Altered glycosylation profiles of serum IgG in Takayasu arteritis

• Published in: European journal of medical research Vol. 28; no. 1; pp. 69 - 9
• Main Authors: Liu, Lingyu, Li, Jing, Yang, Yunjiao, Hu, Chaojun, Tian, Xinping
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08.02.2023; BioMed Central; BMC
• Subjects: Analysis; Antibodies; Atherosclerosis; Autoimmune diseases; B cells; Chronic illnesses; Communications equipment; Development and progression; Disease; DNA microarrays; Gender; Glycosylation; Humans; Immunoglobulin G; Laboratories; Lectin microarray; Lectins; Lectins - metabolism; Pathogenesis; Proteins; Software; Somatotropin; Takayasu Arteritis; Vein & artery diseases; Veins & arteries; Thailand; Illinois; China; Taiwan; United States > US; Lectin microarray; Glycosylation; Takayasu arteritis; Immunoglobulin G

Takayasu arteritis (TAK) is an autoimmune inflammatory disorder with an undefined etiology. This study aimed to characterize the glycosylation profiles of serum immunoglobulin G (IgG) in patients with TAK. Lectin microarrays containing 56 types of lectins were used to detect the glycan levels of ser...