Impact of the New Definition of Metabolic Associated Fatty Liver Disease on the Epidemiology of the Disease

• Published in: Clinical gastroenterology and hepatology Vol. 19; no. 10; pp. 2161 - 2171.e5
• Main Authors: Wong, Vincent Wai-Sun, Wong, Grace Lai-Hung, Woo, Jean, Abrigo, Jill M., Chan, Carmen Ka-Man, Shu, Sally She-Ting, Leung, Julie Ka-Yu, Chim, Angel Mei-Ling, Kong, Alice Pik-Shan, Lui, Grace Chung-Yan, Chan, Henry Lik-Yuen, Chu, Winnie Chiu-Wing
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2021
• Subjects: Adult; Diabetes Mellitus; Elasticity Imaging Techniques; Gastroenterology and Hepatology; Humans; Incidence; Magnetic Resonance Spectroscopy; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease - complications; Non-alcoholic Fatty Liver Disease - epidemiology; Nonalcoholic Fatty Liver Disease; Nonalcoholic Steatohepatitis; Prevalence; Transient Elastography; AST; NAFLD; Magnetic Resonance Spectroscopy; Transient Elastography; CI; ALT; HCC; IHTG; 1H-MRS; MAFLD; Metabolic Syndrome; Nonalcoholic Fatty Liver Disease; APRI; FIB-4; HbA1c; Nonalcoholic Steatohepatitis; BMI; metabolic associated fatty liver disease; proton-magnetic resonance spectroscopy; alanine aminotransferase; glycosylated hemoglobin; hepatocellular carcinoma; AST-to-platelet ratio index; body mass index; Fibrosis-4 index; intrahepatic triglyceride content; aspartate aminotransferase; HbA 1c; confidence interval

Recently, a group of hepatologists proposed to rename non-alcoholic fatty liver disease (NAFLD) as metabolic associated fatty liver disease (MAFLD) with modified diagnostic criteria. We aimed to study the impact of the new definition on the epidemiology of fatty liver disease. We randomly selected 1...