Two consecutive deep sinus tract cultures predict the pathogen of osteomyelitis
Abstract Objectives The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula. Methods This was a non-ran...
Saved in:
Published in | International journal of infectious diseases Vol. 14; no. 5; pp. e390 - e393 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Canada
Elsevier Ltd
01.05.2010
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Abstract Objectives The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula. Methods This was a non-randomized, prospective diagnostic trial at the Orthopedic Service of the University Hospital of Geneva. Each patient with osteomyelitis with a cutaneous sinus tract had four microbiological samples taken: two consecutive sinus tract cultures with bone contact at different times (samples A-1 and A-2), surgical bone biopsy performed through the sinus tract (sample B), and a surgical bone biopsy performed through an uninfected area outside the sinus tract (sample C), the latter considered as the ‘gold standard’. Results One hundred and forty-one patients with 154 episodes of osteomyelitis were included in the study. When both sinus tract cultures yielded the same microorganism (86.4%), the concordance between both samples A and sample C was 96%. In the case of identical sinus tract culture infections, sensitivity was 91%, specificity 86%, and accuracy 90%. The accuracy in monomicrobial infections (50%) was higher than in polymicrobial infections (94.3% vs. 78.9%, respectively; p = 0.02). Conclusions In cases of monomicrobial osteomyelitis with sinus tract, two concordant tract cultures with bone contact accurately predict the pathogen. |
---|---|
AbstractList | The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula.
This was a non-randomized, prospective diagnostic trial at the Orthopedic Service of the University Hospital of Geneva. Each patient with osteomyelitis with a cutaneous sinus tract had four microbiological samples taken: two consecutive sinus tract cultures with bone contact at different times (samples A-1 and A-2), surgical bone biopsy performed through the sinus tract (sample B), and a surgical bone biopsy performed through an uninfected area outside the sinus tract (sample C), the latter considered as the ‘gold standard’.
One hundred and forty-one patients with 154 episodes of osteomyelitis were included in the study. When both sinus tract cultures yielded the same microorganism (86.4%), the concordance between both samples A and sample C was 96%. In the case of identical sinus tract culture infections, sensitivity was 91%, specificity 86%, and accuracy 90%. The accuracy in monomicrobial infections (50%) was higher than in polymicrobial infections (94.3% vs. 78.9%, respectively;
p
=
0.02).
In cases of monomicrobial osteomyelitis with sinus tract, two concordant tract cultures with bone contact accurately predict the pathogen. The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula. This was a non-randomized, prospective diagnostic trial at the Orthopedic Service of the University Hospital of Geneva. Each patient with osteomyelitis with a cutaneous sinus tract had four microbiological samples taken: two consecutive sinus tract cultures with bone contact at different times (samples A-1 and A-2), surgical bone biopsy performed through the sinus tract (sample B), and a surgical bone biopsy performed through an uninfected area outside the sinus tract (sample C), the latter considered as the 'gold standard'. One hundred and forty-one patients with 154 episodes of osteomyelitis were included in the study. When both sinus tract cultures yielded the same microorganism (86.4%), the concordance between both samples A and sample C was 96%. In the case of identical sinus tract culture infections, sensitivity was 91%, specificity 86%, and accuracy 90%. The accuracy in monomicrobial infections (50%) was higher than in polymicrobial infections (94.3% vs. 78.9%, respectively; p=0.02). In cases of monomicrobial osteomyelitis with sinus tract, two concordant tract cultures with bone contact accurately predict the pathogen. OBJECTIVESThe value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula.METHODSThis was a non-randomized, prospective diagnostic trial at the Orthopedic Service of the University Hospital of Geneva. Each patient with osteomyelitis with a cutaneous sinus tract had four microbiological samples taken: two consecutive sinus tract cultures with bone contact at different times (samples A-1 and A-2), surgical bone biopsy performed through the sinus tract (sample B), and a surgical bone biopsy performed through an uninfected area outside the sinus tract (sample C), the latter considered as the 'gold standard'.RESULTSOne hundred and forty-one patients with 154 episodes of osteomyelitis were included in the study. When both sinus tract cultures yielded the same microorganism (86.4%), the concordance between both samples A and sample C was 96%. In the case of identical sinus tract culture infections, sensitivity was 91%, specificity 86%, and accuracy 90%. The accuracy in monomicrobial infections (50%) was higher than in polymicrobial infections (94.3% vs. 78.9%, respectively; p=0.02).CONCLUSIONSIn cases of monomicrobial osteomyelitis with sinus tract, two concordant tract cultures with bone contact accurately predict the pathogen. Abstract Objectives The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between deep sinus tract cultures and bone cultures in cases of osteomyelitis with a cutaneous fistula. Methods This was a non-randomized, prospective diagnostic trial at the Orthopedic Service of the University Hospital of Geneva. Each patient with osteomyelitis with a cutaneous sinus tract had four microbiological samples taken: two consecutive sinus tract cultures with bone contact at different times (samples A-1 and A-2), surgical bone biopsy performed through the sinus tract (sample B), and a surgical bone biopsy performed through an uninfected area outside the sinus tract (sample C), the latter considered as the ‘gold standard’. Results One hundred and forty-one patients with 154 episodes of osteomyelitis were included in the study. When both sinus tract cultures yielded the same microorganism (86.4%), the concordance between both samples A and sample C was 96%. In the case of identical sinus tract culture infections, sensitivity was 91%, specificity 86%, and accuracy 90%. The accuracy in monomicrobial infections (50%) was higher than in polymicrobial infections (94.3% vs. 78.9%, respectively; p = 0.02). Conclusions In cases of monomicrobial osteomyelitis with sinus tract, two concordant tract cultures with bone contact accurately predict the pathogen. |
Author | Vuagnat, Albert Hoffmeyer, Pierre Bernard, Louis Rohner, Peter Uçkay, Ilker Assal, Mathieu Stern, Richard |
Author_xml | – sequence: 1 fullname: Bernard, Louis – sequence: 2 fullname: Uçkay, Ilker – sequence: 3 fullname: Vuagnat, Albert – sequence: 4 fullname: Assal, Mathieu – sequence: 5 fullname: Stern, Richard – sequence: 6 fullname: Rohner, Peter – sequence: 7 fullname: Hoffmeyer, Pierre |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19736030$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kc2L1TAUxYOMOB_6D7iQ7ly13nw0aUAEGXRGGJiFI7gLaXqfk9qX1CQdef-9Le-B4MLVvVzOOXB_55KchRiQkNcUGgpUvhsbP_qhYQC6AdkA1c_IBe1UV_OW0rN1Z0BrrSg7J5c5jwAgpOxekHOqFZfA4YLcP_yOlYsho1uKf8JqQJyr7MOSq5KsK5VbprIkzNWccPDroTxiNdvyGH9gqOKuirlg3B9w8sXnl-T5zk4ZX53mFfn2-dPD9W19d3_z5frjXe1aJkqNsuPKtq7not0JoQWzQre0V8i4GCR2_aAtBak17zpFZa8dt4MSgI63gIpfkbfH3DnFXwvmYvY-O5wmGzAu2SgugImuk6uSHZUuxZwT7syc_N6mg6FgNo5mNBtHs3E0IM3KcTW9OcUv_R6Hv5YTuFXw_ijA9cknj8lk5zG4FVFCV8wQ_f_zP_xjd5MP3tnpJx4wj3FJYcVnqMnMgPm6NbkVCRqAKfWd_wHe85rF |
CitedBy_id | crossref_primary_10_1016_j_medmal_2019_10_012 crossref_primary_10_1007_s10096_010_1078_9 crossref_primary_10_1053_j_jfas_2018_12_010 crossref_primary_10_1148_radiol_231348 crossref_primary_10_1302_2058_5241_6_210011 crossref_primary_10_1016_j_jiph_2020_08_010 crossref_primary_10_1016_j_diabres_2017_06_006 crossref_primary_10_1053_j_jfas_2018_05_010 crossref_primary_10_1007_s11908_012_0286_0 crossref_primary_10_1002_dmrr_2425 crossref_primary_10_1080_14787210_2018_1417037 crossref_primary_10_1093_cid_cis346 crossref_primary_10_1177_1534734614550311 crossref_primary_10_1007_s00259_019_4262_x crossref_primary_10_1016_j_jcot_2016_05_007 crossref_primary_10_3390_antibiotics12010013 crossref_primary_10_1053_j_jfas_2011_08_005 crossref_primary_10_1586_eri_10_122 crossref_primary_10_1007_s00330_019_06326_1 |
Cites_doi | 10.1086/498112 10.7547/87507315-85-10-533 10.1128/AAC.01435-06 10.1111/j.1464-5491.2005.01764.x 10.1302/0301-620X.79B4.7316 10.1001/jama.239.26.2772 10.1258/004947506775599003 10.1046/j.1464-5491.2001.00584.x 10.1186/1471-2334-2-8 10.2106/00004623-199405000-00006 10.1016/S0140-6736(04)16727-5 10.2106/00004623-199173050-00014 10.1086/424846 10.1097/00000441-200106000-00002 |
ContentType | Journal Article |
Copyright | International Society for Infectious Diseases 2009 International Society for Infectious Diseases Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. |
Copyright_xml | – notice: International Society for Infectious Diseases – notice: 2009 International Society for Infectious Diseases – notice: Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. |
DBID | 6I. AAFTH CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/j.ijid.2009.06.019 |
DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Public Health |
EISSN | 1878-3511 |
EndPage | e393 |
ExternalDocumentID | 10_1016_j_ijid_2009_06_019 19736030 S120197120900277X 1_s2_0_S120197120900277X |
Genre | Clinical Trial Journal Article |
GroupedDBID | --- --K .1- .FO .~1 0R~ 0SF 1B1 1P~ 1~. 1~5 29J 3O- 3V. 4.4 457 4G. 53G 5GY 5VS 6I. 7-5 71M 7X7 88E 8C1 8FI 8FJ 8FQ 8R4 8R5 AACTN AAEDW AAFTH AAIKJ AALRI AAQFI AAQXK AARKO AAXUO ABBQC ABFRF ABMAC ABUWG ABVKL ACGFO ADBBV ADEZE ADMUD ADVLN AEFWE AEKER AENEX AEVXI AEXQZ AFCTW AFJKZ AFKRA AFRHN AFTJW AGEKW AGHFR AGYEJ AHMBA AITUG AJRQY AJUYK AKRWK ALIPV ALMA_UNASSIGNED_HOLDINGS AMRAJ ASPBG AVWKF AZFZN BAWUL BCNDV BENPR BPHCQ BR6 BVXVI CCPQU CS3 DIK DU5 DWQXO E3Z EBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FNPLU FYUFA G-Q GBLVA GROUPED_DOAJ GX1 HMCUK HVGLF HZ~ IHE IXB J1W KQ8 M1P M3C M3G M41 MO0 N9A NCXOZ O-L O9- OD- OK1 OO. OZT P-8 P-9 P2P PC. PQQKQ PROAC PSQYO Q2X Q38 QTD R2- RIG ROL RPZ RWL RXW SDF SDG SEL SES SEW SSZ TAE UKHRP UNMZH Z5R CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c524t-e6837a5cb345f44942a4951b7e234d6e8bd9a10699388716b9c3ad740ec350e73 |
IEDL.DBID | ABVKL |
ISSN | 1201-9712 |
IngestDate | Fri Aug 16 10:22:12 EDT 2024 Thu Sep 26 15:55:56 EDT 2024 Sat Sep 28 07:48:06 EDT 2024 Fri Feb 23 02:29:00 EST 2024 Tue Oct 15 22:56:13 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 5 |
Keywords | Osteomyelitis Predilection Sinus tract Pathogen Culture |
Language | English |
License | http://www.elsevier.com/open-access/userlicense/1.0 Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c524t-e6837a5cb345f44942a4951b7e234d6e8bd9a10699388716b9c3ad740ec350e73 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
OpenAccessLink | https://www.sciencedirect.com/science/article/pii/S120197120900277X |
PMID | 19736030 |
PQID | 734024886 |
PQPubID | 23479 |
ParticipantIDs | proquest_miscellaneous_734024886 crossref_primary_10_1016_j_ijid_2009_06_019 pubmed_primary_19736030 elsevier_sciencedirect_doi_10_1016_j_ijid_2009_06_019 elsevier_clinicalkeyesjournals_1_s2_0_S120197120900277X |
PublicationCentury | 2000 |
PublicationDate | 2010-05-01 |
PublicationDateYYYYMMDD | 2010-05-01 |
PublicationDate_xml | – month: 05 year: 2010 text: 2010-05-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | Canada |
PublicationPlace_xml | – name: Canada |
PublicationTitle | International journal of infectious diseases |
PublicationTitleAlternate | Int J Infect Dis |
PublicationYear | 2010 |
Publisher | Elsevier Ltd |
Publisher_xml | – name: Elsevier Ltd |
References | Kessler, Piemont, Ortega, Lesens, Boeri, Averous (bib5) 2006; 23 Pellizzer, Strazzabosco, Presi, Furlan, Lora, Benedetti (bib6) 2001; 18 Onuminya (bib15) 2006; 36 Lew, Waldvogel (bib1) 2004; 364 Perry, Pearson, Miller (bib8) 1991; 73 Agarwal, Zahid, Sherwani, Abbas, Huda, Khan (bib13) 2005; 71 Snydman, Jacobus, McDermott, Ruthazer, Golan, Goldstein (bib18) 2007; 51 Jacobson, Sieling (bib3) 1987; 72 Lipsky, Berendt, Deery, Embil, Joseph, Karchmer (bib11) 2004; 39 Khatri, Wagner, Sohnle (bib4) 2001; 321 Patzakis, Wilkins, Kumar, Holtom, Greenbaum, Ressler (bib14) 1994; 76 Helbling, Zellweger, Altpeter, Boubaker (bib10) 2006; 2 Mousa (bib16) 1997; 79 Zuluaga, Galvis, Jaimes, Vesga (bib12) 2002; 2 National Committee for Clinical and Laboratory Standards., Performance standards for antimicrobial susceptibility testing. Informational supplement M100-S9. Wayne, PA: NCCLS; 1999. Mackowiak, Jones, Smith (bib2) 1978; 239 Senneville, Melliez, Beltrand, Legout, Valette, Cazaubiel (bib7) 2006; 42 Armstrong, Liswood, Todd (bib17) 1995; 85 Helbling (10.1016/j.ijid.2009.06.019_bib10) 2006; 2 Mousa (10.1016/j.ijid.2009.06.019_bib16) 1997; 79 Perry (10.1016/j.ijid.2009.06.019_bib8) 1991; 73 Pellizzer (10.1016/j.ijid.2009.06.019_bib6) 2001; 18 Lipsky (10.1016/j.ijid.2009.06.019_bib11) 2004; 39 Onuminya (10.1016/j.ijid.2009.06.019_bib15) 2006; 36 Snydman (10.1016/j.ijid.2009.06.019_bib18) 2007; 51 Patzakis (10.1016/j.ijid.2009.06.019_bib14) 1994; 76 10.1016/j.ijid.2009.06.019_bib9 Armstrong (10.1016/j.ijid.2009.06.019_bib17) 1995; 85 Kessler (10.1016/j.ijid.2009.06.019_bib5) 2006; 23 Senneville (10.1016/j.ijid.2009.06.019_bib7) 2006; 42 Agarwal (10.1016/j.ijid.2009.06.019_bib13) 2005; 71 Khatri (10.1016/j.ijid.2009.06.019_bib4) 2001; 321 Lew (10.1016/j.ijid.2009.06.019_bib1) 2004; 364 Mackowiak (10.1016/j.ijid.2009.06.019_bib2) 1978; 239 Jacobson (10.1016/j.ijid.2009.06.019_bib3) 1987; 72 Zuluaga (10.1016/j.ijid.2009.06.019_bib12) 2002; 2 |
References_xml | – volume: 72 start-page: 476 year: 1987 end-page: 477 ident: bib3 article-title: Microbiology of secondary osteomyelitis. Value of bone biopsy publication-title: S Afr Med J contributor: fullname: Sieling – volume: 51 start-page: 1649 year: 2007 end-page: 1655 ident: bib18 article-title: National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004 publication-title: Antimicrob Agents Chemother contributor: fullname: Goldstein – volume: 42 start-page: 57 year: 2006 end-page: 62 ident: bib7 article-title: Culture of percutaneous bone biopsy specimens for diagnosis of diabetic foot osteomyelitis: concordance with ulcer swab cultures publication-title: Clin Infect Dis contributor: fullname: Cazaubiel – volume: 73 start-page: 745 year: 1991 end-page: 749 ident: bib8 article-title: Accuracy of cultures of material from swabbing of the superficial aspect of the wound and needle biopsy in the preoperative assessment of osteomyelitis publication-title: J Bone Joint Surg Am contributor: fullname: Miller – volume: 239 start-page: 2772 year: 1978 end-page: 2775 ident: bib2 article-title: Diagnostic value of sinus-tract cultures in chronic osteomyelitis publication-title: JAMA contributor: fullname: Smith – volume: 39 start-page: 885 year: 2004 end-page: 910 ident: bib11 article-title: Diagnosis and treatment of diabetic foot infections publication-title: Clin Infect Dis contributor: fullname: Karchmer – volume: 76 start-page: 664 year: 1994 end-page: 666 ident: bib14 article-title: Comparison of the results of bacterial cultures from multiple sites in chronic osteomyelitis of long bones. A prospective study publication-title: J Bone Joint Surg Am contributor: fullname: Ressler – volume: 364 start-page: 369 year: 2004 end-page: 379 ident: bib1 article-title: Osteomyelitis publication-title: Lancet contributor: fullname: Waldvogel – volume: 79 start-page: 567 year: 1997 end-page: 569 ident: bib16 article-title: Evaluation of sinus-tract cultures in chronic bone infection publication-title: J Bone Joint Surg Br contributor: fullname: Mousa – volume: 18 start-page: 822 year: 2001 end-page: 827 ident: bib6 article-title: Deep tissue biopsy vs. superficial swab culture monitoring in the microbiological assessment of limb-threatening diabetic foot infection publication-title: Diabet Med contributor: fullname: Benedetti – volume: 36 start-page: 38 year: 2006 end-page: 39 ident: bib15 article-title: A prospective evaluation of the diagnostic value of sinus specimen cultures in chronic osteomyelitis publication-title: Trop Doct contributor: fullname: Onuminya – volume: 71 start-page: 209 year: 2005 end-page: 212 ident: bib13 article-title: Comparison of the results of sinus tract culture and sequestrum culture in chronic osteomyelitis publication-title: Acta Orthop Belg contributor: fullname: Khan – volume: 85 start-page: 533 year: 1995 end-page: 537 ident: bib17 article-title: Prevalence of mixed infections in the diabetic pedal wound. A retrospective review of 112 infections publication-title: J Am Pediatr Med Assoc contributor: fullname: Todd – volume: 2 start-page: 8 year: 2002 end-page: 16 ident: bib12 article-title: Lack of microbiological concordance between bone and non-bone specimens in chronic osteomyelitis: an observational study publication-title: BMC Infect Dis contributor: fullname: Vesga – volume: 321 start-page: 367 year: 2001 end-page: 371 ident: bib4 article-title: Effect of bone biopsy in guiding antimicrobial therapy for osteomyelitis complicating open wounds publication-title: Am J Med Sci contributor: fullname: Sohnle – volume: 2 start-page: 2276 year: 2006 end-page: 2278 ident: bib10 article-title: Epidemiology and treatment of tuberculosis in Switzerland publication-title: Rev Med Suisse contributor: fullname: Boubaker – volume: 23 start-page: 99 year: 2006 end-page: 102 ident: bib5 article-title: Comparison of microbiological results of needle puncture vs. superficial swab in infected diabetic foot ulcer with osteomyelitis publication-title: Diabet Med contributor: fullname: Averous – volume: 42 start-page: 57 year: 2006 ident: 10.1016/j.ijid.2009.06.019_bib7 article-title: Culture of percutaneous bone biopsy specimens for diagnosis of diabetic foot osteomyelitis: concordance with ulcer swab cultures publication-title: Clin Infect Dis doi: 10.1086/498112 contributor: fullname: Senneville – volume: 85 start-page: 533 year: 1995 ident: 10.1016/j.ijid.2009.06.019_bib17 article-title: Prevalence of mixed infections in the diabetic pedal wound. A retrospective review of 112 infections publication-title: J Am Pediatr Med Assoc doi: 10.7547/87507315-85-10-533 contributor: fullname: Armstrong – volume: 51 start-page: 1649 year: 2007 ident: 10.1016/j.ijid.2009.06.019_bib18 article-title: National survey on the susceptibility of Bacteroides fragilis group: report and analysis of trends in the United States from 1997 to 2004 publication-title: Antimicrob Agents Chemother doi: 10.1128/AAC.01435-06 contributor: fullname: Snydman – volume: 23 start-page: 99 year: 2006 ident: 10.1016/j.ijid.2009.06.019_bib5 article-title: Comparison of microbiological results of needle puncture vs. superficial swab in infected diabetic foot ulcer with osteomyelitis publication-title: Diabet Med doi: 10.1111/j.1464-5491.2005.01764.x contributor: fullname: Kessler – volume: 79 start-page: 567 year: 1997 ident: 10.1016/j.ijid.2009.06.019_bib16 article-title: Evaluation of sinus-tract cultures in chronic bone infection publication-title: J Bone Joint Surg Br doi: 10.1302/0301-620X.79B4.7316 contributor: fullname: Mousa – ident: 10.1016/j.ijid.2009.06.019_bib9 – volume: 239 start-page: 2772 year: 1978 ident: 10.1016/j.ijid.2009.06.019_bib2 article-title: Diagnostic value of sinus-tract cultures in chronic osteomyelitis publication-title: JAMA doi: 10.1001/jama.239.26.2772 contributor: fullname: Mackowiak – volume: 36 start-page: 38 year: 2006 ident: 10.1016/j.ijid.2009.06.019_bib15 article-title: A prospective evaluation of the diagnostic value of sinus specimen cultures in chronic osteomyelitis publication-title: Trop Doct doi: 10.1258/004947506775599003 contributor: fullname: Onuminya – volume: 18 start-page: 822 year: 2001 ident: 10.1016/j.ijid.2009.06.019_bib6 article-title: Deep tissue biopsy vs. superficial swab culture monitoring in the microbiological assessment of limb-threatening diabetic foot infection publication-title: Diabet Med doi: 10.1046/j.1464-5491.2001.00584.x contributor: fullname: Pellizzer – volume: 71 start-page: 209 year: 2005 ident: 10.1016/j.ijid.2009.06.019_bib13 article-title: Comparison of the results of sinus tract culture and sequestrum culture in chronic osteomyelitis publication-title: Acta Orthop Belg contributor: fullname: Agarwal – volume: 72 start-page: 476 year: 1987 ident: 10.1016/j.ijid.2009.06.019_bib3 article-title: Microbiology of secondary osteomyelitis. Value of bone biopsy publication-title: S Afr Med J contributor: fullname: Jacobson – volume: 2 start-page: 2276 year: 2006 ident: 10.1016/j.ijid.2009.06.019_bib10 article-title: Epidemiology and treatment of tuberculosis in Switzerland publication-title: Rev Med Suisse contributor: fullname: Helbling – volume: 2 start-page: 8 year: 2002 ident: 10.1016/j.ijid.2009.06.019_bib12 article-title: Lack of microbiological concordance between bone and non-bone specimens in chronic osteomyelitis: an observational study publication-title: BMC Infect Dis doi: 10.1186/1471-2334-2-8 contributor: fullname: Zuluaga – volume: 76 start-page: 664 year: 1994 ident: 10.1016/j.ijid.2009.06.019_bib14 article-title: Comparison of the results of bacterial cultures from multiple sites in chronic osteomyelitis of long bones. A prospective study publication-title: J Bone Joint Surg Am doi: 10.2106/00004623-199405000-00006 contributor: fullname: Patzakis – volume: 364 start-page: 369 year: 2004 ident: 10.1016/j.ijid.2009.06.019_bib1 article-title: Osteomyelitis publication-title: Lancet doi: 10.1016/S0140-6736(04)16727-5 contributor: fullname: Lew – volume: 73 start-page: 745 year: 1991 ident: 10.1016/j.ijid.2009.06.019_bib8 article-title: Accuracy of cultures of material from swabbing of the superficial aspect of the wound and needle biopsy in the preoperative assessment of osteomyelitis publication-title: J Bone Joint Surg Am doi: 10.2106/00004623-199173050-00014 contributor: fullname: Perry – volume: 39 start-page: 885 year: 2004 ident: 10.1016/j.ijid.2009.06.019_bib11 article-title: Diagnosis and treatment of diabetic foot infections publication-title: Clin Infect Dis doi: 10.1086/424846 contributor: fullname: Lipsky – volume: 321 start-page: 367 year: 2001 ident: 10.1016/j.ijid.2009.06.019_bib4 article-title: Effect of bone biopsy in guiding antimicrobial therapy for osteomyelitis complicating open wounds publication-title: Am J Med Sci doi: 10.1097/00000441-200106000-00002 contributor: fullname: Khatri |
SSID | ssj0004668 |
Score | 2.0728607 |
Snippet | Abstract Objectives The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the... The value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance between... OBJECTIVESThe value of non-bone microbiological cultures in the diagnosis of osteomyelitis with sinus tract is not clear. We aimed to establish the concordance... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | e390 |
SubjectTerms | Adult Aged Aged, 80 and over Bacteria - isolation & purification Bone and Bones - microbiology Bone and Bones - pathology Cell Culture Techniques Culture Cutaneous Fistula - microbiology Cutaneous Fistula - pathology Female Humans Infectious Disease Male Middle Aged Osteomyelitis Osteomyelitis - diagnosis Osteomyelitis - microbiology Osteomyelitis - pathology Paranasal Sinuses - microbiology Pathogen Predilection Prospective Studies Pulmonary/Respiratory Reproducibility of Results Sensitivity and Specificity Sinus tract Young Adult |
Title | Two consecutive deep sinus tract cultures predict the pathogen of osteomyelitis |
URI | https://www.clinicalkey.es/playcontent/1-s2.0-S120197120900277X https://dx.doi.org/10.1016/j.ijid.2009.06.019 https://www.ncbi.nlm.nih.gov/pubmed/19736030 https://search.proquest.com/docview/734024886 |
Volume | 14 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Jb9QwFH5qpxJCQggKtANl5AM3lE4cb8mxrVoVyiJEi-ZmxfGLlEpNRk1GiAu_HTt2WMRy4OJDFMfxs_0W-_ueAV4wVipZ1FVijTEJr3ORlCJPXcFKirVAake0xTt5fsVfr8RqC04mLoyHVUbdH3T6qK3jk2WU5nLdNMuP1NmuQnnup4-t1GobdjJ_zDSDnaPjTxdvfqJHBkacez_xFSJ3JsC8muvGxrSV8nBMuPNn-_Q3_3O0Q2cP4H50IMlR-MeHsIXtLtx5G4_Id-Fe2IgjgV_0CN5ffu5I5THT1carNmIR16Rv2k1PBk-RIiH5BvZkfeu_MhDnExJ_U3HnJhfpauJ5IN3NF_RIuf4xXJ2dXp6cJ_EWhaQSGR8SlC4GLUVlGBc15wXPShcUUaMwY9xKzI0tShcYOkcl99GTKSpWWsVTrJhIUbEnMGu7FveBMCMNZsKkiIZTrHJuTU3zlFmZIdZyDi8n2el1SJahJxTZtfaS9rdeFtpD6WgxBzWJV080UKe4sI-rqNdU95lO9W8jPQfxveYvk0U7O_DPFsk0itqtIn80UrbYbXqtGPfJ3XLXhb0wuj86UCgmnSp8-p-NPoO7E-IgpQcwG243-Nw5MoNZwPbhV7qI03Uxbge48tXq2JUXH_Jvynf0mA |
link.rule.ids | 315,786,790,870,3525,4521,27600,27955,27956,45618,45696,45907 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VIgESQlAeXZ4-cENh4_iVHKGiWqAtB7bS3qw4mUipRLJqsqr493hih4d4HLjkEDlxPGPPI_6-McBLIUqji6ZKaudcIptcJaXKU38RJcdGIa8ntMWZXp3LDxu12YOjmQtDsMpo-4NNn6x1vLOM0lxu23b5mXvfVRjiflJuZTbX4LpUPtcjFt_m7U_kyMCH860Tah6ZMwHk1V60dSxaqV9P5Xb-7J3-Fn1OXuj4LtyJ4SN7E77wHuxhdwA3TuMG-QHcDr_hWGAX3YdP66ueVYSYrnZk2FiNuGVD2-0GNhJBioXSGziw7SW9ZWQ-ImR0TnHvpxbrG0YskP7LVySc3PAAzo_frY9WSTxDIalUJscEtc9AS1U5IVUjZSGz0qdE3BnMhKw15q4uSp8W-jAlp9zJFZUoayNTrIRK0YiHsN_1HR4CE047zJRLEZ3kWOWydg3PU1HrDLHRC3g1y85uQ6kMO2PILixJms68LCwB6XixADOL184kUG-2cIhraLDcDplN7W96XoD6_uQvU8V6L_DPHtmsRevXEG2MlB32u8EaIam0W-6H8Cho98cACiO0N4SP_7PTF3BztT49sSfvzz4-gVsz9iDlT2F_vNzhMx_SjO75NGW_AdwV8oI |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Two+consecutive+deep+sinus+tract+cultures+predict+the+pathogen+of+osteomyelitis&rft.jtitle=International+journal+of+infectious+diseases&rft.au=Bernard%2C+Louis&rft.au=U%C3%A7kay%2C+Ilker&rft.au=Vuagnat%2C+Albert&rft.au=Assal%2C+Mathieu&rft.date=2010-05-01&rft.eissn=1878-3511&rft.volume=14&rft.issue=5&rft.spage=e390&rft.epage=e393&rft_id=info:doi/10.1016%2Fj.ijid.2009.06.019&rft.externalDBID=NO_FULL_TEXT |
thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F12019712%2FS1201971210X00066%2Fcov150h.gif |