Modeling Variation in Tumors in vivo

Transgenic mice that allow mutant cells to be visualized in situ were used to study variation in tumors. These mice carry the G11 placental alkaline phosphatase (PLAP) transgene, a mutant allele rendered incapable of producing its enzyme product by a frameshift caused by insertion of a tract of G:C...

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Published inProceedings of the National Academy of Sciences - PNAS Vol. 102; no. 7; pp. 2408 - 2413
Main Authors Stringer, James R., Larson, Jon S., Fischer, Jared M., Medvedovic, Mario, Hersh, Megan N., Boivin, Gregory P., Stringer, Saundra L., Vogt, Peter K.
Format Journal Article
LanguageEnglish
Published United States National Academy of Sciences 15.02.2005
National Acad Sciences
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