A Closed-Loop Brain-Computer Interface Triggering an Active Ankle-Foot Orthosis for Inducing Cortical Neural Plasticity

• Published in: IEEE transactions on biomedical engineering Vol. 61; no. 7; pp. 2092 - 2101
• Main Authors: Xu, Ren, Jiang, Ning, Mrachacz-Kersting, Natalie, Lin, Chuang, Asin Prieto, Guillermo, Moreno, Juan C., Pons, Jose L., Dremstrup, Kim, Farina, Dario
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.07.2014; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Adult; Algorithms; Analysis of Variance; Brain; Brain-Computer Interfaces; Electroencephalography; Electroencephalography - methods; Electromyography; Electronic mail; Evoked Potentials, Motor - physiology; Female; Foot; Foot Orthoses; Human-computer interface; Humans; Male; Materials; Motor ability; Motor Cortex - physiology; Motors; Movement - physiology; Movements; Neuronal Plasticity - physiology; Orthoses; Plasticity; Rehabilitation; Robotics; Signal Processing, Computer-Assisted; Stroke Rehabilitation; Strokes; Testing; Timing; Training; Transcranial magnetic stimulation; Transcranial Magnetic Stimulation - methods; Young Adult; stroke rehabilitation; motorized ankle¿foot orthosis (MAFO); plasticity; movement-related cortical potential (MRCP); Brain¿computer interface (BCI)

In this paper, we present a brain-computer interface (BCI) driven motorized ankle-foot orthosis (BCI-MAFO), intended for stroke rehabilitation, and we demonstrate its efficacy in inducing cortical neuroplasticity in healthy subjects with a short intervention procedure (~15 min). This system detects...