Are we facing a crashing wave of neuropsychiatric sequelae of COVID-19? Neuropsychiatric symptoms and potential immunologic mechanisms

• Published in: Brain, behavior, and immunity Vol. 87; pp. 34 - 39
• Main Authors: Troyer, Emily A., Kohn, Jordan N., Hong, Suzi
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.07.2020
• Subjects: Acute Disease; Anxiety - etiology; Anxiety - immunology; Anxiety - psychology; Bacterial Translocation; Betacoronavirus; Chronic Disease; Coronavirus Infections - complications; Coronavirus Infections - immunology; Coronavirus Infections - psychology; Coronavirus Infections - therapy; Coronavirus pandemic; COVID-19; Cytokine Release Syndrome - immunology; Cytokine Release Syndrome - psychology; Cytokine Release Syndrome - therapy; Demyelinating Diseases - etiology; Demyelinating Diseases - immunology; Demyelinating Diseases - physiopathology; Demyelinating Diseases - psychology; Depression - etiology; Depression - immunology; Depression - psychology; Humans; Immunologic Factors - adverse effects; Mental Disorders - etiology; Mental Disorders - immunology; Mental Disorders - psychology; Mental Health; Nervous System Diseases - etiology; Nervous System Diseases - immunology; Nervous System Diseases - physiopathology; Nervous System Diseases - psychology; Neurodegenerative Diseases - etiology; Neurodegenerative Diseases - immunology; Neurodegenerative Diseases - physiopathology; Neurodegenerative Diseases - psychology; Pandemics; Pneumonia, Viral - complications; Pneumonia, Viral - immunology; Pneumonia, Viral - psychology; Pneumonia, Viral - therapy; Post-viral neuropsychiatric sequelae; Psychoneuroimmunology; Psychotic Disorders - etiology; Psychotic Disorders - immunology; Psychotic Disorders - psychology; Public Health; Public mental health; SARS-CoV-2; Stress Disorders, Post-Traumatic - etiology; Stress Disorders, Post-Traumatic - immunology; Stress Disorders, Post-Traumatic - psychology; COVID-19; Post-viral neuropsychiatric sequelae; Public mental health; Coronavirus pandemic

•The COVID-19 pandemic is a significant source of psychological distress globally.•The novel coronavirus and host immunologic response may also directly affect brain and behavior.•Acute and delayed neuropsychiatric sequelae have been associated with past viral pandemics.•Prospective monitoring of CO...