Fragile X Mental Retardation Protein and Cerebral Expression of Metabotropic Glutamate Receptor Subtype 5 in Men with Fragile X Syndrome: A Pilot Study - Brašić, James Robert; Goodman, Jack Alexander; Nandi, Ayon; Russell, David S.; Jennings, Danna; Barret, Olivier; Martin, Samuel D.; Slifer, Keith; Sedlak, Thomas; Mathur, Anil Kumar; Seibyl, John P.; Berry-Kravis, Elizabeth M.; et al. (Brain sciences, 2022)
Keywords: Alzheimer's disease; Animal models; anterior cingulate cortex; Autism; Benzonitrile; Clinical trials; correlation coefficient; Cortex (cingulate); FMR1 protein; fragile X mental retardation 1 gene (FMR1); Fragile X syndrome; Genotype & phenotype; Glutamatergic transmission; Glutamic acid receptors (metabotropic); Intellectual disabilities; Kinases; Life Sciences; linear regression; Mosaicism; Neurodegenerative diseases; neurodevelopmental disorders; neuroimaging; Occipital lobe; Phenotypes; Positron emission tomography; Precision medicine; Protein synthesis; Proteins; Thalamus; Tomography; radiotracer; positron emission tomography (PET); linear regression; fragile X mental retardation 1 gene (FMR1); correlation coefficient; neurodevelopmental disorders; temporal cortex; anterior cingulate cortex; neuroimaging; thalamus