Variable Dendritic Integration in Hippocampal CA3 Pyramidal Neurons
The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons....
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Published in | Neuron (Cambridge, Mass.) Vol. 80; no. 6; pp. 1438 - 1450 |
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Main Authors | , |
Format | Journal Article |
Language | English |
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18.12.2013
Elsevier Limited Cell Press |
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Abstract | The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We found that thin dendrites of CA3 pyramidal neurons integrate synchronous synaptic input in a highly supralinear fashion. The amplification was primarily mediated by NMDA receptor activation and was present over a relatively broad range of spatiotemporal input patterns. The decay of voltage responses, temporal summation, and action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activated inwardly rectifying K+ current. Our results suggest that plastic dendritic integrative mechanisms may support ensemble behavior in pyramidal neurons of the hippocampal circuitry.
•Active nonlinear dendritic integration in CA3 pyramidal neurons•NMDARs mediate amplification of synchronous synaptic inputs•Compartmentalized control of dendritic integration and somatic output by K+ channels
Makara and Magee demonstrate NMDA receptor-mediated supralinear dendritic integration of multiple coactive synaptic inputs in thin dendrites of hippocampal CA3 pyramidal neurons and reveal a powerful regulation of these NMDA spikes by G-protein-activated inwardly rectifying K+ channels. |
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AbstractList | The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We found that thin dendrites of CA3 pyramidal neurons integrate synchronous synaptic input in a highly supralinear fashion. The amplification was primarily mediated by NMDA receptor activation and was present over a relatively broad range of spatiotemporal input patterns. The decay of voltage responses, temporal summation, and action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activated inwardly rectifying K
+
current. Our results suggest that plastic dendritic integrative mechanisms may support ensemble behavior in pyramidal neurons of the hippocampal circuitry.
•
Active nonlinear dendritic integration in CA3 pyramidal neurons
•
NMDARs mediate amplification of synchronous synaptic inputs
•
Compartmentalized control of dendritic integration and somatic output by K+ channels
Makara and Magee demonstrate NMDA receptor-mediated supralinear dendritic integration of multiple coactive synaptic inputs in thin dendrites of hippocampal CA3 pyramidal neurons and reveal a powerful regulation of these NMDA spikes by G-protein-activated inwardly rectifying K+ channels. The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We found that thin dendrites of CA3 pyramidal neurons integrate synchronous synaptic input in a highly supralinear fashion. The amplification was primarily mediated by NMDA receptor activation and was present over a relatively broad range of spatiotemporal input patterns. The decay of voltage responses, temporal summation, and action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activated inwardly rectifying K+ current. Our results suggest that plastic dendritic integrative mechanisms may support ensemble behavior in pyramidal neurons of the hippocampal circuitry. The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We found that thin dendrites of CA3 pyramidal neurons integrate synchronous synaptic input in a highly supralinear fashion. The amplification was primarily mediated by NMDA receptor activation and was present over a relatively broad range of spatiotemporal input patterns. The decay of voltage responses, temporal summation, and action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activated inwardly rectifying K+ current. Our results suggest that plastic dendritic integrative mechanisms may support ensemble behavior in pyramidal neurons of the hippocampal circuitry. •Active nonlinear dendritic integration in CA3 pyramidal neurons•NMDARs mediate amplification of synchronous synaptic inputs•Compartmentalized control of dendritic integration and somatic output by K+ channels Makara and Magee demonstrate NMDA receptor-mediated supralinear dendritic integration of multiple coactive synaptic inputs in thin dendrites of hippocampal CA3 pyramidal neurons and reveal a powerful regulation of these NMDA spikes by G-protein-activated inwardly rectifying K+ channels. The hippocampal CA3 region is essential for pattern completion and generation of sharp-wave ripples. During these operations, coordinated activation of ensembles of CA3 pyramidal neurons produces spatiotemporally structured input patterns arriving onto dendrites of recurrently connected CA3 neurons. To understand how such input patterns are translated into specific output patterns, we characterized dendritic integration in CA3 pyramidal cells using two-photon imaging and glutamate uncaging. We found that thin dendrites of CA3 pyramidal neurons integrate synchronous synaptic input in a highly supralinear fashion. The amplification was primarily mediated by NMDA receptor activation and was present over a relatively broad range of spatiotemporal input patterns. The decay of voltage responses, temporal summation, and action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activated inwardly rectifying K(+) current. Our results suggest that plastic dendritic integrative mechanisms may support ensemble behavior in pyramidal neurons of the hippocampal circuitry. |
Author | Makara, Judit K. Magee, Jeffrey C. |
AuthorAffiliation | 2 Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA 20147, USA 1 Institute of Experimental Medicine, Hungarian Academy of Sciences, 1083 Budapest, Hungary |
AuthorAffiliation_xml | – name: 1 Institute of Experimental Medicine, Hungarian Academy of Sciences, 1083 Budapest, Hungary – name: 2 Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA 20147, USA |
Author_xml | – sequence: 1 givenname: Judit K. surname: Makara fullname: Makara, Judit K. email: makara.judit@koki.mta.hu organization: Institute of Experimental Medicine, Hungarian Academy of Sciences, 1083 Budapest, Hungary – sequence: 2 givenname: Jeffrey C. surname: Magee fullname: Magee, Jeffrey C. organization: Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA 20147, USA |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/24360546$$D View this record in MEDLINE/PubMed |
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Cites_doi | 10.1038/nature02739 10.1126/science.1210362 10.1523/JNEUROSCI.5684-10.2011 10.1126/science.1189664 10.1523/JNEUROSCI.4178-05.2006 10.1016/j.neuron.2012.06.025 10.1016/S0896-6273(00)80381-5 10.1002/hipo.20676 10.1002/neu.20144 10.1073/pnas.82.5.1558 10.1152/physrev.00021.2009 10.1016/j.neuron.2011.05.043 10.1523/JNEUROSCI.5250-08.2009 10.1113/jphysiol.1986.sp016055 10.1523/JNEUROSCI.3484-05.2005 10.1016/0166-2236(87)90011-7 10.1152/jn.00524.2012 10.1523/JNEUROSCI.23-21-07750.2003 10.1101/lm.1433209 10.1038/nn1449 10.1016/j.tins.2010.03.002 10.1038/nn.3060 10.1038/35005094 10.1073/pnas.95.19.11450 10.1111/j.1749-6632.1999.tb11293.x 10.1016/0014-4886(73)90290-2 10.1152/physrev.00016.2007 10.1038/nn1178 10.1098/rstb.1971.0078 10.1523/JNEUROSCI.1854-12.2013 10.1016/j.pneurobio.2006.04.005 10.1126/science.1071795 10.1126/science.1217276 10.1016/S0959-4388(00)00217-8 10.1016/j.conb.2005.05.013 10.1016/j.neuron.2010.09.023 10.1523/JNEUROSCI.16-20-06374.1996 10.1016/j.neuron.2006.03.016 10.1016/j.tins.2010.01.006 10.1016/j.neuron.2009.01.032 10.1126/science.1171958 10.1002/hipo.450040319 10.1002/jnr.22444 10.1021/bi991205r 10.1016/j.neuron.2011.10.015 10.1111/j.1469-7793.1999.0385t.x 10.1002/1096-9861(20010205)430:2<264::AID-CNE1030>3.0.CO;2-3 10.1016/S0079-6123(08)61248-0 10.1002/hipo.20103 10.1038/nn.2428 10.1038/nrn2834 10.1002/hipo.22002 10.1523/JNEUROSCI.5312-04.2005 10.1016/j.neuron.2004.11.003 10.1016/0306-4522(89)90424-7 10.1038/nature11451 10.1113/jphysiol.1995.sp020521 10.1002/cne.903390204 10.1523/JNEUROSCI.19-14-05875.1999 10.1038/nature06725 10.1113/jphysiol.2006.121343 |
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References | Chen, Johnston (bib8) 2005; 25 Makara, Losonczy, Wen, Magee (bib35) 2009; 12 Guzowski, Knierim, Moser (bib16) 2004; 44 Breton, Stuart (bib5) 2012; 108 McNaughton, Morris (bib37) 1987; 10 Lüscher, Slesinger (bib32) 2010; 11 Amaral, Witter (bib1) 1989; 31 Marr (bib36) 1971; 262 Fellini, Florian, Courtey, Roullet (bib10) 2009; 16 Gasparini, Losonczy, Chen, Johnston, Magee (bib13) 2007; 580 Sanders, Berends, Major, Goldman, Lisman (bib49) 2013; 33 Koyrakh, Luján, Colón, Karschin, Kurachi, Karschin, Wickman (bib22) 2005; 25 Gulledge, Kampa, Stuart (bib15) 2005; 64 Lee, Yoganarasimha, Rao, Knierim (bib27) 2004; 430 Remy, Csicsvari, Beck (bib47) 2009; 61 Shah, Hammond, Hoffman (bib52) 2010; 33 Kim, Guzman, Hu, Jonas (bib20) 2012; 15 Hibino, Inanobe, Furutani, Murakami, Findlay, Kurachi (bib17) 2010; 90 Schiller, Major, Koester, Schiller (bib51) 2000; 404 Sjöström, Rancz, Roth, Häusser (bib53) 2008; 88 Legenstein, Maass (bib28) 2011; 31 Storm (bib56) 1990; 83 Buckmaster, Amaral (bib6) 2001; 430 Treves, Rolls (bib59) 1994; 4 Losonczy, Makara, Magee (bib31) 2008; 452 Sodickson, Bean (bib54) 1996; 16 Coetzee, Amarillo, Chiu, Chow, Lau, McCormack, Moreno, Nadal, Ozaita, Pountney (bib9) 1999; 868 Kesner, Warthen (bib19) 2010; 20 Spruston, Jonas, Sakmann (bib55) 1995; 482 Losonczy, Magee (bib30) 2006; 50 Müller, Beck, Coulter, Remy (bib40) 2012; 75 Wessel, Kristan, Kleinfeld (bib61) 1999; 19 Mizuseki, Royer, Diba, Buzsáki (bib39) 2012; 22 Polsky, Mel, Schiller (bib45) 2009; 29 Takigawa, Alzheimer (bib58) 1999; 517 Ranck (bib46) 1973; 41 Gähwiler, Brown (bib12) 1985; 82 Lüscher, Jan, Stoffel, Malenka, Nicoll (bib33) 1997; 19 O’Neill, Pleydell-Bouverie, Dupret, Csicsvari (bib43) 2010; 33 Urban, Barrionuevo (bib60) 1998; 95 Frick, Magee, Johnston (bib11) 2004; 7 Ariav, Polsky, Schiller (bib3) 2003; 23 Schiller, Schiller (bib50) 2001; 11 Magee, Johnston (bib34) 2005; 15 Kleindienst, Winnubst, Roth-Alpermann, Bonhoeffer, Lohmann (bib21) 2011; 72 Branco, Clark, Häusser (bib4) 2010; 329 Larkum, Nevian, Sandler, Polsky, Schiller (bib25) 2009; 325 Nakazawa, Quirk, Chitwood, Watanabe, Yeckel, Sun, Kato, Carr, Johnston, Wilson, Tonegawa (bib41) 2002; 297 Miles, Wong (bib38) 1986; 373 Rolls, Kesner (bib48) 2006; 79 Lavzin, Rapoport, Polsky, Garion, Schiller (bib26) 2012; 490 Ngo-Anh, Bloodgood, Lin, Sabatini, Maylie, Adelman (bib42) 2005; 8 Jin, Lu (bib18) 1999; 38 Kulik, Vida, Fukazawa, Guetg, Kasugai, Marker, Rigato, Bettler, Wickman, Frotscher, Shigemoto (bib24) 2006; 26 Takahashi, Kitamura, Matsuo, Mayford, Kano, Matsuki, Ikegaya (bib57) 2012; 335 Li, Somogyi, Ylinen, Buzsáki (bib29) 1994; 339 Antic, Zhou, Moore, Short, Ikonomu (bib2) 2010; 88 Buzsáki (bib7) 2010; 68 Gold, Kesner (bib14) 2005; 15 Krueppel, Remy, Beck (bib23) 2011; 71 Palmer, Schulz, Murphy, Ledergerber, Murayama, Larkum (bib44) 2012; 335 9331358 - Neuron. 1997 Sep;19(3):687-95 21040841 - Neuron. 2010 Nov 4;68(3):362-85 12944503 - J Neurosci. 2003 Aug 27;23(21):7750-8 11135261 - J Comp Neurol. 2001 Feb 5;430(2):264-81 15852011 - Nat Neurosci. 2005 May;8(5):642-9 18368112 - Nature. 2008 Mar 27;452(7186):436-41 19650123 - Hippocampus. 2010 Apr;20(4):550-7 16624949 - J Neurosci. 2006 Apr 19;26(16):4289-97 19776275 - J Neurosci. 2009 Sep 23;29(38):11891-903 22940864 - Nature. 2012 Oct 18;490(7420):397-401 20086079 - Physiol Rev. 2010 Jan;90(1):291-366 10572003 - Biochemistry. 1999 Oct 26;38(43):14286-93 22956789 - J Neurophysiol. 2012 Nov;108(10):2810-8 16339040 - J Neurosci. 2005 Dec 7;25(49):11468-78 10407027 - J Neurosci. 1999 Jul 15;19(14):5875-88 3018233 - J Physiol. 1986 Apr;373:397-418 15922583 - Curr Opin Neurobiol. 2005 Jun;15(3):334-42 21835347 - Neuron. 2011 Aug 11;71(3):512-28 7536248 - J Physiol. 1995 Jan 15;482 ( Pt 2):325-52 22388958 - Nat Neurosci. 2012 Apr;15(4):600-6 7842058 - Hippocampus. 1994 Jun;4(3):374-91 15541306 - Neuron. 2004 Nov 18;44(4):581-4 20363038 - Trends Neurosci. 2010 Jul;33(7):307-16 12040087 - Science. 2002 Jul 12;297(5579):211-8 21795531 - J Neurosci. 2011 Jul 27;31(30):10787-802 20389305 - Nat Rev Neurosci. 2010 May;11(5):301-15 20705816 - Science. 2010 Sep 24;329(5999):1671-5 14730307 - Nat Neurosci. 2004 Feb;7(2):126-35 17272353 - J Physiol. 2007 May 1;580(Pt.3):787-800 9736757 - Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11450-5 16781044 - Prog Neurobiol. 2006 May;79(1):1-48 22267814 - Science. 2012 Jan 20;335(6066):353-6 22367959 - Hippocampus. 2012 Aug;22(8):1659-80 16010664 - Hippocampus. 2005;15(6):808-14 4399412 - Philos Trans R Soc Lond B Biol Sci. 1971 Jul 1;262(841):23-81 10414301 - Ann N Y Acad Sci. 1999 Apr 30;868:233-85 23303922 - J Neurosci. 2013 Jan 9;33(2):424-9 2687721 - Neuroscience. 1989;31(3):571-91 4355646 - Exp Neurol. 1973 Nov;41(2):461-531 15229614 - Nature. 2004 Jul 22;430(6998):456-9 19323999 - Neuron. 2009 Mar 26;61(6):906-16 2983351 - Proc Natl Acad Sci U S A. 1985 Mar;82(5):1558-62 10749211 - Nature. 2000 Mar 16;404(6775):285-9 18391179 - Physiol Rev. 2008 Apr;88(2):769-840 22196336 - Neuron. 2011 Dec 22;72(6):1012-24 8815916 - J Neurosci. 1996 Oct 15;16(20):6374-85 22363012 - Science. 2012 Feb 24;335(6071):989-93 16630839 - Neuron. 2006 Apr 20;50(2):291-307 8300905 - J Comp Neurol. 1994 Jan 8;339(2):181-208 19661433 - Science. 2009 Aug 7;325(5941):756-60 15884003 - J Neurobiol. 2005 Jul;64(1):75-90 2203097 - Prog Brain Res. 1990;83:161-87 10332089 - J Physiol. 1999 Jun 1;517 ( Pt 2):385-90 20207025 - Trends Neurosci. 2010 May;33(5):220-9 22958825 - Neuron. 2012 Sep 6;75(5):851-64 15829630 - J Neurosci. 2005 Apr 13;25(15):3787-92 19470655 - Learn Mem. 2009 Jun;16(6):387-94 19898470 - Nat Neurosci. 2009 Dec;12(12):1485-7 11399433 - Curr Opin Neurobiol. 2001 Jun;11(3):343-8 20544831 - J Neurosci Res. 2010 Nov 1;88(14):2991-3001 Kesner (10.1016/j.neuron.2013.10.033_bib19) 2010; 20 Müller (10.1016/j.neuron.2013.10.033_bib40) 2012; 75 Kim (10.1016/j.neuron.2013.10.033_bib20) 2012; 15 Mizuseki (10.1016/j.neuron.2013.10.033_bib39) 2012; 22 Polsky (10.1016/j.neuron.2013.10.033_bib45) 2009; 29 Ranck (10.1016/j.neuron.2013.10.033_bib46) 1973; 41 Sanders (10.1016/j.neuron.2013.10.033_bib49) 2013; 33 Buzsáki (10.1016/j.neuron.2013.10.033_bib7) 2010; 68 Amaral (10.1016/j.neuron.2013.10.033_bib1) 1989; 31 Lavzin (10.1016/j.neuron.2013.10.033_bib26) 2012; 490 Ngo-Anh (10.1016/j.neuron.2013.10.033_bib42) 2005; 8 Spruston (10.1016/j.neuron.2013.10.033_bib55) 1995; 482 Remy (10.1016/j.neuron.2013.10.033_bib47) 2009; 61 Sjöström (10.1016/j.neuron.2013.10.033_bib53) 2008; 88 Chen (10.1016/j.neuron.2013.10.033_bib8) 2005; 25 Antic (10.1016/j.neuron.2013.10.033_bib2) 2010; 88 Gasparini (10.1016/j.neuron.2013.10.033_bib13) 2007; 580 Sodickson (10.1016/j.neuron.2013.10.033_bib54) 1996; 16 Urban (10.1016/j.neuron.2013.10.033_bib60) 1998; 95 Breton (10.1016/j.neuron.2013.10.033_bib5) 2012; 108 Krueppel (10.1016/j.neuron.2013.10.033_bib23) 2011; 71 Frick (10.1016/j.neuron.2013.10.033_bib11) 2004; 7 Schiller (10.1016/j.neuron.2013.10.033_bib50) 2001; 11 Guzowski (10.1016/j.neuron.2013.10.033_bib16) 2004; 44 Lee (10.1016/j.neuron.2013.10.033_bib27) 2004; 430 Larkum (10.1016/j.neuron.2013.10.033_bib25) 2009; 325 Koyrakh (10.1016/j.neuron.2013.10.033_bib22) 2005; 25 Miles (10.1016/j.neuron.2013.10.033_bib38) 1986; 373 Branco (10.1016/j.neuron.2013.10.033_bib4) 2010; 329 Lüscher (10.1016/j.neuron.2013.10.033_bib32) 2010; 11 Fellini (10.1016/j.neuron.2013.10.033_bib10) 2009; 16 Gulledge (10.1016/j.neuron.2013.10.033_bib15) 2005; 64 O’Neill (10.1016/j.neuron.2013.10.033_bib43) 2010; 33 Gähwiler (10.1016/j.neuron.2013.10.033_bib12) 1985; 82 Jin (10.1016/j.neuron.2013.10.033_bib18) 1999; 38 Buckmaster (10.1016/j.neuron.2013.10.033_bib6) 2001; 430 Treves (10.1016/j.neuron.2013.10.033_bib59) 1994; 4 Gold (10.1016/j.neuron.2013.10.033_bib14) 2005; 15 Ariav (10.1016/j.neuron.2013.10.033_bib3) 2003; 23 Makara (10.1016/j.neuron.2013.10.033_bib35) 2009; 12 Kulik (10.1016/j.neuron.2013.10.033_bib24) 2006; 26 Kleindienst (10.1016/j.neuron.2013.10.033_bib21) 2011; 72 Storm (10.1016/j.neuron.2013.10.033_bib56) 1990; 83 Marr (10.1016/j.neuron.2013.10.033_bib36) 1971; 262 Losonczy (10.1016/j.neuron.2013.10.033_bib31) 2008; 452 Palmer (10.1016/j.neuron.2013.10.033_bib44) 2012; 335 Magee (10.1016/j.neuron.2013.10.033_bib34) 2005; 15 Rolls (10.1016/j.neuron.2013.10.033_bib48) 2006; 79 Schiller (10.1016/j.neuron.2013.10.033_bib51) 2000; 404 Lüscher (10.1016/j.neuron.2013.10.033_bib33) 1997; 19 Takahashi (10.1016/j.neuron.2013.10.033_bib57) 2012; 335 McNaughton (10.1016/j.neuron.2013.10.033_bib37) 1987; 10 Takigawa (10.1016/j.neuron.2013.10.033_bib58) 1999; 517 Shah (10.1016/j.neuron.2013.10.033_bib52) 2010; 33 Li (10.1016/j.neuron.2013.10.033_bib29) 1994; 339 Losonczy (10.1016/j.neuron.2013.10.033_bib30) 2006; 50 Nakazawa (10.1016/j.neuron.2013.10.033_bib41) 2002; 297 Coetzee (10.1016/j.neuron.2013.10.033_bib9) 1999; 868 Wessel (10.1016/j.neuron.2013.10.033_bib61) 1999; 19 Legenstein (10.1016/j.neuron.2013.10.033_bib28) 2011; 31 Hibino (10.1016/j.neuron.2013.10.033_bib17) 2010; 90 |
References_xml | – volume: 64 start-page: 75 year: 2005 end-page: 90 ident: bib15 article-title: Synaptic integration in dendritic trees publication-title: J. Neurobiol. contributor: fullname: Stuart – volume: 868 start-page: 233 year: 1999 end-page: 285 ident: bib9 article-title: Molecular diversity of K+ channels publication-title: Ann. N Y Acad. Sci. contributor: fullname: Pountney – volume: 33 start-page: 220 year: 2010 end-page: 229 ident: bib43 article-title: Play it again: reactivation of waking experience and memory publication-title: Trends Neurosci. contributor: fullname: Csicsvari – volume: 490 start-page: 397 year: 2012 end-page: 401 ident: bib26 article-title: Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo publication-title: Nature contributor: fullname: Schiller – volume: 82 start-page: 1558 year: 1985 end-page: 1562 ident: bib12 article-title: GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Brown – volume: 11 start-page: 343 year: 2001 end-page: 348 ident: bib50 article-title: NMDA receptor-mediated dendritic spikes and coincident signal amplification publication-title: Curr. Opin. Neurobiol. contributor: fullname: Schiller – volume: 31 start-page: 571 year: 1989 end-page: 591 ident: bib1 article-title: The three-dimensional organization of the hippocampal formation: a review of anatomical data publication-title: Neuroscience contributor: fullname: Witter – volume: 482 start-page: 325 year: 1995 end-page: 352 ident: bib55 article-title: Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons publication-title: J. Physiol. contributor: fullname: Sakmann – volume: 335 start-page: 353 year: 2012 end-page: 356 ident: bib57 article-title: Locally synchronized synaptic inputs publication-title: Science contributor: fullname: Ikegaya – volume: 8 start-page: 642 year: 2005 end-page: 649 ident: bib42 article-title: SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines publication-title: Nat. Neurosci. contributor: fullname: Adelman – volume: 16 start-page: 6374 year: 1996 end-page: 6385 ident: bib54 article-title: GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons publication-title: J. Neurosci. contributor: fullname: Bean – volume: 339 start-page: 181 year: 1994 end-page: 208 ident: bib29 article-title: The hippocampal CA3 network: an in vivo intracellular labeling study publication-title: J. Comp. Neurol. contributor: fullname: Buzsáki – volume: 404 start-page: 285 year: 2000 end-page: 289 ident: bib51 article-title: NMDA spikes in basal dendrites of cortical pyramidal neurons publication-title: Nature contributor: fullname: Schiller – volume: 90 start-page: 291 year: 2010 end-page: 366 ident: bib17 article-title: Inwardly rectifying potassium channels: their structure, function, and physiological roles publication-title: Physiol. Rev. contributor: fullname: Kurachi – volume: 29 start-page: 11891 year: 2009 end-page: 11903 ident: bib45 article-title: Encoding and decoding bursts by NMDA spikes in basal dendrites of layer 5 pyramidal neurons publication-title: J. Neurosci. contributor: fullname: Schiller – volume: 88 start-page: 2991 year: 2010 end-page: 3001 ident: bib2 article-title: The decade of the dendritic NMDA spike publication-title: J. Neurosci. Res. contributor: fullname: Ikonomu – volume: 15 start-page: 600 year: 2012 end-page: 606 ident: bib20 article-title: Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons publication-title: Nat. Neurosci. contributor: fullname: Jonas – volume: 373 start-page: 397 year: 1986 end-page: 418 ident: bib38 article-title: Excitatory synaptic interactions between CA3 neurones in the guinea-pig hippocampus publication-title: J. Physiol. contributor: fullname: Wong – volume: 108 start-page: 2810 year: 2012 end-page: 2818 ident: bib5 article-title: Somatic and dendritic GABA(B) receptors regulate neuronal excitability via different mechanisms publication-title: J. Neurophysiol. contributor: fullname: Stuart – volume: 19 start-page: 687 year: 1997 end-page: 695 ident: bib33 article-title: G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons publication-title: Neuron contributor: fullname: Nicoll – volume: 25 start-page: 11468 year: 2005 end-page: 11478 ident: bib22 article-title: Molecular and cellular diversity of neuronal G-protein-gated potassium channels publication-title: J. Neurosci. contributor: fullname: Wickman – volume: 68 start-page: 362 year: 2010 end-page: 385 ident: bib7 article-title: Neural syntax: cell assemblies, synapsembles, and readers publication-title: Neuron contributor: fullname: Buzsáki – volume: 16 start-page: 387 year: 2009 end-page: 394 ident: bib10 article-title: Pharmacological intervention of hippocampal CA3 NMDA receptors impairs acquisition and long-term memory retrieval of spatial pattern completion task publication-title: Learn. Mem. contributor: fullname: Roullet – volume: 44 start-page: 581 year: 2004 end-page: 584 ident: bib16 article-title: Ensemble dynamics of hippocampal regions CA3 and CA1 publication-title: Neuron contributor: fullname: Moser – volume: 22 start-page: 1659 year: 2012 end-page: 1680 ident: bib39 article-title: Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons publication-title: Hippocampus contributor: fullname: Buzsáki – volume: 75 start-page: 851 year: 2012 end-page: 864 ident: bib40 article-title: Inhibitory control of linear and supralinear dendritic excitation in CA1 pyramidal neurons publication-title: Neuron contributor: fullname: Remy – volume: 517 start-page: 385 year: 1999 end-page: 390 ident: bib58 article-title: G protein-activated inwardly rectifying K+ (GIRK) currents in dendrites of rat neocortical pyramidal cells publication-title: J. Physiol. contributor: fullname: Alzheimer – volume: 19 start-page: 5875 year: 1999 end-page: 5888 ident: bib61 article-title: Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an “inward rectifier” K(+) current publication-title: J. Neurosci. contributor: fullname: Kleinfeld – volume: 15 start-page: 808 year: 2005 end-page: 814 ident: bib14 article-title: The role of the CA3 subregion of the dorsal hippocampus in spatial pattern completion in the rat publication-title: Hippocampus contributor: fullname: Kesner – volume: 61 start-page: 906 year: 2009 end-page: 916 ident: bib47 article-title: Activity-dependent control of neuronal output by local and global dendritic spike attenuation publication-title: Neuron contributor: fullname: Beck – volume: 83 start-page: 161 year: 1990 end-page: 187 ident: bib56 article-title: Potassium currents in hippocampal pyramidal cells publication-title: Prog. Brain Res. contributor: fullname: Storm – volume: 95 start-page: 11450 year: 1998 end-page: 11455 ident: bib60 article-title: Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons publication-title: Proc. Natl. Acad. Sci. USA contributor: fullname: Barrionuevo – volume: 580 start-page: 787 year: 2007 end-page: 800 ident: bib13 article-title: Associative pairing enhances action potential back-propagation in radial oblique branches of CA1 pyramidal neurons publication-title: J. Physiol. contributor: fullname: Magee – volume: 88 start-page: 769 year: 2008 end-page: 840 ident: bib53 article-title: Dendritic excitability and synaptic plasticity publication-title: Physiol. Rev. contributor: fullname: Häusser – volume: 23 start-page: 7750 year: 2003 end-page: 7758 ident: bib3 article-title: Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons publication-title: J. Neurosci. contributor: fullname: Schiller – volume: 335 start-page: 989 year: 2012 end-page: 993 ident: bib44 article-title: The cellular basis of GABA(B)-mediated interhemispheric inhibition publication-title: Science contributor: fullname: Larkum – volume: 430 start-page: 456 year: 2004 end-page: 459 ident: bib27 article-title: Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3 publication-title: Nature contributor: fullname: Knierim – volume: 10 start-page: 408 year: 1987 end-page: 415 ident: bib37 article-title: Hippocampal synaptic enhancement and information storage within a distributed memory system publication-title: Trends Neurosci. contributor: fullname: Morris – volume: 15 start-page: 334 year: 2005 end-page: 342 ident: bib34 article-title: Plasticity of dendritic function publication-title: Curr. Opin. Neurobiol. contributor: fullname: Johnston – volume: 452 start-page: 436 year: 2008 end-page: 441 ident: bib31 article-title: Compartmentalized dendritic plasticity and input feature storage in neurons publication-title: Nature contributor: fullname: Magee – volume: 20 start-page: 550 year: 2010 end-page: 557 ident: bib19 article-title: Implications of CA3 NMDA and opiate receptors for spatial pattern completion in rats publication-title: Hippocampus contributor: fullname: Warthen – volume: 33 start-page: 424 year: 2013 end-page: 429 ident: bib49 article-title: NMDA and GABAB (KIR) conductances: the “perfect couple” for bistability publication-title: J. Neurosci. contributor: fullname: Lisman – volume: 41 start-page: 461 year: 1973 end-page: 531 ident: bib46 article-title: Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires publication-title: Exp. Neurol. contributor: fullname: Ranck – volume: 25 start-page: 3787 year: 2005 end-page: 3792 ident: bib8 article-title: Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons publication-title: J. Neurosci. contributor: fullname: Johnston – volume: 325 start-page: 756 year: 2009 end-page: 760 ident: bib25 article-title: Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle publication-title: Science contributor: fullname: Schiller – volume: 72 start-page: 1012 year: 2011 end-page: 1024 ident: bib21 article-title: Activity-dependent clustering of functional synaptic inputs on developing hippocampal dendrites publication-title: Neuron contributor: fullname: Lohmann – volume: 33 start-page: 307 year: 2010 end-page: 316 ident: bib52 article-title: Dendritic ion channel trafficking and plasticity publication-title: Trends Neurosci. contributor: fullname: Hoffman – volume: 262 start-page: 23 year: 1971 end-page: 81 ident: bib36 article-title: Simple memory: a theory for archicortex publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. contributor: fullname: Marr – volume: 50 start-page: 291 year: 2006 end-page: 307 ident: bib30 article-title: Integrative properties of radial oblique dendrites in hippocampal CA1 pyramidal neurons publication-title: Neuron contributor: fullname: Magee – volume: 4 start-page: 374 year: 1994 end-page: 391 ident: bib59 article-title: Computational analysis of the role of the hippocampus in memory publication-title: Hippocampus contributor: fullname: Rolls – volume: 329 start-page: 1671 year: 2010 end-page: 1675 ident: bib4 article-title: Dendritic discrimination of temporal input sequences in cortical neurons publication-title: Science contributor: fullname: Häusser – volume: 430 start-page: 264 year: 2001 end-page: 281 ident: bib6 article-title: Intracellular recording and labeling of mossy cells and proximal CA3 pyramidal cells in macaque monkeys publication-title: J. Comp. Neurol. contributor: fullname: Amaral – volume: 297 start-page: 211 year: 2002 end-page: 218 ident: bib41 article-title: Requirement for hippocampal CA3 NMDA receptors in associative memory recall publication-title: Science contributor: fullname: Tonegawa – volume: 71 start-page: 512 year: 2011 end-page: 528 ident: bib23 article-title: Dendritic integration in hippocampal dentate granule cells publication-title: Neuron contributor: fullname: Beck – volume: 7 start-page: 126 year: 2004 end-page: 135 ident: bib11 article-title: LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites publication-title: Nat. Neurosci. contributor: fullname: Johnston – volume: 38 start-page: 14286 year: 1999 end-page: 14293 ident: bib18 article-title: Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels publication-title: Biochemistry contributor: fullname: Lu – volume: 26 start-page: 4289 year: 2006 end-page: 4297 ident: bib24 article-title: Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells publication-title: J. Neurosc contributor: fullname: Shigemoto – volume: 11 start-page: 301 year: 2010 end-page: 315 ident: bib32 article-title: Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease publication-title: Nat. Rev. Neurosci. contributor: fullname: Slesinger – volume: 31 start-page: 10787 year: 2011 end-page: 10802 ident: bib28 article-title: Branch-specific plasticity enables self-organization of nonlinear computation in single neurons publication-title: J. Neurosci. contributor: fullname: Maass – volume: 79 start-page: 1 year: 2006 end-page: 48 ident: bib48 article-title: A computational theory of hippocampal function, and empirical tests of the theory publication-title: Prog. Neurobiol. contributor: fullname: Kesner – volume: 12 start-page: 1485 year: 2009 end-page: 1487 ident: bib35 article-title: Experience-dependent compartmentalized dendritic plasticity in rat hippocampal CA1 pyramidal neurons publication-title: Nat. Neurosci. contributor: fullname: Magee – volume: 430 start-page: 456 year: 2004 ident: 10.1016/j.neuron.2013.10.033_bib27 article-title: Comparison of population coherence of place cells in hippocampal subfields CA1 and CA3 publication-title: Nature doi: 10.1038/nature02739 contributor: fullname: Lee – volume: 335 start-page: 353 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib57 article-title: Locally synchronized synaptic inputs publication-title: Science doi: 10.1126/science.1210362 contributor: fullname: Takahashi – volume: 31 start-page: 10787 year: 2011 ident: 10.1016/j.neuron.2013.10.033_bib28 article-title: Branch-specific plasticity enables self-organization of nonlinear computation in single neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.5684-10.2011 contributor: fullname: Legenstein – volume: 329 start-page: 1671 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib4 article-title: Dendritic discrimination of temporal input sequences in cortical neurons publication-title: Science doi: 10.1126/science.1189664 contributor: fullname: Branco – volume: 26 start-page: 4289 year: 2006 ident: 10.1016/j.neuron.2013.10.033_bib24 article-title: Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells publication-title: J. Neurosc doi: 10.1523/JNEUROSCI.4178-05.2006 contributor: fullname: Kulik – volume: 75 start-page: 851 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib40 article-title: Inhibitory control of linear and supralinear dendritic excitation in CA1 pyramidal neurons publication-title: Neuron doi: 10.1016/j.neuron.2012.06.025 contributor: fullname: Müller – volume: 19 start-page: 687 year: 1997 ident: 10.1016/j.neuron.2013.10.033_bib33 article-title: G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons publication-title: Neuron doi: 10.1016/S0896-6273(00)80381-5 contributor: fullname: Lüscher – volume: 20 start-page: 550 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib19 article-title: Implications of CA3 NMDA and opiate receptors for spatial pattern completion in rats publication-title: Hippocampus doi: 10.1002/hipo.20676 contributor: fullname: Kesner – volume: 64 start-page: 75 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib15 article-title: Synaptic integration in dendritic trees publication-title: J. Neurobiol. doi: 10.1002/neu.20144 contributor: fullname: Gulledge – volume: 82 start-page: 1558 year: 1985 ident: 10.1016/j.neuron.2013.10.033_bib12 article-title: GABAB-receptor-activated K+ current in voltage-clamped CA3 pyramidal cells in hippocampal cultures publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.82.5.1558 contributor: fullname: Gähwiler – volume: 90 start-page: 291 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib17 article-title: Inwardly rectifying potassium channels: their structure, function, and physiological roles publication-title: Physiol. Rev. doi: 10.1152/physrev.00021.2009 contributor: fullname: Hibino – volume: 71 start-page: 512 year: 2011 ident: 10.1016/j.neuron.2013.10.033_bib23 article-title: Dendritic integration in hippocampal dentate granule cells publication-title: Neuron doi: 10.1016/j.neuron.2011.05.043 contributor: fullname: Krueppel – volume: 29 start-page: 11891 year: 2009 ident: 10.1016/j.neuron.2013.10.033_bib45 article-title: Encoding and decoding bursts by NMDA spikes in basal dendrites of layer 5 pyramidal neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.5250-08.2009 contributor: fullname: Polsky – volume: 373 start-page: 397 year: 1986 ident: 10.1016/j.neuron.2013.10.033_bib38 article-title: Excitatory synaptic interactions between CA3 neurones in the guinea-pig hippocampus publication-title: J. Physiol. doi: 10.1113/jphysiol.1986.sp016055 contributor: fullname: Miles – volume: 25 start-page: 11468 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib22 article-title: Molecular and cellular diversity of neuronal G-protein-gated potassium channels publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.3484-05.2005 contributor: fullname: Koyrakh – volume: 10 start-page: 408 year: 1987 ident: 10.1016/j.neuron.2013.10.033_bib37 article-title: Hippocampal synaptic enhancement and information storage within a distributed memory system publication-title: Trends Neurosci. doi: 10.1016/0166-2236(87)90011-7 contributor: fullname: McNaughton – volume: 108 start-page: 2810 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib5 article-title: Somatic and dendritic GABA(B) receptors regulate neuronal excitability via different mechanisms publication-title: J. Neurophysiol. doi: 10.1152/jn.00524.2012 contributor: fullname: Breton – volume: 23 start-page: 7750 year: 2003 ident: 10.1016/j.neuron.2013.10.033_bib3 article-title: Submillisecond precision of the input-output transformation function mediated by fast sodium dendritic spikes in basal dendrites of CA1 pyramidal neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.23-21-07750.2003 contributor: fullname: Ariav – volume: 16 start-page: 387 year: 2009 ident: 10.1016/j.neuron.2013.10.033_bib10 article-title: Pharmacological intervention of hippocampal CA3 NMDA receptors impairs acquisition and long-term memory retrieval of spatial pattern completion task publication-title: Learn. Mem. doi: 10.1101/lm.1433209 contributor: fullname: Fellini – volume: 8 start-page: 642 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib42 article-title: SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines publication-title: Nat. Neurosci. doi: 10.1038/nn1449 contributor: fullname: Ngo-Anh – volume: 33 start-page: 307 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib52 article-title: Dendritic ion channel trafficking and plasticity publication-title: Trends Neurosci. doi: 10.1016/j.tins.2010.03.002 contributor: fullname: Shah – volume: 15 start-page: 600 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib20 article-title: Active dendrites support efficient initiation of dendritic spikes in hippocampal CA3 pyramidal neurons publication-title: Nat. Neurosci. doi: 10.1038/nn.3060 contributor: fullname: Kim – volume: 404 start-page: 285 year: 2000 ident: 10.1016/j.neuron.2013.10.033_bib51 article-title: NMDA spikes in basal dendrites of cortical pyramidal neurons publication-title: Nature doi: 10.1038/35005094 contributor: fullname: Schiller – volume: 95 start-page: 11450 year: 1998 ident: 10.1016/j.neuron.2013.10.033_bib60 article-title: Active summation of excitatory postsynaptic potentials in hippocampal CA3 pyramidal neurons publication-title: Proc. Natl. Acad. Sci. USA doi: 10.1073/pnas.95.19.11450 contributor: fullname: Urban – volume: 868 start-page: 233 year: 1999 ident: 10.1016/j.neuron.2013.10.033_bib9 article-title: Molecular diversity of K+ channels publication-title: Ann. N Y Acad. Sci. doi: 10.1111/j.1749-6632.1999.tb11293.x contributor: fullname: Coetzee – volume: 41 start-page: 461 year: 1973 ident: 10.1016/j.neuron.2013.10.033_bib46 article-title: Studies on single neurons in dorsal hippocampal formation and septum in unrestrained rats. I. Behavioral correlates and firing repertoires publication-title: Exp. Neurol. doi: 10.1016/0014-4886(73)90290-2 contributor: fullname: Ranck – volume: 88 start-page: 769 year: 2008 ident: 10.1016/j.neuron.2013.10.033_bib53 article-title: Dendritic excitability and synaptic plasticity publication-title: Physiol. Rev. doi: 10.1152/physrev.00016.2007 contributor: fullname: Sjöström – volume: 7 start-page: 126 year: 2004 ident: 10.1016/j.neuron.2013.10.033_bib11 article-title: LTP is accompanied by an enhanced local excitability of pyramidal neuron dendrites publication-title: Nat. Neurosci. doi: 10.1038/nn1178 contributor: fullname: Frick – volume: 262 start-page: 23 year: 1971 ident: 10.1016/j.neuron.2013.10.033_bib36 article-title: Simple memory: a theory for archicortex publication-title: Philos. Trans. R. Soc. Lond. B Biol. Sci. doi: 10.1098/rstb.1971.0078 contributor: fullname: Marr – volume: 33 start-page: 424 year: 2013 ident: 10.1016/j.neuron.2013.10.033_bib49 article-title: NMDA and GABAB (KIR) conductances: the “perfect couple” for bistability publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.1854-12.2013 contributor: fullname: Sanders – volume: 79 start-page: 1 year: 2006 ident: 10.1016/j.neuron.2013.10.033_bib48 article-title: A computational theory of hippocampal function, and empirical tests of the theory publication-title: Prog. Neurobiol. doi: 10.1016/j.pneurobio.2006.04.005 contributor: fullname: Rolls – volume: 297 start-page: 211 year: 2002 ident: 10.1016/j.neuron.2013.10.033_bib41 article-title: Requirement for hippocampal CA3 NMDA receptors in associative memory recall publication-title: Science doi: 10.1126/science.1071795 contributor: fullname: Nakazawa – volume: 335 start-page: 989 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib44 article-title: The cellular basis of GABA(B)-mediated interhemispheric inhibition publication-title: Science doi: 10.1126/science.1217276 contributor: fullname: Palmer – volume: 11 start-page: 343 year: 2001 ident: 10.1016/j.neuron.2013.10.033_bib50 article-title: NMDA receptor-mediated dendritic spikes and coincident signal amplification publication-title: Curr. Opin. Neurobiol. doi: 10.1016/S0959-4388(00)00217-8 contributor: fullname: Schiller – volume: 15 start-page: 334 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib34 article-title: Plasticity of dendritic function publication-title: Curr. Opin. Neurobiol. doi: 10.1016/j.conb.2005.05.013 contributor: fullname: Magee – volume: 68 start-page: 362 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib7 article-title: Neural syntax: cell assemblies, synapsembles, and readers publication-title: Neuron doi: 10.1016/j.neuron.2010.09.023 contributor: fullname: Buzsáki – volume: 16 start-page: 6374 year: 1996 ident: 10.1016/j.neuron.2013.10.033_bib54 article-title: GABAB receptor-activated inwardly rectifying potassium current in dissociated hippocampal CA3 neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.16-20-06374.1996 contributor: fullname: Sodickson – volume: 50 start-page: 291 year: 2006 ident: 10.1016/j.neuron.2013.10.033_bib30 article-title: Integrative properties of radial oblique dendrites in hippocampal CA1 pyramidal neurons publication-title: Neuron doi: 10.1016/j.neuron.2006.03.016 contributor: fullname: Losonczy – volume: 33 start-page: 220 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib43 article-title: Play it again: reactivation of waking experience and memory publication-title: Trends Neurosci. doi: 10.1016/j.tins.2010.01.006 contributor: fullname: O’Neill – volume: 61 start-page: 906 year: 2009 ident: 10.1016/j.neuron.2013.10.033_bib47 article-title: Activity-dependent control of neuronal output by local and global dendritic spike attenuation publication-title: Neuron doi: 10.1016/j.neuron.2009.01.032 contributor: fullname: Remy – volume: 325 start-page: 756 year: 2009 ident: 10.1016/j.neuron.2013.10.033_bib25 article-title: Synaptic integration in tuft dendrites of layer 5 pyramidal neurons: a new unifying principle publication-title: Science doi: 10.1126/science.1171958 contributor: fullname: Larkum – volume: 4 start-page: 374 year: 1994 ident: 10.1016/j.neuron.2013.10.033_bib59 article-title: Computational analysis of the role of the hippocampus in memory publication-title: Hippocampus doi: 10.1002/hipo.450040319 contributor: fullname: Treves – volume: 88 start-page: 2991 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib2 article-title: The decade of the dendritic NMDA spike publication-title: J. Neurosci. Res. doi: 10.1002/jnr.22444 contributor: fullname: Antic – volume: 38 start-page: 14286 year: 1999 ident: 10.1016/j.neuron.2013.10.033_bib18 article-title: Synthesis of a stable form of tertiapin: a high-affinity inhibitor for inward-rectifier K+ channels publication-title: Biochemistry doi: 10.1021/bi991205r contributor: fullname: Jin – volume: 72 start-page: 1012 year: 2011 ident: 10.1016/j.neuron.2013.10.033_bib21 article-title: Activity-dependent clustering of functional synaptic inputs on developing hippocampal dendrites publication-title: Neuron doi: 10.1016/j.neuron.2011.10.015 contributor: fullname: Kleindienst – volume: 517 start-page: 385 year: 1999 ident: 10.1016/j.neuron.2013.10.033_bib58 article-title: G protein-activated inwardly rectifying K+ (GIRK) currents in dendrites of rat neocortical pyramidal cells publication-title: J. Physiol. doi: 10.1111/j.1469-7793.1999.0385t.x contributor: fullname: Takigawa – volume: 430 start-page: 264 year: 2001 ident: 10.1016/j.neuron.2013.10.033_bib6 article-title: Intracellular recording and labeling of mossy cells and proximal CA3 pyramidal cells in macaque monkeys publication-title: J. Comp. Neurol. doi: 10.1002/1096-9861(20010205)430:2<264::AID-CNE1030>3.0.CO;2-3 contributor: fullname: Buckmaster – volume: 83 start-page: 161 year: 1990 ident: 10.1016/j.neuron.2013.10.033_bib56 article-title: Potassium currents in hippocampal pyramidal cells publication-title: Prog. Brain Res. doi: 10.1016/S0079-6123(08)61248-0 contributor: fullname: Storm – volume: 15 start-page: 808 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib14 article-title: The role of the CA3 subregion of the dorsal hippocampus in spatial pattern completion in the rat publication-title: Hippocampus doi: 10.1002/hipo.20103 contributor: fullname: Gold – volume: 12 start-page: 1485 year: 2009 ident: 10.1016/j.neuron.2013.10.033_bib35 article-title: Experience-dependent compartmentalized dendritic plasticity in rat hippocampal CA1 pyramidal neurons publication-title: Nat. Neurosci. doi: 10.1038/nn.2428 contributor: fullname: Makara – volume: 11 start-page: 301 year: 2010 ident: 10.1016/j.neuron.2013.10.033_bib32 article-title: Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn2834 contributor: fullname: Lüscher – volume: 22 start-page: 1659 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib39 article-title: Activity dynamics and behavioral correlates of CA3 and CA1 hippocampal pyramidal neurons publication-title: Hippocampus doi: 10.1002/hipo.22002 contributor: fullname: Mizuseki – volume: 25 start-page: 3787 year: 2005 ident: 10.1016/j.neuron.2013.10.033_bib8 article-title: Constitutively active G-protein-gated inwardly rectifying K+ channels in dendrites of hippocampal CA1 pyramidal neurons publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.5312-04.2005 contributor: fullname: Chen – volume: 44 start-page: 581 year: 2004 ident: 10.1016/j.neuron.2013.10.033_bib16 article-title: Ensemble dynamics of hippocampal regions CA3 and CA1 publication-title: Neuron doi: 10.1016/j.neuron.2004.11.003 contributor: fullname: Guzowski – volume: 31 start-page: 571 year: 1989 ident: 10.1016/j.neuron.2013.10.033_bib1 article-title: The three-dimensional organization of the hippocampal formation: a review of anatomical data publication-title: Neuroscience doi: 10.1016/0306-4522(89)90424-7 contributor: fullname: Amaral – volume: 490 start-page: 397 year: 2012 ident: 10.1016/j.neuron.2013.10.033_bib26 article-title: Nonlinear dendritic processing determines angular tuning of barrel cortex neurons in vivo publication-title: Nature doi: 10.1038/nature11451 contributor: fullname: Lavzin – volume: 482 start-page: 325 year: 1995 ident: 10.1016/j.neuron.2013.10.033_bib55 article-title: Dendritic glutamate receptor channels in rat hippocampal CA3 and CA1 pyramidal neurons publication-title: J. Physiol. doi: 10.1113/jphysiol.1995.sp020521 contributor: fullname: Spruston – volume: 339 start-page: 181 year: 1994 ident: 10.1016/j.neuron.2013.10.033_bib29 article-title: The hippocampal CA3 network: an in vivo intracellular labeling study publication-title: J. Comp. Neurol. doi: 10.1002/cne.903390204 contributor: fullname: Li – volume: 19 start-page: 5875 year: 1999 ident: 10.1016/j.neuron.2013.10.033_bib61 article-title: Supralinear summation of synaptic inputs by an invertebrate neuron: dendritic gain is mediated by an “inward rectifier” K(+) current publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.19-14-05875.1999 contributor: fullname: Wessel – volume: 452 start-page: 436 year: 2008 ident: 10.1016/j.neuron.2013.10.033_bib31 article-title: Compartmentalized dendritic plasticity and input feature storage in neurons publication-title: Nature doi: 10.1038/nature06725 contributor: fullname: Losonczy – volume: 580 start-page: 787 year: 2007 ident: 10.1016/j.neuron.2013.10.033_bib13 article-title: Associative pairing enhances action potential back-propagation in radial oblique branches of CA1 pyramidal neurons publication-title: J. Physiol. doi: 10.1113/jphysiol.2006.121343 contributor: fullname: Gasparini |
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SubjectTerms | Action Potentials - physiology Animals Brain CA3 Region, Hippocampal - physiology Dendrites - physiology Experiments G Protein-Coupled Inwardly-Rectifying Potassium Channels - physiology Glutamic Acid - pharmacology Male N-Methylaspartate - physiology Neurons Potassium Channels Pyramidal Cells - physiology Rats Sodium - physiology |
Title | Variable Dendritic Integration in Hippocampal CA3 Pyramidal Neurons |
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