Oral tolerance

Multiple mechanisms of tolerance are induced by oral antigen. Low doses favor active suppression, whereas higher doses favor clonal anergy/deletion. Oral antigen induces T‐helper 2 [interleukin (IL)‐4/IL‐10] and Th3 [transforming growth factor (TGF)‐β] T cells plus CD4+CD25+ regulatory cells and lat...

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Bibliographic Details
Published inImmunological reviews Vol. 206; no. 1; pp. 232 - 259
Main Authors Faria, Ana M. C., Weiner, Howard L.
Format Journal Article
LanguageEnglish
Published Oxford, UK; Malden, USA Munksgaard International Publishers 01.08.2005
Subjects
Animals
Antigens - administration & dosage
Antigens - immunology
Humans
Immune Tolerance
Immunity, Mucosal
Intestinal Mucosa - immunology
Mouth Mucosa - immunology
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