuzaki, Yasushi
• Format: Journal Article
• Language: English
• Published: Melbourne, Australia Blackwell Publishing Asia 01.06.2011
• Subjects: health examination; high-density lipoprotein cholesterol; low-density lipoprotein cholesterol; total cholesterol; triglyceride

Aim:  Infection with hepatitis C virus (HCV) is the leading cause of liver cirrhosis that develops into hepatocellular carcinoma. Previous studies have shown in vitro that lipids within hepatocytes are crucially important for a series of HCV infection–proliferation–release processes. On the other ha...