Clinical Trial Technologies for Improving Equity and Inclusion in Cardiovascular Clinical Research

Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the scientific integrity and generalizability of a trial. Inadequate recruitment and retention of patient groups who have the disease under investigation may prod...

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Published inCardiology and Therapy Vol. 12; no. 2; pp. 215 - 225
Main Authors Broadwin, Cassandra, Azizi, Zahra, Rodriguez, Fatima
Format Journal Article
LanguageEnglish
Published Cheshire Springer Healthcare 01.06.2023
Springer
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Abstract Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the scientific integrity and generalizability of a trial. Inadequate recruitment and retention of patient groups who have the disease under investigation may produce insufficient medical knowledge about the therapeutic effects of drugs or products for the population at large. It is essential to address these issues to ensure that certain groups are not unduly subjected to disproportionate risks or denied the benefits of research. This commentary will present opportunities for clinical trialists to use emerging technologies and decentralized approaches to improve clinical trial recruitment, mitigate disparities, and improve individual and population-level outcomes within cardiovascular medicine.
AbstractList Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the scientific integrity and generalizability of a trial. Inadequate recruitment and retention of patient groups who have the disease under investigation may produce insufficient medical knowledge about the therapeutic effects of drugs or products for the population at large. It is essential to address these issues to ensure that certain groups are not unduly subjected to disproportionate risks or denied the benefits of research. This commentary will present opportunities for clinical trialists to use emerging technologies and decentralized approaches to improve clinical trial recruitment, mitigate disparities, and improve individual and population-level outcomes within cardiovascular medicine.
Abstract Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the scientific integrity and generalizability of a trial. Inadequate recruitment and retention of patient groups who have the disease under investigation may produce insufficient medical knowledge about the therapeutic effects of drugs or products for the population at large. It is essential to address these issues to ensure that certain groups are not unduly subjected to disproportionate risks or denied the benefits of research. This commentary will present opportunities for clinical trialists to use emerging technologies and decentralized approaches to improve clinical trial recruitment, mitigate disparities, and improve individual and population-level outcomes within cardiovascular medicine.
Audience Academic
Author Rodriguez, Fatima
Azizi, Zahra
Broadwin, Cassandra
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Cites_doi 10.1001/jama.2022.0875
10.1007/s12265-009-9114-9
10.1093/eurjcn/zvab119
10.1093/eurheartj/ehy377
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Issue 2
Keywords Health equity
Diversity and inclusion
Racial disparities
Cardiology
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Snippet Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the scientific...
Abstract Approximately one-third of clinical trials fail to meet their recruitment goals, which can cause costly delays to sponsors and compromise the...
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SubjectTerms Cardiology
Cardiovascular research
Clinical trials
Commentary
Diversity and inclusion
Health care disparities
Health equity
Internal Medicine
Medicine
Medicine & Public Health
Prevention
Quality management
Racial disparities
Social aspects
Technology application
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Title Clinical Trial Technologies for Improving Equity and Inclusion in Cardiovascular Clinical Research
URI https://link.springer.com/article/10.1007/s40119-023-00311-y
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Volume 12
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