Real versus imagined locomotion: A [18F]-FDG PET-fMRI comparison

• Published in: NeuroImage (Orlando, Fla.) Vol. 50; no. 4; pp. 1589 - 1598
• Main Authors: la Fougère, Christian, Zwergal, Andreas, Rominger, Axel, Förster, Stefan, Fesl, Gunther, Dieterich, Marianne, Brandt, Thomas, Strupp, Michael, Bartenstein, Peter, Jahn, Klaus
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2010; Elsevier Limited
• Subjects: Aged; Brain; Brain - blood supply; Brain - diagnostic imaging; Brain - physiology; Brain Mapping - methods; Female; Fluorodeoxyglucose F18; fMRI; Gait disorders; Glucose; Humans; Imagination - physiology; Locomotion; Locomotion - physiology; Magnetic Resonance Imaging - methods; Male; Medical imaging; Middle Aged; Neural Pathways - blood supply; Neural Pathways - diagnostic imaging; Neural Pathways - physiology; NMR; Nuclear magnetic resonance; Oxygen - blood; Patients; PET; Positron-Emission Tomography - methods; Studies; Walking; Walking - physiology; Locomotion; fMRI; PET; Gait disorders

The cortical, cerebellar and brainstem BOLD-signal changes have been identified with fMRI in humans during mental imagery of walking. In this study the whole brain activation and deactivation pattern during real locomotion was investigated by [18F]-FDG-PET and compared to BOLD-signal changes during...