Selection of influenza vaccine strains and developing pandemic vaccines

• Published in: Vaccine Vol. 20; pp. B40 - B44
• Main Author: Wood, J.M
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 20.12.2002
• Subjects: Clinical Trials as Topic; Disease Outbreaks - prevention & control; Epidemiological progression; Global Health; Humans; Influenza vaccine strains; Influenza Vaccines - genetics; Influenza Vaccines - immunology; Influenza Vaccines - supply & distribution; Influenza, Human - epidemiology; Influenza, Human - prevention & control; Influenza, Human - virology; Pandemic vaccines; Population Surveillance; Practice Guidelines as Topic; Vaccination; World Health Organization; Influenza vaccine strains; Pandemic vaccines; Epidemiological progression
• DOI: 10.1016/S0264-410X(02)00509-1
• ISSN: 0264-410X

The WHO Influenza Surveillance Programme has recently celebrated 50 years of success. The programme provides representative influenza viruses for antigenic and genetic analysis and from this information, the WHO is able to make recommendations on vaccine composition. The WHO has also a key important role to play in detecting new influenza pandemic viruses and advising on suitable vaccine strains and their use. Experience in developing vaccines for pandemics or pandemic alerts in the past, has informed us that there are considerable problems to solve, not least of which is the fact that the conventional vaccines used throughout the world are unlikely to be effective in the face of a pandemic. Different strategies need developing and testing, so that we are adequately prepared.